Restriction fragment pattern analysis of genomes from French isolates of suis herpes virus 1 (Aujeszky's disease virus).

Abstract:

:Purified DNA from 45 isolates of suis herpes virus 1 (SHV1) collected between 1980 and 1987 from clinical outbreaks of Aujeszky's disease on French farms was compared by restriction fragment pattern (RFP) analysis. The BamHI generated RFPs were found to be distinguishable, confirming RFP analysis as a potential epidemiological tool. The RFP could be assigned to two established major electrophoretic types and different subtypes. The RFP analysis indicated that the majority of outbreaks were caused by ADV with a central European genome type. The heterogeneity of RFPs among PRV isolates recovered from the central nervous system, lung, and foetus was not restricted specifically to one clinical entity. Variations in the virulence of the 45 isolates studied in mice, chicks, or piglets were unrelated to the RFP subtypes. One unusual RFP has been described for one strain of low virulence.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Jestin A,Blanchard P,Garbar-Chenon A,Vannier P,Nicolas JC

doi

10.1007/BF01323161

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

149-67

issue

3-4

eissn

0304-8608

issn

1432-8798

journal_volume

112

pub_type

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