B-cell epitopes of varicella-zoster virus glycoprotein II.

Abstract:

:B-cell epitopes of varicella-zoster virus glycoprotein II were mapped by means of solid phase ELISA, synthetic oligopeptides (constructed according to the Davison-Scott sequencing of the varicella-zoster virus genome) and sera from varicellae and herpes zoster patients. The individual pattern of antibody peptide binding varied considerably but at least 9 more reactive sites seemed discernible. A 31-mer-peptide corresponding to a hydrophilic segment of the glycoprotein (aa 417-447) was constructed. This peptide reacted with 2 out of 4 varicellae and 5 out of 9 zoster sera, respectively.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Kjartansdóttir A,Lycke E,Norrby SR

doi

10.1007/BF01718644

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

2465-9

issue

12

eissn

0304-8608

issn

1432-8798

journal_volume

141

pub_type

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