Isolation and phylogeny of endogenous retrovirus HERV-F family in Old World monkeys. Brief report.

Abstract:

:A new human endogenous retroviral family (HERV-F) has recently been identified from human chromosome 7q31.1-q31.3 that was identical to the XA34 cDNA clone isolated from a human glioma cDNA library with an ERV-9 env probe. We investigated pol fragments of the HERV-F family from the Old World monkeys (crab-eating monkey, African green monkey, and baboon) and analyzed these with the HERV-F (Hu-XA34). Fifteen pol fragments of the HERV-F family were detected from the Old World monkeys. They showed a high degree of sequence similarity (81-99%) with that of the HERV-F (Hu-XA34). Phylogenetic analysis of pol fragments with those of the human genome distinctively showed five groups, indicating that HERV-F family could be amplified at least five times after the original integration into the monkey genome or represent integration events independently during primate evolution.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Kim HS,Hyun BH,Takenaka O

doi

10.1007/s705-002-8327-7

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

393-400

issue

2

eissn

0304-8608

issn

1432-8798

journal_volume

147

pub_type

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