当前位置： SCI文献检索 > ARCHIVES OF VIROLOGY期刊下所有文献 > Diabetogenic potential of coxsackie B viruses in nature.

Diabetogenic potential of coxsackie B viruses in nature.

Abstract：

:Thirty-seven clinical isolates of coxsackievirus (CV) serotypes B-1, B-3, B-4, and B-5 were inoculated into male SJL mice. Twelve strains resulted in minor abnormalities of glucose metabolism in one or more of six infected mice (Tables 1 and 2). Sequential infection of male SJL mice with CVB-3, CVB-4, and CVB-5 resulted in abnormal glucose metabolism in 25 percent of the mice (Fig. 1). The glucose index of the abnormal animals was similar to that produced by sequential infection with reovirus and cytomegalovirus but less than that seen with more severe beta cell tropic agents such as streptozotocin or encephalomyocarditis virus. Infection of autoimmune New Zealand (NZB X NZW) F1 male mice with CBV-3, CVB-4, and CVB-5 resulted in transient elevation of the blood glucose concentration associated with acute acinar pancreatitis (Fig. 2). In spite of recent evidence that infection with the coxsackie B viruses can result in human diabetes mellitus, the diabetogenic potential of CVB field strains appears to be limited. Diabetes mellitus may occur as a rare event, limited to genetically susceptible hosts. Autoimmune mechanisms or repeated infection with other CVB serotypes may convert minimal beta-cell destruction into clinically overt disease.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Jordan GW,Bolton V,Schmidt NJ

doi

10.1007/BF01309826

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

213-21

issue

3-4

eissn

0304-8608

issn

1432-8798

journal_volume

86

pub_type

杂志文章

相关文献

ARCHIVES OF VIROLOGY文献大全
  • HIV-1 infection of in vitro cultured human monocytes: early events and influence of anti HIV-1 antibodies.

    abstract：:To characterize the role of the humoral immune response on HIV-1 infection of monocytes and macrophages (M phi s) we examined the susceptibility of in vitro cultured monocyte/M phi s to various HIV-1 isolates and the influence of heterologous and particularly autologous anti HIV-1 sera on this infection. Depending on ...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01538815

    authors： Arendrup M,Olofsson S,Nielsen JO,Hansen JE

    更新日期：1994-01-01 00:00:00

  • A vhs-like activity of bovine herpesvirus-1.

    abstract：:Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by ...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s007050070038

    authors： Hinkley S,Ambagala AP,Jones CJ,Srikumaran S

    更新日期：2000-01-01 00:00:00

  • Proteins specified by African swine fever virus. I. Analysis of viral structural proteins and antigenic properties.

    abstract：:At least 28 polypeptides have been identified in intracellular virus, with molecular weights ranging from 11,500 to 243,000 daltons. By treatment with Nonidet P-40 and 2-mercaptoethanol it is possible to obtain subviral particles that have lost some proteins and have a density in CsCl of 1.31 g/cm3 which is higher tha...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01314979

    authors： Tabarés E,Marcotegui MA,Fernández M,Sánchez-Botija C

    更新日期：1980-01-01 00:00:00

  • Characterization of neutralizing antibodies to bovine enterovirus elicited by synthetic peptides.

    abstract：:Six synthetic peptides corresponding to regions of bovine enterovirus (BEV), strain VG-5-27, elicited antibodies in mice which reacted with the virus in various assays. These antibodies have been characterised on the basis of their ability to (1) neutralize the virus, (2) bind to the intact virus particle in an immuno...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01309681

    authors： Smyth MS,Trudgett A,Hoey EM,Martin SJ,Brown F

    更新日期：1992-01-01 00:00:00

  • Characterization of rotavirus subgroup-specific monoclonal antibodies and use in single-sandwich ELISA systems for rapid subgrouping of human strains.

    abstract：:Two subgroup-specific monoclonal antibodies (MAb) raised in mice against group A human rotavirus were shown to react by immunoblotting with the trimeric form of VP6 of the homologous subgroup and successfully applied to development of new single-sandwich ELISA systems for rapid subgrouping of human strains. All of the...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01317927

    authors： Gerna G,Sarasini A,Torsellini M,di Matteo A,Baldanti F,Parea M,Battaglia M

    更新日期：1989-01-01 00:00:00

  • Regulation of single-strand RNA synthesis of alfalfa mosaic virus in non-transgenic cowpea protoplasts by the viral coat protein.

    abstract：:We have compared the RNA synthesis of alfalfa mosaic virus in complete (by RNAs 1, 2 and 3) and incomplete infections (by RNAs 1 and 2) of cowpea protoplasts. Both viral RNA polymerase activity and accumulation of viral RNA were measured. By annealing RNA in solution with 32P-labelled probes of plus and minus polarity...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s007050050305

    authors： Houwing CJ,van de Putte P,Jaspars EM

    更新日期：1998-01-01 00:00:00

  • Development and evaluation of a rapid recombinase polymerase amplification assay for the detection of human enterovirus 71.

    abstract：:Enterovirus 71 (EV71) is one of the most common pathogens of hand, foot, and mouth disease (HFMD). A rapid reverse transcription recombinase polymerase amplification (RT-RPA) assay was established to detect EV71 subgenotype C4 (EV71-C4). The 95% detection limit of the RT-RPA was 3.767 log10 genomic copies (LGC)/reacti...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-018-3859-x

    authors： Yin D,Zhu Y,Wang K,Wang J,Zhang X,Han M,He Y,Chen Q,Hu G

    更新日期：2018-09-01 00:00:00

  • Binding of rabbit hemorrhagic disease virus-like particles to host histo-blood group antigens is blocked by antisera from experimentally vaccinated rabbits.

    abstract：:During infection host histo-blood group antigens (HBGAs) act as attachment factors that interact with rabbit hemorrhagic disease virus (RHDV) and participate in the infectious process. In the present study, baculovirus expressing recombinant RHDV capsid protein (VP60r) as a vaccine immunogen was used to test its antig...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-017-3509-8

    authors： Song Y,Fan Z,Zuo Y,Wei H,Hu B,Chen M,Qiu R,Xue J,Wang F

    更新日期：2017-11-01 00:00:00

  • Determination of antibody concentration as the main parameter in a dengue virus antibody-dependent enhancement assay using FcγR-expressing BHK cells.

    abstract：:Dengue virus (DENV) causes a life-threatening illness, with a wide range of symptoms from mild febrile illness, dengue fever (DF), to life-threatening illness, dengue hemorrhagic fever (DHF). Antibody-dependent enhancement (ADE) is considered to be a risk factor for DHF. In the present study, we determined the paramet...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-013-1787-3

    authors： Moi ML,Takasaki T,Saijo M,Kurane I

    更新日期：2014-01-01 00:00:00

  • Poliovirus modulates Bcl-xl expression in the human U937 promonocytic cell line.

    abstract：:Poliovirus induces bcl-2-independent apoptosis in the human U937 promonocytic cell line [28]. Here we describe that this cell death, induced after viral infection, correlates with the modulation of the protooncoprotein Bcl-xl. Furthermore, poliovirus infection decreases the detected Bcl-xl in a U937 clone that overexp...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-002-0881-8

    authors： Calandria C,López-Guerrero JA

    更新日期：2002-12-01 00:00:00

  • Effect of virazole (ribavirin) on tomato spotted wilt virus in two systemic hosts, tomato and tobacco.

    abstract：:Virazole (1, beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide = Ribavirin), a synthetic nucleoside analogue, has been successfully used against tomato spotted wilt virus (TSWV) in tomato and tobacco plants. In tomato, the most efficient concentration to control TSWW was 500 mg/l while in tobacco, concentrations of 10...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01315037

    authors： De Fazio G,Caner J,Vicente M

    更新日期：1980-01-01 00:00:00

  • A two-tube multiplex real-time RT-PCR assay for the detection of four hemorrhagic fever viruses: severe fever with thrombocytopenia syndrome virus, Hantaan virus, Seoul virus, and dengue virus.

    abstract：:The aim of this study was to develop and evaluate a two-tube multiplex real-time RT-PCR assay for the detection and identification of four viral hemorrhagic fever (VHF) pathogens, severe fever with thrombocytopenia syndrome virus (SFTSV), Hantaan virus (HTNV), Seoul virus (SEOV), and dengue virus (DENV), from human cl...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-013-1677-8

    authors： Li Z,Qi X,Zhou M,Bao C,Hu J,Wu B,Wang S,Tan Z,Fu J,Shan J,Zhu Y,Tang F

    更新日期：2013-09-01 00:00:00

  • Restriction fragment pattern analysis of genomes from French isolates of suis herpes virus 1 (Aujeszky's disease virus).

    abstract：:Purified DNA from 45 isolates of suis herpes virus 1 (SHV1) collected between 1980 and 1987 from clinical outbreaks of Aujeszky's disease on French farms was compared by restriction fragment pattern (RFP) analysis. The BamHI generated RFPs were found to be distinguishable, confirming RFP analysis as a potential epidem...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01323161

    authors： Jestin A,Blanchard P,Garbar-Chenon A,Vannier P,Nicolas JC

    更新日期：1990-01-01 00:00:00

  • Recovery of mycobacteriophages from archival stocks stored for approximately 50 years in Japan.

    abstract：:Mycobacteriophage archival stocks have been kept for ca. 20-50 years in Japan. In this study, we attempted to recover mycobacteriophages from 50 archival stocks and briefly analyzed the recovered phages. The phages were recovered from 72.2% (13/18) of the lyophilized stocks that had been stored for 47-56 years. Moreov...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-018-3788-8

    authors： Ujihara T,Uchiyama J,Nasukawa T,Ando H,Murakami H,Ohara N,Ogawa M,Yamazaki T,Daibata M,Sakaguchi M,Matsuzaki S

    更新日期：2018-07-01 00:00:00

  • Differences in transmissibility and pathogenicity of reassortants between H9N2 and 2009 pandemic H1N1 influenza A viruses from humans and swine.

    abstract：:Both H9N2 subtype avian influenza and 2009 pandemic H1N1 viruses (pH1N1) can infect humans and pigs, which provides the opportunity for virus reassortment, leading to the genesis of new strains with potential pandemic risk. In this study, we generated six reassortant H9 viruses in the background of three pH1N1 strains...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-014-2009-3

    authors： He L,Wu Q,Jiang K,Duan Z,Liu J,Xu H,Cui Z,Gu M,Wang X,Liu X,Liu X

    更新日期：2014-07-01 00:00:00

  • Expression, cellular localization and antibody responses of the African swine fever virus genes B602L and K205R.

    abstract：:Previously, we identified serological immunodeterminants of African swine fever virus (ASFV), including pK205R and pB602L, without homologues in the database. pK205R is expressed as a 33-kD protein from 4 h post-infection onward, initially diffusely distributed throughout cells, and subsequently in viral factories. pK...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-008-0246-z

    authors： Gutiérrez-Castañeda B,Reis AL,Corteyn A,Parkhouse RM,Kollnberger S

    更新日期：2008-01-01 00:00:00

  • Properties of poliovirus associated protein kinase.

    abstract：:Highly purified virulent poliovirus preparations harbour an endogenous protein kinase. Enzyme activity increases significantly upon purification of infectious virus particles from infected HeLa cells. Enzyme activity is stimulated by divalent cations. The substrate specificity and the degree of stimulation of the kina...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01311330

    authors： Lackmann M,Ueckermann C,Engelmann K,Koch G

    更新日期：1987-01-01 00:00:00

  • High prevalence of hepatitis B virus pre-S mutation and its association with hepatocellular carcinoma in Qidong, China.

    abstract：:We investigated the frequency and the clinical relevance of hepatitis B virus (HBV) pre-S mutations in Qidong, China. The results showed HBV pre-S mutants were detected in 48.4% (47/97) of patients with HBV infection. Both pre-S deletion and pre-S2 start codon mutations were more frequently found in HCC than in CH pat...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-008-0176-9

    authors： Cao Z,Bai X,Guo X,Jin Y,Qian G,Tu H

    更新日期：2008-01-01 00:00:00

  • Genetic and biological characterization of Muko virus, a new distinct member of the species Great Island virus (genus Orbivirus, family Reoviridae), isolated from ixodid ticks in Japan.

    abstract：:Among the tick-borne orbiviruses (genus Orbivirus, family Reoviridae), 36 serotypes are currently classified within a single virus species, Great Island virus. In this study, we report the first characterization of a tick-borne orbivirus isolated from the tick Ixodes turdus in Japan, which we identified as a new membe...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-015-2588-7

    authors： Ejiri H,Lim CK,Isawa H,Kuwata R,Kobayashi D,Yamaguchi Y,Takayama-Ito M,Kinoshita H,Kakiuchi S,Horiya M,Kotaki A,Takasaki T,Maeda K,Hayashi T,Sasaki T,Kobayashi M,Saijo M,Sawabe K

    更新日期：2015-12-01 00:00:00

  • RT-PCR detection of the expression of the polymerase gene of a novel reptilian herpesvirus in tumor tissues of green turtles with fibropapilloma.

    abstract：:An alpha-herpesvirus has recently been associated with green turtle fibropapilloma (FP). To further understand the etiological role of this newfound green turtle herpesvirus (GTHV) in the pathogenesis of FP, expression of GTHV polymerase ( pol) gene was determined in tumors and normal-appearing nontumor tissues and or...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-002-0970-8

    authors： Lu YA,Wang Y,Aguirre AA,Zhao ZS,Liu CY,Nerurkar VR,Yanagihara R

    更新日期：2003-06-01 00:00:00

  • Contact infection of mink with 5 subtypes of avian influenza virus. Brief report.

    abstract：:Avian influenza viruses of H3N8, H11N4, H7N7, H8N4, and H5N3 infected mink by contact. ...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01309274

    authors： Okazaki K,Yanagawa R,Kida H

    更新日期：1983-01-01 00:00:00

  • Molecular characterization of CEVd strains that induce different phenotypes in Gynura aurantiaca: structure-pathogenicity relationships.

    abstract：:Two Citrus exocortis viroid isolates (CEVd-s and CEVd-129) that induce severe and mild symptoms in Gynura aurantiaca, respectively, have been characterized. They present nucleotide sequences in the pathogenicity motifs P(L), C and P(R) similar to those of "Class A" and "Class B". Infectivity and symptom expression in ...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-007-0958-5

    authors： Chaffai M,Serra P,Gandía M,Hernández C,Duran-Vila N

    更新日期：2007-01-01 00:00:00

  • Analysis of fitness differences of hepatitis B virus genotypes D and F using a cotransfection assay.

    abstract：:Hepatitis B virus (HBV) circulates as a collection of genetically related variants that evolve throughout the chronic infection. Those viral variants that have the greatest fitness are fixed. We recently showed different fitness for HBV variants involved in two epidemiological situations. To understand these fitness d...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-018-4090-5

    authors： Sevic I,Elizalde MM,González López Ledesma MM,Flichman DM,Campos RH

    更新日期：2019-02-01 00:00:00

  • Effect of DNA polymerase inhibitors on the replication of human cytomegalovirus. Brief report.

    abstract：:Aphidicolin, a specific inhibitor of cellular DNA polymerase alpha and of viral DNA polymerase, inhibits production of infectious virus and cellular and viral DNA synthesis of human cytomegalovirus (HCMV)-infected cells. On the other hand, 2',3'-dideoxynucleosides, inhibitors of DNA polymerases beta and gamma, do not ...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01310559

    authors： Gönczöl E,Plotkin SA

    更新日期：1985-01-01 00:00:00

  • Characterization and complete genomic analysis of two Salmonella phages, SenALZ1 and SenASZ3, new members of the genus Cba120virus.

    abstract：:Salmonella phages SenALZ1 and SenASZ3, two novel phages infecting Salmonella enterica, were isolated and analyzed. The genomes of these two phages consist of 154,811 and 157,630 base pairs (bp), with G+C contents of 44.56% and 44.74%, respectively. Fifty-nine of 199 open reading frames (ORFs) in the SenALZ1 genome, an...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-019-04183-3

    authors： Chen L,Guan G,Liu Q,Yuan S,Yan T,Tian L,Zhou Y,Zhao Y,Ma Y,Wei T,Fu X

    更新日期：2019-05-01 00:00:00

  • Establishment of a simplified inverse polymerase chain reaction method for diagnosis of enzootic bovine leukosis.

    abstract：:Enzootic bovine leukosis (EBL) is a malignant B-cell lymphoma of cattle caused by infection with bovine leukemia virus (BLV). It is defined by clonal and neoplastic expansion of BLV-infected B cells. Currently, multiple examinations are able to comprehensively diagnose this condition. Inverse polymerase chain reaction...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-020-04945-4

    authors： Nishimori A,Andoh K,Matsuura Y,Kumagai A,Hatama S

    更新日期：2021-01-24 00:00:00

  • Isolation of a variant of BK virus with altered restriction endonuclease pattern.

    abstract：:A papovavirus was isolated from the urine of a 24 year old female who underwent bone marrow transplantation after a relapse of acute myeloid leukemia. The virus (JL) resembles BK virus in its antigenic and growth properties, but has a different restriction endonuclease pattern after digestion with the restriction endo...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/BF01315635

    authors： Pauw W,Choufoer J

    更新日期：1978-01-01 00:00:00

  • Molecular characterization of field isolates of infectious bursal disease virus from three decades, 1987-2018, reveals a distinct genotypic subgroup in Vietnam.

    abstract：:The complete nucleotide sequence of the viral protein 2 (VP2) ORF was determined for 26 Vietnamese infectious bursal disease isolates collected from clinical outbreaks in vaccinated flocks from 1987 to 2018 and two commercial vaccine specimens. These sequences were compared for molecular classification with 42 referen...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-019-04287-w

    authors： Le XTK,Doan HTT,Do RT,Le TH

    更新日期：2019-08-01 00:00:00

  • Effect of deletion and the site of insertion in double copy anti-tat retroviral vectors: viral titres and production of anti-tat mRNA.

    abstract：:In attempts to further develop murine leukemia virus (MLV) based retroviral vectors for gene therapy, we investigated vector production and antisense expression from retroviral constructs with U3 deletions or insertions. Promoter elements in the U3 region of the 3' LTR of the vector pLXSN were deleted and replaced wit...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s007050170029

    authors： Carr JM,Calvert JK,Kumar R,Burrel CJ,Li P

    更新日期：2001-01-01 00:00:00

  • Genome sequence, prevalence and quantification of the first iflavirus identified in a phytoplasma insect vector.

    abstract：:The leafhopper Euscelidius variegatus is a natural vector of chrysanthemum yellows phytoplasma (CY) and an efficient vector of flavescence dorée phytoplasma (FD) under laboratory conditions. During a transcriptome sequencing (RNA-seq) project aimed at investigating the interactions between the insect and the two phyto...

    journal_title：Archives of virology

    pub_type： 杂志文章

    doi：10.1007/s00705-016-3158-3

    authors： Abbà S,Galetto L,Vallino M,Rossi M,Turina M,Sicard A,Marzachì C

    更新日期：2017-03-01 00:00:00