Abstract:
:Aphidicolin, a specific inhibitor of cellular DNA polymerase alpha and of viral DNA polymerase, inhibits production of infectious virus and cellular and viral DNA synthesis of human cytomegalovirus (HCMV)-infected cells. On the other hand, 2',3'-dideoxynucleosides, inhibitors of DNA polymerases beta and gamma, do not affect HCMV replication. The data show that the alpha DNA polymerases of either viral or cellular origin are required for viral DNA synthesis, and cannot be substituted by the cellular DNA polymerase beta and gamma.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Gönczöl E,Plotkin SAdoi
10.1007/BF01310559subject
Has Abstractpub_date
1985-01-01 00:00:00pages
129-34issue
1-2eissn
0304-8608issn
1432-8798journal_volume
84pub_type
杂志文章abstract::A virus associated with yellow-to-purple ringspot on honeysuckle plants has been detected and tentatively named honeysuckle ringspot virus (HnRSV). The complete nucleotide sequence of HnRSV from infected honeysuckle has been determined. The genomic RNA of HnRSV is 3,956 nucleotides in length and is predicted to contai...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1009-9
更新日期:2011-09-01 00:00:00
abstract::Norovirus has captured increasing attention as an agent of childhood diarrhoea. However, it is not known whether norovirus causes as severe diarrhoea as rotavirus, particularly among children in developing countries. In a 1-year study conducted between May 2004 and April 2005 in Recife, Brazil, norovirus was detected ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-008-0060-7
更新日期:2008-01-01 00:00:00
abstract::Molecular epidemiology can be used to identify human immunodeficiency virus (HIV) transmission clusters, usually using pol sequence for analysis. In the present study, we explored appropriate parameters to construct a simple network using HIV env and gag sequences instead of pol sequences for constructing a phylogenet...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3485-z
更新日期:2017-11-01 00:00:00
abstract::To understand the mode of persistent infection of Seoul virus in rodents, we examined the distribution of the virus genome and antibody production in infected rats. When 1-day-old rats were inoculated with the KI-83-262 strain, the S segment of viral genome was detected in sera, clots, lungs and kidneys from 3 to 184 ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718634
更新日期:1996-01-01 00:00:00
abstract::Northern pike from several locations in central Canada were observed to have two different types of hyperplastic epidermal lesions on the body and fins. One type of epidermal hyperplasia consisted of flat lesions, bluish-white in color with a granular or "gritty" appearance. Histological examination of this granular l...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310815
更新日期:1984-01-01 00:00:00
abstract::We constructed a recombinant feline herpesvirus type 1 (FHV-1) which was deleted in a defined region (450 bp) within the thymidine kinase (TK) gene (C7301dlTK) [Yokoyama et al. (1995) J Vet Med Sci 57: 709-714]. In this report, we carried out two experiments to assess the pathogenicity and vaccine efficacy of the reco...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718312
更新日期:1996-01-01 00:00:00
abstract::A potyvirus (isolate PFV-FJ) infecting passion fruit in China was identified by small-RNA sequencing. The complete genome sequence of PFV-FJ was determined to be 9974 nucleotides, excluding the poly(A) tail. PFV-FJ shares 70-72% nucleotide and 69-74% amino acid sequence identity at the polyprotein level with seven rep...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04251-8
更新日期:2019-07-01 00:00:00
abstract::Although viral protein 3 (VP3) of chicken anaemia virus (CAV) has been well recognised as an inducer of apoptosis, viral protein 2 (VP2) of the virus has only been speculated to have apoptotic activity. This has not been verified because the open reading frame (ORF) encoding VP2 completely encompasses that encoding VP...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2542-8
更新日期:2015-10-01 00:00:00
abstract::A pathogen of significance in the aquaculture sector, the Gram-negative marine bacterium Vibrio parahaemolyticus causes gastroenteritis associated with consumption of improperly prepared seafood. This bacterium can be controlled using lytic bacteriophages as an alternative to antibiotics. ϕVP-1 is a lytic phage of V. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04493-6
更新日期:2020-02-01 00:00:00
abstract::The nucleotide sequences of the SH gene of 45 new mumps virus isolates derived from different parts of Europe, Canada and USA were determined. A phylogenetic tree was constructed which confirmed the existence of three major clusters. While clustering according to geographical origin was clear in some cases each of the...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050073
更新日期:1997-01-01 00:00:00
abstract::Blue-eye disease is an emergent viral swine infection caused by porcine rubulavirus (PoRV). We have developed a qRT-PCR method to detect and quantify expression of the nucleoprotein gene for different PoRV strains. The limit of detection for this assay was 10(2) copies of synthetic RNA. Viral RNA from PoRV was detecta...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1672-0
更新日期:2013-09-01 00:00:00
abstract::Here, we report a novel virulent P2-like bacteriophage, R18C, isolated from rabbit faeces, which, in addition to Escherichia coli K-12 strains, was able to be propagated on Citrobacter rodentium strain ICC169 and a range of Shigella sonnei strains with high efficiency of plating (EOP). It represents the first lytic ba...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04424-5
更新日期:2019-12-01 00:00:00
abstract::Restriction maps of cervid herpesviruses 1 and 2 which are antigenetically related to bovine herpesvirus 1, were deduced from Southern blot hybridization with HindIII restriction fragments of BHV-1 DNA as probes. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309448
更新日期:1993-01-01 00:00:00
abstract::The genomic RNA of infectious flacherie virus (IFV), an insect picornavirus, was shown to contain a covalently attached substance which can be labeled with 125I-Bolton and Hunter reagent. This substance was found to be a protein covalently linked to the virus genome, because it cosedimented and was copurified with the...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317378
更新日期:1986-01-01 00:00:00
abstract::Cucumber green mottle mosaic virus (CGMMV) is an important pathogen of cucumber (Cucumis sativus). The molecular mechanisms mediating host-pathogen interactions are likely to be strongly influenced by microRNAs (miRNAs), which are known to regulate gene expression during the disease cycle. This study focused on 14 miR...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04152-w
更新日期:2019-04-01 00:00:00
abstract::A type III Trichomonas vaginalis virus, which may be involved in transcriptional regulation of the major surface protein gene P270 of the protozoan pathogen Trichomonas vaginalis, was purified and characterized in the present study. The complete 4844-base-pair complementary DNA sequence of the viral genome reveals ove...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0858-y
更新日期:2011-02-01 00:00:00
abstract::The oncogene E6 of human papillomavirus 8, which is associated with skin cancers in epidermodysplasia verruciformis, was transcribed and translated in vitro. The resulting 17 kDa protein did not bind to the cellular p53 in contrast to E6 of HPV16. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309654
更新日期:1992-01-01 00:00:00
abstract::Two day-old athymic (rnu/rnu) and euthymic (rnu/+) rat pups nursing immune or non-immune dams were inoculated oronasally with the Yale strain of rat virus (RV-Y). All athymic and euthymic pups (57/57) from immune dams remained clinically normal, whereas 51 of 66 athymic and euthymic pups from non-immune dams died with...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311299
更新日期:1991-01-01 00:00:00
abstract::Toscana Virus, a sandfly-associated Phlebovirus, was adapted to grow in cultured Aedes pseudoscutellaris (AP-61) mosquito cell line. No evidence of virus growth was seen after primary infection of cell monolayers under maintenance conditions. On the contrary, persistent infections were established by subculturing infe...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317004
更新日期:1985-01-01 00:00:00
abstract::Two Citrus exocortis viroid isolates (CEVd-s and CEVd-129) that induce severe and mild symptoms in Gynura aurantiaca, respectively, have been characterized. They present nucleotide sequences in the pathogenicity motifs P(L), C and P(R) similar to those of "Class A" and "Class B". Infectivity and symptom expression in ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-0958-5
更新日期:2007-01-01 00:00:00
abstract::Oncogene-containing retroviruses are generated by recombination events between viral and cellular sequences, a phenomenon called "oncogene capture". The captured cellular genes, referred to as "v-onc" genes, then acquire new oncogenic properties. We report a novel feline leukemia virus (FeLV), designated "FeLV-AKT", t...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-3192-1
更新日期:2017-04-01 00:00:00
abstract::Although surfactant-secreting type II alveolar cells have been shown to be damaged during influenzavirus pneumonia, little is known about the effects of surfactant replacement therapy. We have developed a mouse influenza model, in which viral infection can be localized to the upper respiratory tract or to both the upp...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050535
更新日期:1999-01-01 00:00:00
abstract::We have recently demonstrated the geographic isolation of rice tungro bacilliform virus (RTBV) populations in the tungro-endemic provinces of Isabela and North Cotabato, Philippines. In this study, we examined the genetic structure of the virus populations at the tungro-outbreak sites of Lanao del Norte, a province ad...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050070013
更新日期:2000-01-01 00:00:00
abstract::Different patterns of disease were observed among 11 chimpanzees who were inoculated intravenously with hepatitis E virus (HEV) positive fecal specimens from four different outbreaks (Nepal 1981, Uzbekistan 1981, Pakistan 1985, and Mexico 1986). Five chimpanzees had marginal or no liver enzyme elevations within 70 day...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050070065
更新日期:2000-01-01 00:00:00
abstract::Reassortants between a low-pathogenic avian influenza virus strain A/Duck/Primorie/2621/2001 (H5N2) and a high-yield human influenza virus strain A/Puerto Rico/8/34 (H1N1) were generated, genotyped and analyzed with respect to their yield in embryonated chicken eggs, pathogenicity for mice, and immunogenicity. A reass...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-006-0931-8
更新日期:2007-01-01 00:00:00
abstract::The 3'-terminal nucleotides of the genome segments of influenza C/Taylor/47. C/Bavaria/79 and C/Johannesburg/1/66 were identified by two RNA sequencing techniques. These comprised 11 nucleotides (3' UCGUCUUCGUC) which were found to be conserved among the genome segments of each virus. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310664
更新日期:1984-01-01 00:00:00
abstract::Virus isolate Y3V, obtained from tobacco showing leaf curl symptoms in Yunnan, China, had particles with the size and morphology typical of geminiviruses. In reactions with a set of monoclonal antibodies raised against begomoviruses, Y3V was readily differentiated from two previously studied Chinese Begomovirus isolat...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050170081
更新日期:2001-08-01 00:00:00
abstract::Gangliosides from different cells were tested for their inhibiting activity on VSV attachment to CER cells and goose erythrocytes. This inhibiting activity was enhanced when gangliosides were inserted into liposomes, in particular if containing phosphatidylserine. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310981
更新日期:1987-01-01 00:00:00
abstract::We have prepared monoclonal antibodies to each of the enteric adenoviruses types 40 and 41. Three different hybridoma cell lines were selected which produced antibody found to react by radioimmunoprecipitation with adenovirus (Ad) hexon antigens. One was specific for Ad 40, another for Ad 41, and a third one reacted w...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310718
更新日期:1987-01-01 00:00:00
abstract::Measles surveillance and epidemiological investigation are beneficial tools for genetic analysis and documentation of the interruption of transmission of endemic measles. In this study, areas of Uttar Pradesh, India, associated with measles outbreaks were investigated. Random blood and urine samples were collected fro...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1227-9
更新日期:2012-04-01 00:00:00