Clustering of mumps virus isolates by SH gene sequence only partially reflects geographical origin.

Abstract:

:The nucleotide sequences of the SH gene of 45 new mumps virus isolates derived from different parts of Europe, Canada and USA were determined. A phylogenetic tree was constructed which confirmed the existence of three major clusters. While clustering according to geographical origin was clear in some cases each of the major clusters included isolates which were widely separated in origin. The degree of variability between the sequences of SH genes of different strains and the ratio of coding to non coding differences were both very high compared to those observed in other genes such as the M and HN. A standardized system of nomenclature of mumps strains was established.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Afzal MA,Buchanan J,Heath AB,Minor PD

doi

10.1007/s007050050073

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

227-38

issue

2

eissn

0304-8608

issn

1432-8798

journal_volume

142

pub_type

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