Abstract：
:Rabbit anti-idiotypic antibodies (anti-ids) were generated against three bank vole and one human monoclonal antibody (MAb) specific for the two envelope glycoproteins of Puumala virus (G1 and G2). The anti-ids were purified by sequential immunoaffinity chromatography. Each anti-id inhibited the antigen binding of its respective MAb in a competitive ELISA. This inhibition, and the absence of cross-reactivity among the anti-ids for heterologous MAbs, showed that they all were specific for unique determinants on the antigen binding site of the homologous MAb. The anti-ids reacted with non-infected Vero E6 cells when examined by immunofluorescence and ELISA, indicating the presence of antibodies that mimic epitopes on the virus. Preincubation of Vero E6 cells with two of the anti-ids produced against neutralizing MAbs inhibited Puumala virus infection, suggesting that these two anti-ids blocked a cellular component involved in virus infection.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Lundkvist A,Scholander C,Niklasson Bdoi
10.1007/BF01309537subject
Has Abstractpub_date
1993-01-01 00:00:00pages
255-65issue
3-4eissn
0304-8608issn
1432-8798journal_volume
132pub_type
杂志文章abstract：:Segment 10, encoding nonstructural proteins 3 (NS3) and 3a (NS3a) of epizootic haemorrhagic disease virus serotype 1 (EHDV-1) was sequenced. Computer motif recognition programs were used for interpretation of the sequence data to predict a structure for NS3. Integral membrane protein theories were then applied to prod...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309968
更新日期：1995-01-01 00:00:00
abstract：:Two hundred forty million people are chronically infected with hepatitis B virus (HBV) worldwide. The rise of globalization has facilitated the emergence of novel HBV recombinants and genotypes. We evaluated HBV genotypes and recombinants, mutations associated with resistance to antivirals (AVs), progression of hepati...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3122-2
更新日期：2017-02-01 00:00:00
abstract：:Pepper chlorotic spot virus (PCSV), newly found in Taiwan, was identified as a new tospovirus based on the molecular characterization of its S RNA. In this study, the complete M and L RNA sequences of PCSV were determined. The M RNA has 4795 nucleotides (nts), encoding the NSm protein of 311 aa (34.5 kDa) in the viral...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3260-1
更新日期：2017-07-01 00:00:00
abstract：:Porcine circovirus type 2 (PCV2) is a member of the genus Circovirus in the family Circoviridae. Most subgenomic molecules of PCV2 have been mapped. Here, the first full-length sequence of a subviral molecule of PCV2 (CH-IVT12) containing a reverse complement sequence of the PCV2 genome was determined by sequencing DN...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2859-y
更新日期：2016-07-01 00:00:00
abstract：:A collection of rotavirus samples collected over a 26-year period was examined to study the dynamics of change in RV strains of genotype P[8] in a geographically defined population (Nizhny Novgorod, Russia; children under 6 years) with no vaccine pressure. Phylogenetic analysis of gene VP4 (subunit VP8*) showed the pr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1426-4
更新日期：2012-12-01 00:00:00
abstract：:The sequence variability of Barley yellow dwarf virus-PAV (PAV) and Barley yellow dwarf virus-MAV (MAV) was studied by comparing 502 nucleotides from the coat protein-encoding region of six isolates from Latvia and four from Sweden. The diversity within MAV was low (>97% sequence identity), also when compared to isola...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0242-2
更新日期：2004-04-01 00:00:00
abstract：:The four CC chemokine-like proteins (Fpv060, Fpv061, Fpv116 and Fpv121) of fowlpox virus (FWPV) were over-expressed as His-tagged versions from a T7 promoter/EMCV IRES construct in vitro, by coupled transcription/translation, or in cell culture, by co-infection with two recombinant FWPVs (one expressing the chemokine-...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0560-7
更新日期：2005-09-01 00:00:00
abstract：:Studies on rotavirus non-structural proteins have been hampered in the past by difficulties in obtaining monospecific reagents. To make such reagents available, we have expressed in the baculovirus system NSP2 and NSP3 (formerly called NS35 and NS34, respectively) of the bovine rotavirus RF and produced hybridomas aga...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309746
更新日期：1993-01-01 00:00:00
abstract：:Viral infection is usually initiated by the binding of virus particles to specific receptor molecule(s) on the host cell surface. Blocking of this step prevents the following step, penetration into the cell. In the present study, we investigated the virus-cell interactions of virions of Norwalk virus (NV), a major eti...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0143-4
更新日期：2003-09-01 00:00:00
abstract：:Bovine herpesvirus 1 (BHV-1) is a major pathogen of cattle, causing significant disease including immunosuppression in infected animals. In vitro, the surface expression of major histocompatibility complex (MHC) class I molecules, crucial for an appropriate anti-viral immune response of the host, is down-regulated by ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070038
更新日期：2000-01-01 00:00:00
abstract：:Antisera from dengue patients and dengue virus infected rabbits recognized octapeptides corresponding to linear amino acid sequences in the envelope protein of dengue 2 (Jamaica 1409). Although no peptide was recognized by sera from all dengue infected hosts, two peptides (216LPLPWLPG223 and 448FSGVSWTM455) were recog...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311358
更新日期：1989-01-01 00:00:00
abstract：:Molecular variability was assessed for 18 isolates of cowpea mild mottle virus (CPMMV, genus Carlavirus, family Betaflexiviridae) found infecting soybean in various Brazilian states (Bahia, Goiás, Maranhão, Mato Grosso, Minas Gerais, Pará) in 2001 and 2010. A variety of symptoms was expressed in soybean cv. CD206, ran...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1879-0
更新日期：2014-04-01 00:00:00
abstract：:Isolates of bovine viral diarrhea (BVD) virus were differentiated by monoclonal antibodies (MoAbs) reactive with the 56 kD viral polypeptide. Patterns of neutralizing activity of the MoAbs indicate that multiple epitopes are involved in virus neutralization. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311029
更新日期：1988-01-01 00:00:00
abstract：:Scutellaria baicalensis Georgi, a Chinese herbal decoction, has been used for the treatment of the common cold, fever and influenza virus infections. In previous studies, we found that oral administration of baicalein resulted in the inhibition of influenza A virus replication in vivo, which was linked to baicalin in ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2192-2
更新日期：2014-12-01 00:00:00
abstract：:A full-length cDNA clone of olive latent virus 1 (OLV-1), a member of the genus Necrovirus, family Tombusviridae, was subjected to site-directed mutagenesis, and coat protein gene mutants were constructed. A mutant clone, denoted Delta3297, was obtained by deleting the nucleotide in position 3297, thus inducing a fram...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0767-2
更新日期：2006-10-01 00:00:00
abstract：:We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050056
更新日期：1997-01-01 00:00:00
abstract：:An attempt has been made to devise computer software that will aid virologists to identify unknown virus isolates using the World Wide Web. Computerized information from the Animal Virus Information System was used to obtain data on various characters of a virus species. Sequence data banks are used to obtain the mole...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050394
更新日期：1998-01-01 00:00:00
abstract：:The bovine papillomavirus (BPV) transforming gene E5 is thought to modulate growth factor receptor function leading to a stimulation of growth factor signal transduction pathways. However, the influence of E5 on the range of receptor mediated changes in protein phosphorylation has not been addressed. We looked for the...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050131
更新日期：1997-01-01 00:00:00
abstract：:The genus "Tupanvirus" is a new proposed taxon to be included in the family Mimiviridae. The two known tupanvirus isolates were isolated from soda lake and oceanic sediments samples collected in Brazil and were named "tupanvirus soda lake" and "tupanvirus deep ocean", respectively. These viruses exhibit similarities t...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-4067-4
更新日期：2019-01-01 00:00:00
abstract：:Colons from ducks and chicken 1, 7, 14 and 28 days old maintained near-normal morphology up to 48 and 96 hours respectively in a system using NCTC135 medium (a part) + Dulbecco's modified Eagle's medium (9 parts ), at 37 degrees C and 95 per cent O2/5 per cent CO2. In the colon of 1 and 28 day-old ducks, duck influenz...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315007
更新日期：1981-01-01 00:00:00
abstract：:The polypeptides associated with fowlpox virus (FPV) infection of chicken embryo skin (CES) cells were examined by metabolic labelling with [35S]-methionine and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Polypeptide synthesis was followed over the first 48 hours post infection, as this was s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320959
更新日期：1987-01-01 00:00:00
abstract：:Brugmansia suaveolens mottle virus (BsMoV) was the first potyvirus isolated from "angel trumpet" (Brugmansia suaveolens), described in Brazil. In this study, the complete nucleotide (nt) genome sequence of BsMoV was determined, and the deduced amino acid (aa) sequence was analyzed. The BsMoV RNA genome consists of 987...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0798-6
更新日期：2010-10-01 00:00:00
abstract：:For selecting the neutralizing monoclonal antibodies (N-MAbs) directed to VP4 of rotavirus strain K8, which has unique VP4 neutralization epitopes, we prepared several reassortant viruses by mixed infection of two different strains K8 (serotype 1) and P (serotype 3) in vitro: three reassortant clones having VP4 of K8 ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316751
更新日期：1991-01-01 00:00:00
abstract：:In situ hybridization (ISH) and immunohistochemistry (IHC) are essential tools to characterize SARS-CoV-2 infection and tropism in naturally and experimentally infected animals and also for diagnostic purposes. Here, we describe three RNAscope®-based ISH assays targeting the ORF1ab, spike, and nucleocapsid genes and I...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04737-w
更新日期：2020-10-01 00:00:00
abstract：:An assay to characterize plasma human immunodeficiency virus 1 (HIV-1) sequences for patients with low viral loads was developed by combining the selective binding of anti-CD44 MicroBeads with a nested RT-PCR targeting the env C2V4 region. Sequences were obtained from 10 of 20 HIV+ patients who had viral loads below 4...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0659-3
更新日期：2010-06-01 00:00:00
abstract：:Measles surveillance and epidemiological investigation are beneficial tools for genetic analysis and documentation of the interruption of transmission of endemic measles. In this study, areas of Uttar Pradesh, India, associated with measles outbreaks were investigated. Random blood and urine samples were collected fro...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1227-9
更新日期：2012-04-01 00:00:00
abstract：:The nucleotide sequence of the 3' terminal region of the Australian isolate of papaya ringspot virus type W [PRSV-W (Aust)] was determined. An open reading frame (864 bp), encoding the putative coat protein gene, occurs upstream of the putative 3' untranslated region (206 bp) and poly(A) tail. A 23 amino acid sequence...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317141
更新日期：1992-01-01 00:00:00
abstract：:China experienced an outbreak of equine influenza during 2007-2008. Meanwhile, its neighbor countries, such as Mongolia, India and Japan, have also been affected by various influenza virus strains in each country. Phylogenetic analysis showed that the newly emerging Chinese strains belong to Florida sublineage clade 2...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0724-y
更新日期：2010-09-01 00:00:00
abstract：:Wheat streak mosaic virus is a serious threat in wheat-producing countries. In Germany, the virus was first recorded in 2013 near Hoym. The complete sequence of isolate Hoym was obtained and compared to all other known complete WSMV sequences, including newly collected and sequenced isolates from France and Austria. P...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2422-2
更新日期：2015-07-01 00:00:00
abstract：:Lolium latent virus (LoLV) was recently detected in the USA for the first time in ryegrass hybrids (Lolium perenne x Lolium multiflorum). The genome of one USA isolate, LoLV-US1, has now been fully sequenced. The positive strand genomic RNA is 7674 nucleotides (nt) long and is organized in five open reading frames (OR...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0108-8
更新日期：2008-01-01 00:00:00
