Abstract：
:Viral infection is usually initiated by the binding of virus particles to specific receptor molecule(s) on the host cell surface. Blocking of this step prevents the following step, penetration into the cell. In the present study, we investigated the virus-cell interactions of virions of Norwalk virus (NV), a major etiological agent for viral diarrhea. We found that histone was an extremely strong NV-binding protein. Histone H1, a heterologous histone molecule, appeared to be able to interact not only with NV particles, but also with the cell surface. Histone H1 appeared capable of effectively preventing the attachment of NV to intestinal cells, but not of other viruses. No cytotoxic effects of histone were observed under the assay conditions. These results indicate that nonsecretory histone molecules may inhibit the attachment of viruses to cells like lactoferrins. Our results suggest that by searching virus-binding molecules, we might find antiviral agents, even for new viruses.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Tamura M,Natori K,Kobayashi M,Miyamura T,Takeda Ndoi
10.1007/s00705-003-0143-4keywords:
subject
Has Abstractpub_date
2003-09-01 00:00:00pages
1659-70issue
9eissn
0304-8608issn
1432-8798journal_volume
148pub_type
杂志文章abstract：:Rabies virus (RABV) isolates from two species of canids and three species of bats were analyzed by comparing the C-terminal region of the G gene and the G-L intergenic region of the virus genome. Intercluster identities for the genetic sequences of the isolates showed both regions to be poorly conserved. Phylogenetic ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0671-7
更新日期：2010-06-01 00:00:00
abstract：:We have sequenced the genome of a novel picornavirus, rabovirus A (rat-borne virus, RaBoV-A, NC_026314), which was present in the feces of a Norway rat (Rattus norvegicus) from Berlin, Germany. This virus is related to members of the genera Enterovirus and Sapelovirus. RaboV-A contains a type II IRES that is unlike th...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2523-y
更新日期：2015-10-01 00:00:00
abstract：:Bohle iridovirus (BIV) belongs to the genus Ranavirus, of which Frog virus 3 (FV-3) is the type species. We are developing BIV as a recombinant viral delivery vector, and as a first step we located specific BIV promoter sequences to drive foreign gene expression in the recombinant virus. By comparison with FV-3 sequen...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0532-y
更新日期：2005-09-01 00:00:00
abstract：:To understand the mode of persistent infection of Seoul virus in rodents, we examined the distribution of the virus genome and antibody production in infected rats. When 1-day-old rats were inoculated with the KI-83-262 strain, the S segment of viral genome was detected in sera, clots, lungs and kidneys from 3 to 184 ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718634
更新日期：1996-01-01 00:00:00
abstract：:vp1, a gene encoding one of the capsid proteins of Taura syndrome virus, was cloned into the pGEX-6P-1 expression vector, and the resulting construct was then used to transform E. coli strain BL21. After induction, an N-terminally glutathione-S-transferase-tagged VP1 (GST-VP1) protein with a molecular mass of 80 kDa w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1460-2
更新日期：2013-01-01 00:00:00
abstract：:A small unconventional, viroid-like aetiological agent might initiate Crohn's disease (CD). Electrophoresis of radiolabelled low molecular weight nucleic acids from mesenteric lymph nodes and leucocytes did not distinguish CD-specific sequences compatible with a viroid-like agent. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310895
更新日期：1986-01-01 00:00:00
abstract：:Sera and bronchial washings from normal mice and from mice previously infected with influenza virus were analyzed for their concentration of four immunoglobulin (Ig) classes by the method of single radial immunodiffusion and for their content of specific antibody of these Ig classes by the immunofluorescent method. Ig...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314846
更新日期：1977-01-01 00:00:00
abstract：:Electron microscopy and prolonged incubation of cell cultures have revealed the presence of a papovavirus in two foetal rhesus monkey kidney cell lines, FRhK-4 and FRhK-6, which are used to grow hepatitis A virus. The papovavirus, designated FRKV, was present in culture fluids from both cell lines and in thin sections...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310654
更新日期：1984-01-01 00:00:00
abstract：:In an effort to determine whether distinct types of bovine herpesvirus 1 are responsible for causing specific syndromes, the polypeptides and DNA of 93 BHV 1 isolates from the province of Alberta as well as vaccine strains and numerous other Canadian, U.S. and European isolates were analyzed by PAGE and restriction en...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311201
更新日期：1983-01-01 00:00:00
abstract：:The genomes of all replication-competent retroviruses contain cis-acting elements that regulate gene expression. However, the identities of many of these elements remain to be characterized. Inserting sequences into the 3' untranslated region of a replication-competent spleen necrosis virus (SNV) vector disrupted its ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050486
更新日期：1999-01-01 00:00:00
abstract：:Respiratory syncytial virus (RSV) G glycoprotein mediates cell attachment through surface glycosaminoglycans (GAGs). Feldman et al. [10] suggested that specific basic amino acids in residues 184-198 of G defined a critical heparin binding domain (HBD). To further define the G HBD we made a series of truncated G protei...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0139-0
更新日期：2003-10-01 00:00:00
abstract：:Genomic DNA of blueberry red ringspot virus (genus Soymovirus, family Caulimoviridae) from highbush blueberry plants growing for years in the Czech Republic and Slovenia was sequenced. The circular dsDNA genomes consist of 8,303 and 8,299 nt, respectively, and contain eight open reading frames (ORFs) longer than 100 a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1077-x
更新日期：2011-10-01 00:00:00
abstract：:A viroid was isolated from symptomless Coleus blumei cultivar (cv.) 'Rainbow Gold' plants using the bidirectional PAGE method for analysis of small circular RNA molecules. The viriod was transmitted to viroid-free plants of Coleus blumei cv. 'Scarlet Dragonfly' by mechanical inoculation. Cloning and sequencing reveale...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718222
更新日期：1996-01-01 00:00:00
abstract：:The nature of SRV-4 infection in cynomolgus macaques remains unclear to date. Here, we report the monitoring of 24 cynomolgus monkeys that were naturally infected with SRV-4 for virus isolation, proviral load and antibody. The results indicated that the SRV-4 antibody status was statistically correlated to environment...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1068-y
更新日期：2011-11-01 00:00:00
abstract：:Five avian paramyxoviruses of serotype 8 (APMV-8) were isolated during a study monitoring wild birds in Kazakhstan in 2013 and each was further characterized. The viruses were isolated from three White-fronted geese (Anser albifrons), one Whooper swan (Cygnus cygnus), and one Little stint (Calidris minuta). Before our...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3593-9
更新日期：2018-02-01 00:00:00
abstract：:The Pasteur strain of fixed rabies virus was adapted to primary cell cultures of Japanese quail embryos and designated as MNIIVP-74. In the course of adaptation the virus pathogenicity for rabbits by the intracerebral route decreased considerably and the pathogenicity for rabbits and adult white mice by extraneural ro...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320592
更新日期：1979-01-01 00:00:00
abstract：:As a prerequisite for development of improved vaccines and diagnostic tools for control of the fish pathogen koi herpesvirus, or cyprinid herpesvirus 3 (CyHV-3), we have started to identify putative viral envelope and capsid proteins. The complete or partial CyHV-3 open reading frames ORF25, ORF65, ORF92, ORF99, ORF13...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2190-4
更新日期：2014-12-01 00:00:00
abstract：:Both H9N2 subtype avian influenza and 2009 pandemic H1N1 viruses (pH1N1) can infect humans and pigs, which provides the opportunity for virus reassortment, leading to the genesis of new strains with potential pandemic risk. In this study, we generated six reassortant H9 viruses in the background of three pH1N1 strains...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2009-3
更新日期：2014-07-01 00:00:00
abstract：:Allexiviruses are economically important garlic viruses that are involved in garlic mosaic diseases. In this study, we characterized the allexivirus cysteine-rich protein (CRP) gene located just downstream of the coat protein (CP) gene in the viral genome. We determined the nucleotide sequences of the CP and CRP genes...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3749-2
更新日期：2018-06-01 00:00:00
abstract：:Arginine is necessary for the development of the cytopathogenic effect of human cytomegalovirus in human embryonic fibroblasts. It is also required, though in greater concentrations, for the production of infective virions, the requirement being at an early stage of replication. Inhibitor studies suggested that this b...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01318146
更新日期：1975-01-01 00:00:00
abstract：:The interaction between the nucleocapsid (N) protein of mouse hepatitis virus (MHV) and RNA was studied in an effort to define portions of the N molecule that participate in binding to RNA. N mRNAs transcribed from SP6 and T7 vectors were translated in a rabbit reticulocyte lysate. Analysis of synthesized N protein in...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309634
更新日期：1992-01-01 00:00:00
abstract：:The yeast two-hybrid system has been used to identify domains of the Newcastle disease virus (NDV) phosphoprotein (P) involved in self-association and interaction with the nucleocapsid protein (NP). Deletion analysis was used to map the domain(s) of the P protein involved in P:P and P:NP interactions. The C-terminal 4...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0439-z
更新日期：2005-03-01 00:00:00
abstract：:Spartina mottle virus (SpMV), an unassigned member of the family Potyviridae, has been known since 1980, when it was first described in England and Wales in symptomatic plants of the genus Spartina. In infected cells, flexuous particles and pinwheel inclusion bodies were found that resemble those of potyvirids. To dat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04726-z
更新日期：2020-10-01 00:00:00
abstract：:An assay to characterize plasma human immunodeficiency virus 1 (HIV-1) sequences for patients with low viral loads was developed by combining the selective binding of anti-CD44 MicroBeads with a nested RT-PCR targeting the env C2V4 region. Sequences were obtained from 10 of 20 HIV+ patients who had viral loads below 4...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0659-3
更新日期：2010-06-01 00:00:00
abstract：:Reassortants between a low-pathogenic avian influenza virus strain A/Duck/Primorie/2621/2001 (H5N2) and a high-yield human influenza virus strain A/Puerto Rico/8/34 (H1N1) were generated, genotyped and analyzed with respect to their yield in embryonated chicken eggs, pathogenicity for mice, and immunogenicity. A reass...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0931-8
更新日期：2007-01-01 00:00:00
abstract：:The genomes of a large number of highly diverse novel circular DNA viruses from a wide range of sources have been characterised in recent years, including circular single-stranded DNA (ssDNA) viruses that share similarities with plant-infecting ssDNA viruses of the family Geminiviridae. Here, we describe six novel cir...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2358-6
更新日期：2015-05-01 00:00:00
abstract：:Mouse embryo fibroblasts and mouse adrenal tumor cells support the replication of encephalomyocarditis (EMC) virus, whereas rat glial and rat hepatoma cells are non-permissive. These differences in susceptibility were not due to the lack of virus attachment to rat cells. The findings that rat cells could be transfecte...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310884
更新日期：1986-01-01 00:00:00
abstract：:Styrian oil pumpkin seedlings (Cucurbita pepo L. subsp. pepo var. styriaca GREB: .) were treated for 48 h with 1 mM OTC (L-2-oxothiazolidine-4-carboxylic acid) in order to artificially increase cellular glutathione content. They were inoculated with zucchini yellow mosaic virus (ZYMV) 10 days later. The effects of OTC...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0880-2
更新日期：2007-01-01 00:00:00
abstract：:Dengue virus is the most important arbovirus that affects humans, and it can establish persistent infections, especially in insect-derived cell cultures. Defective viral genomes have been implicated in the establishment and maintenance of persistent infections with several flaviviruses; however, there exists almost no...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1525-2
更新日期：2013-03-01 00:00:00
abstract：:Out of 136 new phages, 80 (59%) are classified into 23 species according to morphology and physicochemical properties. Six new species are described and species beta 4, from a previous classification scheme, is renamed T1. The morphology of 36 phage species is schematically represented. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
