Encephalomyocarditis virus can bind to and transfect non-permissive cells.

Abstract:

:Mouse embryo fibroblasts and mouse adrenal tumor cells support the replication of encephalomyocarditis (EMC) virus, whereas rat glial and rat hepatoma cells are non-permissive. These differences in susceptibility were not due to the lack of virus attachment to rat cells. The findings that rat cells could be transfected with RNA derived from EMC virus indicates that the block in viral replication in these cells occurs at some point between attachment and uncoating of virus, probably at the level of uncoating.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Donta ST,Shanley JD,Damiano-Burbach P

doi

10.1007/BF01310884

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

301-7

issue

3-4

eissn

0304-8608

issn

1432-8798

journal_volume

88

pub_type

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