Abstract:
:Sera and bronchial washings from normal mice and from mice previously infected with influenza virus were analyzed for their concentration of four immunoglobulin (Ig) classes by the method of single radial immunodiffusion and for their content of specific antibody of these Ig classes by the immunofluorescent method. IgA were not detected in bronchial washings from normal mice. The IgA/IgG ratio was not higher than 0.33 in infected mice. The IgA level increased briefly in infected bronchial washings, but the levels of IgG2 and particularly of IgG1 exhibited a longer and higher increase. The maximal increase of these three Ig classes occurred by the seventh day and might have derived from transsudated serum. IgM was not identified in normal bronchial washings, but immunofluorescence detected IgM in infected washings, which also showed specific antibody in each of the four Ig classes. IgG2 and IgM contained antibody in greatest, IgA in lower concentration. Our results indicate that the most part of bronchial antibody was produced locally, since the ratio of Ig concentration to antibody titre of each Ig class was consistently higher for bronchial washings than for sera. An anamnestic secretory antibody response could not be demonstrated in bronchial washings.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Lemercier G,Neveu D,Morel J,Fontanges Rdoi
10.1007/BF01314846subject
Has Abstractpub_date
1977-01-01 00:00:00pages
45-53issue
1-2eissn
0304-8608issn
1432-8798journal_volume
53pub_type
杂志文章abstract::Here we describe the results of experimental infections of captive big brown bats (Eptesicus fuscus) with three newly isolated bat lyssaviruses from Eurasia (Aravan, Khujand, and Irkut viruses). Infection of E. fuscus was moderate (total, 55-75%). There was no evidence of transmission to in-contact cage mates. Incubat...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-005-0785-0
更新日期:2006-10-01 00:00:00
abstract::In this study, we obtained the whole genomes of three porcine bocaparvovirus (PBoV) strains (GD6, GD10, and GD23) by polymerase chain reaction. Sequence analysis showed that all three field strains belonged to PBoV group 3 (G3). The phylogenetic trees based on NS1, NP1, and VP1 differed to the extent that these PBoVs ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3606-8
更新日期:2018-03-01 00:00:00
abstract::To test the role of neutralizing antibodies (nAbs) and receptor adaptation in interspecies transmission of influenza virus, two H5N1 strains, isolated from human and avian hosts, with four amino acid differences in hemagglutinin (HA) and seven HA mutations were studied. We found that a mutation at amino acid position ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1056-2
更新日期:2011-10-01 00:00:00
abstract::A full length cDNA copy of the genomic RNA of lettuce mosaic virus (LMV) was constructed under the control of an enhanced CaMV 35S promoter and of the NOS terminator. This construct was found infectious when inoculated to lettuce plants. The intron II of the bean nitrite reductase gene was engineered into the LMV FL c...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050474
更新日期:1998-01-01 00:00:00
abstract::An electron microsopic study of cell cultures and bovine foetal tracheal organ cultures infected with infectious bovine rhinotracheitis (IBR) virus showed the following. a) The difference in the site at which the outer envelope is acquired in the infected cell is responsible for some morphological differences between ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317842
更新日期:1976-01-01 00:00:00
abstract::Exposure of human lung fibroblasts to human cytomegalovirus (HCMV) stimulated a rapid increase in the release of [3H] from cells prelabelled with radiolabelled arachidonic acid ([3H]AA). Maximum stimulation of [3H] release was observed at 20 min postinfection and was quantitatively similar to that induced by the tumor...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316678
更新日期:1990-01-01 00:00:00
abstract::Hepatitis C virus (HCV) infection causes acute and chronic liver disease and may lead to cirrhosis, liver failure or hepatocellular carcinoma. The behavior of illicit drug users (DUs) typically exposes them to risks of viral infection. In the Brazilian Amazon region, a number of studies have identified high rates of d...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3656-y
更新日期:2018-03-01 00:00:00
abstract::Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by the SFTS virus (SFTSV). Hubei Province is a major epidemic area for SFTS in China. In this study, quantitative reverse-transcription polymerase chain reaction (qRT-PCR) and serological testing (IgM) were used simultaneously ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-018-3993-5
更新日期:2018-12-01 00:00:00
abstract::Nanoviruses are multi-component plant-infecting single-stranded DNA viruses. Using a viral metagenomics-informed approach, a new nanovirus and two associated alphasatellite molecules have been identified in an uncultivated asymptomatic Vicia cracca plant in the Rhône region of France. This novel nanovirus genome inclu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3634-4
更新日期:2018-03-01 00:00:00
abstract::Begomovirus infection is becoming a threat in fresh-market tomato in Argentina, where mixed infections with begomoviruses are common. The complete sequence of a begomovirus isolate infecting tomato sampled in Salta was molecularly characterized. Phylogenetic analysis showed that this virus isolate is closely related t...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1355-2
更新日期:2012-10-01 00:00:00
abstract::Hybridomas secreting monoclonal antibodies against herpes simplex virus (HSV) DNA binding proteins (DBP) have been produced. Five HSV DBP have been characterized according to molecular weight, affinity for DNA, kinetic class and localization within the infected cell. By preparing an immunoadsorbent column from antibod...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314300
更新日期:1984-01-01 00:00:00
abstract::Anti-human T-lymphotropic virus type I/II (HTLV-I/II) antibodies were screened by particle agglutination test in a total of 66 patients with thalassemia major who received multiple transfusion from paid donors at the Blood Transfusion Hematology Center of Ho Chi Minh City in South Vietnam. HTLV-II infection was confir...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050170
更新日期:1997-07-01 00:00:00
abstract::Utilizing co-transfection of DNA from glycoprotein gB- strain of HSV1 and cloned fragments of several simian alpha-herpesviruses containing the UL26, UL27 (gB glycoprotein), and UL28 gene homologs, replication-competent recombinant viruses were produced. Genetic analysis of one HSV1/SA8 recombinant (HSV1/SgB) demonstr...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050114
更新日期:1997-01-01 00:00:00
abstract::Mengovirus, extracted from infected L-cell cultures with Freon 113 and concentrated from the aqueous phase with polyethyleneglycol, was chromatographed on protein-coated controlled pore glass (CPG). The covalent binding of protein to CPG is described. Further purification and concentration of mengovirus was achieved b...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315283
更新日期:1978-01-01 00:00:00
abstract::A replication-defective, recombinant Sindbis virus vector was utilized in a novel immunization strategy to induce humoral and cellular responses against hepatitis C virus (HCV). The recombinant vector, pVaXJ-E1E2, expressing the gene for HCV glycoproteins E2 and E1, was constructed by inserting the E1E2 gene into the ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1564-8
更新日期:2013-05-01 00:00:00
abstract::The complement fixing antigens of rubella virus have been found to contain virion envelope but little nucleocapsid polypeptides. They are also shown to be associated with two additional polypeptides of host origin. Evidence is presented to suggest that the complement fixing antigens are structural components of the pl...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315301
更新日期:1986-01-01 00:00:00
abstract::Human cytomegalovirus (HCMV) has evolved several immune-evasion strategies. One strategy involves encoding Fcgamma receptor (FcγR)-like proteins that thwart the Fcγ-mediated effector functions. Our aim was to determine whether GM allotypes-immunoglobulin γ chain determinants expressed primarily on the Fc segment-modul...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-0937-8
更新日期:2011-05-01 00:00:00
abstract::As a prerequisite for development of improved vaccines and diagnostic tools for control of the fish pathogen koi herpesvirus, or cyprinid herpesvirus 3 (CyHV-3), we have started to identify putative viral envelope and capsid proteins. The complete or partial CyHV-3 open reading frames ORF25, ORF65, ORF92, ORF99, ORF13...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2190-4
更新日期:2014-12-01 00:00:00
abstract::Measles virus and mumps virus (MeV and MuV) are enveloped RNA viruses used for production of live attenuated vaccines for prophylaxis of measles and mumps disease, respectively. For biotechnological production of and basic research on these viruses, the preparation of highly purified and infectious viruses is a prereq...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-2801-3
更新日期:2016-06-01 00:00:00
abstract::To characterize the role of the humoral immune response on HIV-1 infection of monocytes and macrophages (M phi s) we examined the susceptibility of in vitro cultured monocyte/M phi s to various HIV-1 isolates and the influence of heterologous and particularly autologous anti HIV-1 sera on this infection. Depending on ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01538815
更新日期:1994-01-01 00:00:00
abstract::In the current study, the complete genome sequence of a member of the family Astroviridae isolated from pigeons was determined through genetic characterization and phylogeny analysis. The isolated genome sequence was proposed to be that of pigeon avian nephritis virus (ANV), whose genome structure and characteristics ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1034-8
更新日期:2011-09-01 00:00:00
abstract::The gene encoding the capsid protein of a genogroup I Norwalk-like virus (NLV) (Hu/NLV/Stav/95/Nor) was cloned and expressed in insect cells using a baculovirus vector. The His-tagged recombinant capsid protein (rStav) was antigenic and immunogenic, showed an apparent molecular weight of approximately 68 kD in protein...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050665
更新日期:2000-01-01 00:00:00
abstract::In attempts to further develop murine leukemia virus (MLV) based retroviral vectors for gene therapy, we investigated vector production and antisense expression from retroviral constructs with U3 deletions or insertions. Promoter elements in the U3 region of the 3' LTR of the vector pLXSN were deleted and replaced wit...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050170029
更新日期:2001-01-01 00:00:00
abstract::Hippeastrum chlorotic ringspot virus (HCRV) is a novel tospovirus that was identified in Yunnan Province, China, in 2013. We have sequenced the HCRV L gene, which is 8909 nt long and encodes the RNA-dependent RNA polymerase (2873 amino acids, 330.8 kDa). The HCRV L protein shared highest similarity (89.4 %) with that ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2100-9
更新日期:2014-10-01 00:00:00
abstract::The aim of this study was to develop and evaluate a two-tube multiplex real-time RT-PCR assay for the detection and identification of four viral hemorrhagic fever (VHF) pathogens, severe fever with thrombocytopenia syndrome virus (SFTSV), Hantaan virus (HTNV), Seoul virus (SEOV), and dengue virus (DENV), from human cl...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1677-8
更新日期:2013-09-01 00:00:00
abstract::Current subgenotype 2.1 isolates of classical swine fever virus (CSFV) play a dominant role in CSF outbreaks in China, and a novel sub-subgenotype 2.1g of CSFV was recently identified, but the complete genome sequence of this new sub-subgenotype has not been reported. In this study, complete genome of 2.1g isolate GD1...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-2932-6
更新日期:2016-09-01 00:00:00
abstract::Bovine lactoferrin (LF) and ribavirin (Rbv) were tested as antiviral agents against Seoul type hantavirus (SR-11 strain) in vitro. Hantaviral foci number in Vero E6 cells infected with SR-11 was reduced with LF treatment by 5 days post infection to obtain a 50% effective dose (ED50) of 2500 microg/ml, while pretreatme...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050070077
更新日期:2000-01-01 00:00:00
abstract::The influence of hepatitis B virus (HBV) gene heterogeneity on the failure of HBV vaccination in eastern China remains unknown. Here, we assigned 78 hepatitis B surface antigen (HBsAg)-carrier mothers to two groups: 41 mothers from whom transmission of HBV to their children was successfully prevented and 37 mothers wh...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0315-y
更新日期:2009-01-01 00:00:00
abstract::Begomoviruses have been detected infecting the weed Cnidoscolus urens (family Euphorbiaceae) since 2004, but the viral species to which these viruses belonged was not known. Here, we report for the first time the complete genome sequence of a bipartite begomovirus obtained from C. urens collected in the state of Alago...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-2919-3
更新日期:2016-09-01 00:00:00
abstract::A virus associated with yellow-to-purple ringspot on honeysuckle plants has been detected and tentatively named honeysuckle ringspot virus (HnRSV). The complete nucleotide sequence of HnRSV from infected honeysuckle has been determined. The genomic RNA of HnRSV is 3,956 nucleotides in length and is predicted to contai...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1009-9
更新日期:2011-09-01 00:00:00