Human T-lymphotropic Virus Type II Infection inVietnamese Thalassemic Patients.

Abstract:

:Anti-human T-lymphotropic virus type I/II (HTLV-I/II) antibodies were screened by particle agglutination test in a total of 66 patients with thalassemia major who received multiple transfusion from paid donors at the Blood Transfusion Hematology Center of Ho Chi Minh City in South Vietnam. HTLV-II infection was confirmed in 6 patients (9.1%) by Western blot analysis and/or polymerase chain reaction. Phylogenetic analysis revealed that long terminal repeat sequences of HTLV-II proviruses from 5 thalassemic patients in Vietnam belonged to the same phylogenetic subgroup of HTLV-IIb as those from intravenous drug abusers in North America and Europe. These data shed light on the route of introducing HTLV-II into Vietnam.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Lin MT,Nguyen BT,Binh TV,Be TV,Chiang TY,Tseng LH,Yang YC,Lin KH,Chen Y-

doi

10.1007/s007050050170

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

1429-1440

issue

7

eissn

0304-8608

issn

1432-8798

pii

10.1007/s007050050170

journal_volume

142

pub_type

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