Abstract:
:Hybridomas secreting monoclonal antibodies against herpes simplex virus (HSV) DNA binding proteins (DBP) have been produced. Five HSV DBP have been characterized according to molecular weight, affinity for DNA, kinetic class and localization within the infected cell. By preparing an immunoadsorbent column from antibody TI8, its specific DBP was purified to apparent homogeneity. The purified DBP retained the ability to bind to DNA.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
la Thangue NB,Chan WLdoi
10.1007/BF01314300subject
Has Abstractpub_date
1984-01-01 00:00:00pages
13-33issue
1-2eissn
0304-8608issn
1432-8798journal_volume
79pub_type
杂志文章abstract::The complete genomes of a monopartite begomovirus (genus Begomovirus, family Geminiviridae) and an associated betasatellite found infecting Vernonia amygdalina Delile (family Compositae) in Uganda were cloned and sequenced. Begomoviruses isolated from two samples showed the highest nucleotide sequence identity (73.1% ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-3175-2
更新日期:2017-04-01 00:00:00
abstract::Norovirus (NoV) infection is the most common cause of nonbacterial acute gastroenteritis, which affects both adults and children. However, the molecular epidemiology of NoV in adults with acute gastroenteritis in China has not been investigated extensively. In this study, we investigated the occurrence of NoV infectio...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2440-0
更新日期:2015-07-01 00:00:00
abstract::We investigated the cis-acting sequences of the promoter regulating the gene encoding the glycoprotein C (gC) of bovine herpesvirus 1 (BoHV-1), a gene of the gamma1 class. S1 nuclease protection assays revealed that gC transcription initiated predominantly at position C18281 of the viral genome, corresponding to 21 an...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-002-0898-z
更新日期:2003-01-01 00:00:00
abstract::The highly conserved encapsidation signal (epsilon) of hepatitis B viral (HBV) pregenomic RNA has been reported as an essential component for encapsidation and protein priming of HBV polymerase. Here, we report that two HBV epsilon RNA-binding host proteins (80 and 43 kDa) and a copurifying protein (100 kDa) were puri...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050200001
更新日期:2002-03-01 00:00:00
abstract::Human metapneumovirus (hMPV) is an important respiratory pathogen in young children whose seasonal activity varies substantially from year to year among different populations. This study was conducted to investigate if there was a seasonal variation in the incidence of hMPV infection in young children and possible ass...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1492-7
更新日期:2013-02-01 00:00:00
abstract::Leakage of glutamic-oxalacetic transaminase was monitored as an indicator of cell damage during a 48-hour period in which maximum virus replication occurred. There was increased leakage of the enzyme from HEp-2 cells infected with highly oncogenic adenovirus type 12. Leakage from cells infected with adenovirus types 1...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315705
更新日期:1983-01-01 00:00:00
abstract::China experienced an outbreak of equine influenza during 2007-2008. Meanwhile, its neighbor countries, such as Mongolia, India and Japan, have also been affected by various influenza virus strains in each country. Phylogenetic analysis showed that the newly emerging Chinese strains belong to Florida sublineage clade 2...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0724-y
更新日期:2010-09-01 00:00:00
abstract::TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-like mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% preva...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s705-002-8310-6
更新日期:2002-01-01 00:00:00
abstract::Using gag protein of feline immunodeficiency virus (FIV) expressed in Escherichia coli, an enzyme-linked immunosorbent assay (ELISA) system was developed for detection of antibodies to FIV gag protein in cat sera. With serum samples from cats experimentally infected with several strains and an infectious molecular clo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309815
更新日期:1992-01-01 00:00:00
abstract::In this study, a porcine rotavirus was isolated from a fecal sample from a diarrheic piglet in Jiangsu Province, China. Rotavirus-specific cytopathic effects were observed after 12 blind passages on MA-104 cells, yielding a virus titer of 10(6.125) TCID50/ml. By applying an 80 % nucleotide cutoff value and the RotaC(2...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2347-9
更新日期:2015-05-01 00:00:00
abstract::Bohle iridovirus (BIV) belongs to the genus Ranavirus, of which Frog virus 3 (FV-3) is the type species. We are developing BIV as a recombinant viral delivery vector, and as a first step we located specific BIV promoter sequences to drive foreign gene expression in the recombinant virus. By comparison with FV-3 sequen...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-005-0532-y
更新日期:2005-09-01 00:00:00
abstract::Type I interferon (IFN) exerts strong antiviral activity, particularly against human immunodeficiency virus (HIV), and although several viral proteins have been shown to deregulate IFN induction, little is known about the induction of type I IFNs by HIV RNAs. In the present study, we used the stable isotope labeling w...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2372-8
更新日期:2015-05-01 00:00:00
abstract::Genomic DNA of blueberry red ringspot virus (genus Soymovirus, family Caulimoviridae) from highbush blueberry plants growing for years in the Czech Republic and Slovenia was sequenced. The circular dsDNA genomes consist of 8,303 and 8,299 nt, respectively, and contain eight open reading frames (ORFs) longer than 100 a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1077-x
更新日期:2011-10-01 00:00:00
abstract::Codiaeum variegatum (common name, garden croton) is an ornamental plant grown for its bright yellow variegated leaf morphology. Two C. variegatum plants with upward leaf curling and vein swelling symptoms were collected in Faisalabad, Pakistan. Sequencing of clones obtained by PCR amplification with specific primers s...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04633-3
更新日期:2020-08-01 00:00:00
abstract::A filamentous virus, with particles 600-650 nm long, was purified from Narcissus pseudonarcissus (daffodil) in Hangzhou and an antiserum prepared. After mechanical inoculation, the virus could be detected serologically in Narcissus species but not in some commonly used virus indicators. Infection was symptomless. The ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-006-0801-4
更新日期:2006-11-01 00:00:00
abstract::MicroRNAs (miRNAs) are a new class of well-conserved small noncoding RNAs that mediate posttranscriptional gene regulation. Hepatitis B virus (HBV) causes various liver diseases, including chronic hepatitis, liver cirrhosis and hepatocellular cancer. Recent data have indicated HBV alters miRNAs expression patterns, bu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2286-x
更新日期:2015-03-01 00:00:00
abstract::Hepatitis B virus (HBV) infection has a major effect on health care systems, with about one-third of the world's population currently infected with the virus. There is an effective vaccine against HBV, which contains a recombinant "surface antigen" produced in an expression vector. Vaccination has proved to be success...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-008-0206-7
更新日期:2008-01-01 00:00:00
abstract::The distribution of African swine fever virus (ASFV) in whole blood, plasma, red blood cells (RBC) and white blood cell (WbC) sub-populations was determined in pigs infected with virulent virus. Changes in the RBC and WBC populations were also examined. Total WBC counts decreased and RBC numbers remained unchanged dur...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315054
更新日期:1977-01-01 00:00:00
abstract::The nucleotide sequences of the 3' leader and 5' trailer regions were determined for genomic RNA of bovine respiratory syncytial virus (BRSV) strain A-51908. The leader and trailer sequences are '45' and '161' nucleotides in length, respectively. The functionality of BRSV leader and trailer sequences and their recogni...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050719
更新日期:1999-01-01 00:00:00
abstract::Mengovirus, extracted from infected L-cell cultures with Freon 113 and concentrated from the aqueous phase with polyethyleneglycol, was chromatographed on protein-coated controlled pore glass (CPG). The covalent binding of protein to CPG is described. Further purification and concentration of mengovirus was achieved b...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315283
更新日期:1978-01-01 00:00:00
abstract::The PI3K/Akt signalling pathway is a crucial signalling cascade that regulates transcription, protein translation, cell growth, proliferation, cell survival, and metabolism. During viral infection, viruses exploit a variety of cellular pathways, including the well-known PI3K/Akt signalling pathway. Conversely, cells r...
journal_title:Archives of virology
pub_type: 杂志文章,评审
doi:10.1007/s00705-020-04740-1
更新日期:2020-10-01 00:00:00
abstract::This report describes the first isolation and partial characterization of a herpesvirus from the harbor seal (Phoca vitulina). The virus was isolated during a disease outbreak in a group of young seals nursed in a seal orphanage in The Netherlands. Almost half of the seals died with symptoms of acute pneumonia and foc...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309828
更新日期:1985-01-01 00:00:00
abstract::To characterize the role of the humoral immune response on HIV-1 infection of monocytes and macrophages (M phi s) we examined the susceptibility of in vitro cultured monocyte/M phi s to various HIV-1 isolates and the influence of heterologous and particularly autologous anti HIV-1 sera on this infection. Depending on ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01538815
更新日期:1994-01-01 00:00:00
abstract::The numbers of the carbohydrate side chains have been analyzed on a series of subtype 7 hemagglutinins of influenza A virus. The procedure employed involves growth of the virus in the presence of the trimming inhibitor N-methyl-1-desoxynojirimycin followed by controlled removal of the resulting mannose-rich oligosacch...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314433
更新日期:1987-01-01 00:00:00
abstract::Isolates of bovine viral diarrhea (BVD) virus were differentiated by monoclonal antibodies (MoAbs) reactive with the 56 kD viral polypeptide. Patterns of neutralizing activity of the MoAbs indicate that multiple epitopes are involved in virus neutralization. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311029
更新日期:1988-01-01 00:00:00
abstract::Canine enteric coronaviruses (CCoVs) are important enteric pathogens of dogs. CCoVs with different variations are typically pantropic and pathogenic in dogs. In this study, we isolated a CCoV, designated HLJ-073, from a dead 6-week-old male Pekingese with gross lesions and diarrhea. Interestingly, sequence analysis su...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04296-9
更新日期:2019-08-01 00:00:00
abstract::We determined the complete genome sequence of a South Korean (SK) isolate of Brugmansia mosaic virus (BruMV), which has recently been proposed to be a member of a new species in the genus Potyvirus. The genomic RNA of BruMV isolate SK is 9781 nucleotides in length (excluding the 3'-terminal poly (A)) and shares comple...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1693-8
更新日期:2013-09-01 00:00:00
abstract::The complete genome of a novel mycovirus, Puccinia striiformis mitovirus 1 (PsMV1), derived from the wheat stripe rust fungus Puccinia striiformis strain SCSN-10, was sequenced and analyzed. The full-length cDNA sequence is 2496 bp in length with a predicted AU content of 57.65% in the genomic RNA. Sequence analysis i...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-018-04134-4
更新日期:2019-03-01 00:00:00
abstract::Chimeric plant viruses are emerging as promising vectors for use in innovative vaccination strategies. In this context, cucumber mosaic virus (CMV) has proven to be a suitable carrier of the hepatitis C virus (HCV)-derived R9 mimotope. In the present work, a new chimeric CMV, expressing on its surface the HCV-derived ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-006-0916-7
更新日期:2007-01-01 00:00:00
abstract::In 1991 and 1992, H1N2 influenza A viruses were isolated from the lungs of pigs with overt signs of respiratory disease at farms in the Chiba and Kanagawa prefectures of Japan. To determine the genetic origin of these isolates, we phylogenetically analyzed partial nucleotide sequences of their genes. The results indic...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050415
更新日期:1998-01-01 00:00:00