Abstract:
:In 1991 and 1992, H1N2 influenza A viruses were isolated from the lungs of pigs with overt signs of respiratory disease at farms in the Chiba and Kanagawa prefectures of Japan. To determine the genetic origin of these isolates, we phylogenetically analyzed partial nucleotide sequences of their genes. The results indicate that influenza viruses possessing the N2 of human influenza virus and seven other gene segments of classical H1N1 swine influenza virus, which were first isolated in 1980, have become established in Japanese pigs.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Ito T,Kawaoka Y,Vines A,Ishikawa H,Asai T,Kida Hdoi
10.1007/s007050050415subject
Has Abstractpub_date
1998-01-01 00:00:00pages
1773-82issue
9eissn
0304-8608issn
1432-8798journal_volume
143pub_type
杂志文章abstract::In vivo transfection by intramuscular injection with plasmids expressing the immunogenic proteins of microbial pathogens has considerable potential as a vaccination strategy against many pathogens of both man and animals. Here we report that weanling mice given a single intramuscular injection of 50 micrograms of a pl...
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