Leakage of cellular enzyme during replication of oncogenic and nononcogenic adenoviruses.

Abstract:

:Leakage of glutamic-oxalacetic transaminase was monitored as an indicator of cell damage during a 48-hour period in which maximum virus replication occurred. There was increased leakage of the enzyme from HEp-2 cells infected with highly oncogenic adenovirus type 12. Leakage from cells infected with adenovirus types 18 and 31 (highly oncogenic), types 3,7 and 14 (weakly oncogenic), and types 1, 2 and 5 (nononcogenic) was similar to that from uninfected HEp-2 cells, even after the appearance of advanced virus-induced cytopathology.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Bardell D

doi

10.1007/BF01315705

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

69-72

issue

1

eissn

0304-8608

issn

1432-8798

journal_volume

76

pub_type

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