Abstract：
:China experienced an outbreak of equine influenza during 2007-2008. Meanwhile, its neighbor countries, such as Mongolia, India and Japan, have also been affected by various influenza virus strains in each country. Phylogenetic analysis showed that the newly emerging Chinese strains belong to Florida sublineage clade 2, as well as the Indian strain Jammu-Katra/6/08 and the Mongolian strain Mongolia/1/08. All of these strains were derived from European strains of this clade, such as the Newmarket/1/07 and Cheshire/1/07 strains, but these were not related to Japanese strains isolated around the same time (Florida sublineage clade 1) or to Chinese strains isolated in the 1990s (European lineage). Some unique amino acid changes were found in the antigenic sites in Asian strains of Florida sublineage clade 2. Moreover, the loss of a glycosylation site was found in the Liaoning/9/08 strain. From these studies, we have determined that equine influenza viruses in China have evolved with some new characteristics during recent years, and this emphasizes the importance of continued equine influenza virus surveillance in China.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Qi T,Guo W,Huang WQ,Li HM,Zhao LP,Dai LL,He N,Hao XF,Xiang WHdoi
10.1007/s00705-010-0724-ysubject
Has Abstractpub_date
2010-09-01 00:00:00pages
1425-32issue
9eissn
0304-8608issn
1432-8798journal_volume
155pub_type
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