Electron microscopic study of human immunodeficiency virus type 1 (HIV-1) core structure: two RNA strands in the core of mature and budding particles.

Abstract:

:The basic structure of human immunodeficiency virus type 1 (HIV-1) has been investigated morphologically; however, the internal structure of HIV-1 core is not well understood. We studied the internal structures by transmission electron microscopy. We modified the method for electron staining of ultrathin sections and processed electron microscopic photographs using a computer. We confirmed that a mature HIV-1 particle had two copies of RNA strands in a cone-shaped core. These two RNA strands formed a coiling structure and interwound each other, and were already present in the late budding stage.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Takasaki T,Kurane I,Aihara H,Ohkawa N,Yamaguchi J

doi

10.1007/s007050050083

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

375-82

issue

2

eissn

0304-8608

issn

1432-8798

journal_volume

142

pub_type

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