Comparative analysis of rabies virus isolates from Brazilian canids and bats based on the G gene and G-L intergenic region.

Abstract:

:Rabies virus (RABV) isolates from two species of canids and three species of bats were analyzed by comparing the C-terminal region of the G gene and the G-L intergenic region of the virus genome. Intercluster identities for the genetic sequences of the isolates showed both regions to be poorly conserved. Phylogenetic trees were generated by the neighbor-joining and maximum parsimony methods, and the results were found to agree between the two methods for both regions. Putative amino acid sequences obtained from the G gene were also analyzed, and genetic markers were identified. Our results suggest that different genetic lineages of RABV are adapted to different animal species in Brazil.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Carnieli P Jr,Fahl Wde O,Brandão PE,Oliveira Rde N,Macedo CI,Durymanova E,Castilho JG

doi

10.1007/s00705-010-0671-7

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

941-8

issue

6

eissn

0304-8608

issn

1432-8798

journal_volume

155

pub_type

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