Preparation and characterization of a neutralizing monoclonal antibody directed to VP4 of rotavirus strain K8 which has unique VP4 neutralization epitopes.

Abstract:

:For selecting the neutralizing monoclonal antibodies (N-MAbs) directed to VP4 of rotavirus strain K8, which has unique VP4 neutralization epitopes, we prepared several reassortant viruses by mixed infection of two different strains K8 (serotype 1) and P (serotype 3) in vitro: three reassortant clones having VP4 of K8 and VP7 of P and four clones having VP4 of P and VP7 of K8. By using these reassortants in screening hybridomas, a N-MAb (K8-2C12) directed to strain K8-specific VP4 was obtained. The MAb K8-2C12 neutralized only K8 when tested against numerous strains of different serotypes, while in enzyme-linked immunosorbent assay this MAb reacted also with simian rotavirus SA11 (serotype 3), bovine rotavirus NCDV (serotype 6), and human rotavirus (HRV) strain 69M (serotype 8). Neutralization-resistant mutants of K8 were selected by the K8-2C12 antibody and VP4 amino acid sequences of the mutants were determined. Single amino acid substitution was detected in the three mutant clones at position 394, which is included in the major cross-reactive neutralization region identified in other rotaviruses.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Kobayashi N,Taniguchi K,Urasawa T,Urasawa S

doi

10.1007/BF01316751

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

153-62

issue

1-4

eissn

0304-8608

issn

1432-8798

journal_volume

121

pub_type

杂志文章
  • Isolation of avian influenza viruses from two different transhemispheric migratory shorebird species in Australia.

    abstract::Shorebirds on their southerly migration from Siberia to Australia, may pass through Asian regions currently experiencing outbreaks of highly pathogenic H5N1 influenza. To test for the presence of avian influenza viruses in migratory shorebirds arriving in Australia during spring 2004, 173 cloacal swabs were collected ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-006-0784-1

    authors: Hurt AC,Hansbro PM,Selleck P,Olsen B,Minton C,Hampson AW,Barr IG

    更新日期:2006-11-01 00:00:00

  • Variations in the core region of hepatitis C virus genomes in patients with chronic hepatitis.

    abstract::In each infected patient, the population of hepatitis C virus is composed of quasispecies that differ in their nucleotide sequences. Among regions in hepatitis C virus genomes, nucleotide sequences of the hypervariable region have been shown to change quickly during the course of infection. It is not known, however, w...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01315417

    authors: Kurosaki M,Enomoto N,Marumo F,Sato C

    更新日期:1995-01-01 00:00:00

  • Analysis of BK virus-transformed cells and BK virus-induced tumors by DNA-DNA reassociation kinetics.

    abstract::BK virus (BKV)-transformed cells and BKV-induced tumors as well as in vitro derived tumor cell lines were all found to contain BKV DNA sequences when analysed by DNA-DNA reassociation kinetics. In transformed cells the number of viral genome equivalents per diploid cell genome (CG divided by VG) decreased with increas...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01314838

    authors: Grossi MP,Corallini A,Poli F,Valieri A,Milanesi G,Barbanti-Brodano G

    更新日期:1981-01-01 00:00:00

  • B-cell activation in cats with feline infectious peritonitis (FIP) by FIP-virus-induced B-cell differentiation/survival factors.

    abstract::It has been suggested that antibody overproduction plays a role in the pathogenesis of feline infectious peritonitis (FIP). However, only a few studies on the B-cell activation mechanism after FIP virus (FIPV) infection have been reported. The present study shows that: (1) the ratio of peripheral blood sIg(+) CD21(-) ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-008-0265-9

    authors: Takano T,Azuma N,Hashida Y,Satoh R,Hohdatsu T

    更新日期:2009-01-01 00:00:00

  • Influence of immunosuppressive treatment of Borna Disease in rabbits.

    abstract::A total of 72 Borna Disease virus infected rabbits were treated with different concentrations of cyclophosphamide, glucocorticoids or both in combination. Comparison with untreated, infected rabbits showed a drastic alteration in the clinical picture, a considerable prolongation of the survival time, and differences i...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01318132

    authors: Gierend M,Ludwig H

    更新日期:1981-01-01 00:00:00

  • IgM fluorescence antibodies in sera of pregnant women exposed to rubella.

    abstract::A high per cent of false positive results for rubella virus IgM antibodies determined by immune fluorescence were detected in sera of pregnant women. After absorption with Staphylococcus suspension, Cowan 1 strain, and aggregates of human immunoglobulins, the false positive reactions due to IgM antiimmunoglobulin were...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01348028

    authors: Jankowski MA,Gut W,Switalski L,Imbs D,Kańtoch M

    更新日期:1979-01-01 00:00:00

  • Effect of gene constellation and postreassortment amino acid change on the phenotypic features of H5 influenza virus reassortants.

    abstract::Reassortants between a low-pathogenic avian influenza virus strain A/Duck/Primorie/2621/2001 (H5N2) and a high-yield human influenza virus strain A/Puerto Rico/8/34 (H1N1) were generated, genotyped and analyzed with respect to their yield in embryonated chicken eggs, pathogenicity for mice, and immunogenicity. A reass...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-006-0931-8

    authors: Rudneva IA,Timofeeva TA,Shilov AA,Kochergin-Nikitsky KS,Varich NL,Ilyushina NA,Gambaryan AS,Krylov PS,Kaverin NV

    更新日期:2007-01-01 00:00:00

  • Diversity of partial RNA-dependent RNA polymerase gene sequences of soybean blotchy mosaic virus isolates from different host-, geographical- and temporal origins.

    abstract::Infection of soybean by the plant cytorhabdovirus soybean blotchy mosaic virus (SbBMV) results in significant yield losses in the temperate, lower-lying soybean production regions of South Africa. A 277 bp portion of the RNA-dependent RNA polymerase gene of 66 SbBMV isolates from different: hosts, geographical locatio...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-018-3722-0

    authors: Strydom E,Pietersen G

    更新日期:2018-05-01 00:00:00

  • Effectiveness of first-line antiretroviral therapy in HIV/AIDS patients: A 5-year longitudinal evaluation in Fujian Province, Southeast China.

    abstract::The aim of this study was to evaluate the long-term effectiveness of first-line antiretroviral therapy in HIV/AIDS patients in Southeast China. A total of 450 eligible patients were selected to initiate first-line antiretroviral therapy from February 2005 through August 2009. During the study period from 2009 through ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-015-2583-z

    authors: Wu S,Qiu Y,Yan P,Wang W,Xie M,Xia P,Wang Z,Yan Y

    更新日期:2015-11-01 00:00:00

  • Contact infection of mink with 5 subtypes of avian influenza virus. Brief report.

    abstract::Avian influenza viruses of H3N8, H11N4, H7N7, H8N4, and H5N3 infected mink by contact. ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01309274

    authors: Okazaki K,Yanagawa R,Kida H

    更新日期:1983-01-01 00:00:00

  • Characterization of a genetic and antigenic variant of avian paramyxovirus 6 isolated from a migratory wild bird, the red-necked stint (Calidris ruficollis).

    abstract::A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8- and 16-fold difference, respectively, in their titers. The full genome se...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-014-2162-8

    authors: Bui VN,Mizutani T,Nguyen TH,Trinh DQ,Awad SS,Minoungou GL,Yamamoto Y,Nakamura K,Saito K,Watanabe Y,Runstadler J,Huettmann F,Ogawa H,Imai K

    更新日期:2014-11-01 00:00:00

  • Columbid circoviruses detected in free ranging pigeons from Southern Brazil: insights on PiCV evolution.

    abstract::Pigeon circovirus (PiCV) is taxonomically classified as a member of the Circovirus genus, family Circoviridae. The virus contains a single stranded DNA genome of approximately 2 kb, with minor length variations among different isolates. The occurrence of PiCV infections in pigeons (Columba livia) has been documented w...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-018-3990-8

    authors: Loiko MR,Junqueira DM,Varela APM,Tochetto C,Scheffer CM,Lima DA,Morel AP,Cerva C,Paim WP,Mayer FQ,Roehe PM

    更新日期:2018-11-01 00:00:00

  • An outbreak of echovirus 33 in schools in China in 2013.

    abstract::Echovirus 33 (E33) has been infrequently detected and is less frequently associated with clinical diseases when compared with other types of enteroviruses (EVs) in China. An outbreak of E33 was identified in four schools in Hunan Province, China, in June 2013. For laboratory diagnosis, throat swabs and/or serum specim...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-014-2059-6

    authors: Tan X,Gao L,Ma X,Nie J,Zhan D,Zhang B,Liu Y,Liu F,Xu W

    更新日期:2014-09-01 00:00:00

  • First detection and genetic characterization of a novel kirkovirus from a dead thoroughbred mare in northern Xinjiang, China, in 2018.

    abstract:BACKGROUND:In May 2018, a 8 year old thoroughbred mare died at an equestrian club in Changji, Xinjiang, China. The horse had been imported from the United States in 2013. She became pregnant in December 2016 but, after foaling, gradually lost weight and died in May 2018. This study aim to identify the pathogen, who cau...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04487-4

    authors: Xie J,Tong P,Zhang A,Yan Y,Zhang L,Song X,Chen J,Zhai S,Shaya N,Wang D,Su Z,Kuang L

    更新日期:2020-02-01 00:00:00

  • Characterization of a member of a new Potyvirus species infecting arracacha in Brazil.

    abstract::An arracacha (Arracacia xanthorrhiza) plant collected in Brazil was found to be infected by a new virus. This viral isolate (named C17) systemically infected Nicotiana benthamiana and Apium graveolens. A polyclonal antibody was raised, and analysis of our arracacha germplasm collection showed a high infection rate of ...

    journal_title:Archives of virology

    pub_type: 杂志文章,评审

    doi:10.1007/s00705-008-0289-1

    authors: Orílio AF,Dusi AN,Madeira NR,Inoue-Nagata AK

    更新日期:2009-01-01 00:00:00

  • Establishment of a feline T-lymphoblastoid cell line highly sensitive for replication of feline immunodeficiency virus.

    abstract::Interleukin-2 dependent feline T-lymphoblastoid cells designated as MYA-1 cells were established. The cells were free from exogenous retroviruses and sensitive for replication of feline immunodeficiency virus (FIV). FIV can grow more efficiently in MYA-1 cells than in feline primary peripheral blood mononuclear cells....

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01313750

    authors: Miyazawa T,Furuya T,Itagaki S,Tohya Y,Takahashi E,Mikami T

    更新日期:1989-01-01 00:00:00

  • Genomic analysis of bacteriophage ESP2949-1, which is virulent for Cronobacter sakazakii.

    abstract::Virulent phage ESP2949-1, which was isolated from sewage, has an icosahedral head, a contractile tail, and a double-stranded DNA genome with a length of 49,116 bp with 50.09% G+C content. Phage ESP2949-1 showed 3% similarity to enterobacteria phage TLS. Bioinformatics analysis of the phage genome revealed 43 putative ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-011-1147-0

    authors: Lee YD,Kim JY,Park JH,Chang H

    更新日期:2012-01-01 00:00:00

  • Latent herpesvirus infection of testes and spinal ganglia of turkeys with semen abnormalities.

    abstract::The present study confirms that herpesviruses (LF) previously isolated from testes and buffy coat cells of male turkeys with semen abnormalities establish a latent infection in testicular cells. These experiments also present the first evidence that these herpesviruses are harbored latently in cells of spinal ganglia....

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01311163

    authors: Benfield DA,Adldinger HK

    更新日期:1984-01-01 00:00:00

  • Seasonal distribution and epidemiological characteristics of human metapneumovirus infections in pediatric inpatients in Southeast China.

    abstract::Human metapneumovirus (hMPV) is an important respiratory pathogen in young children whose seasonal activity varies substantially from year to year among different populations. This study was conducted to investigate if there was a seasonal variation in the incidence of hMPV infection in young children and possible ass...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-012-1492-7

    authors: Wang Y,Chen Z,Yan YD,Guo H,Chu C,Liu J,Ding Y,Shao X,Xu J,Ji W

    更新日期:2013-02-01 00:00:00

  • Antigenic relationships between rotaviruses from different species as studied by neutralization and immunofluorescence.

    abstract::Antigenic relationships between the Wa, Hochi, Ito, Hosokawa and Nemoto strains of human rotavirus, the SA-11 strain of simian rotavirus, the Lincoln strain of bovine rotavirus, the OSU strain of porcine rotavirus and the R-2 strain of lapine rotavirus, which were all established in cell culture, were studied by neutr...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01341726

    authors: Sato K,Inaba Y,Miura Y,Tokuhisa S,Matumoto M

    更新日期:1982-01-01 00:00:00

  • Human papillomavirus type 16 E5 protein localizes to the Golgi apparatus but does not grossly affect cellular glycosylation.

    abstract::The E5 protein of papillomaviruses is a strongly hydrophobic membrane protein that can associate with the 16 kDa protein subunit of the vacuolar proton ATPase in endosomes and the Golgi apparatus resulting in raise of intraorganelle pH. We demonstrate that E5 of human papillomavirus type 16 (HPV16) when transfected in...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050070048

    authors: Oetke C,Auvinen E,Pawlita M,Alonso A

    更新日期:2000-01-01 00:00:00

  • Genome activation in alfamo- and ilarviruses.

    abstract::Alfamo- and ilarviruses are characterized by the deficiency of their genomes (three messenger-sense RNAs) to start an infection cycle. The RNAs are in capsids built from a single species of protein of about 24 kD. A few dimers of this coat protein per RNA molecule are sufficient to activate the genome. Since the first...

    journal_title:Archives of virology

    pub_type: 杂志文章,评审

    doi:10.1007/s007050050551

    authors: Jaspars EM

    更新日期:1999-01-01 00:00:00

  • Antigenic diversity of Norwalk-like viruses: expression of the capsid protein of a genogroup I virus, distantly related to Norwalk virus.

    abstract::The gene encoding the capsid protein of a genogroup I Norwalk-like virus (NLV) (Hu/NLV/Stav/95/Nor) was cloned and expressed in insect cells using a baculovirus vector. The His-tagged recombinant capsid protein (rStav) was antigenic and immunogenic, showed an apparent molecular weight of approximately 68 kD in protein...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050050665

    authors: Myrmel M,Rimstad E

    更新日期:2000-01-01 00:00:00

  • Characterisation of an Indonesian very virulent strain of infectious bursal disease virus.

    abstract::An Indonesian very virulent (vv) strain of infectious bursal disease virus (IBDV), designated Tasik94, was characterised both in vivo and at the molecular level. Inoculation of Tasik94 into 5-week-old specific-pathogen-free (SPF) chickens resulted in 100% morbidity and 45% mortality. The complete nucleotide and predic...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-002-0817-3

    authors: Rudd MF,Heine HG,Sapats SI,Parede L,Ignjatovic J

    更新日期:2002-07-01 00:00:00

  • A new sequence variant of Coleus blumei viroid 3 from the Coleus blumei cultivar 'Fairway Ruby'.

    abstract::A viroid was isolated from symptomless Coleus blumei cultivar (cv) 'Fairway Ruby' plants using the bidirectional PAGE method for analysis of small circular RNA molecules. The viroid was transmitted to viroid-free plants of Coleus blumei cv. 'Scarlet Dragonfly' by mechanical inoculation. Cloning and sequencing revealed...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01718241

    authors: Spieker RL,Marinkovic S,Sänger HL

    更新日期:1996-01-01 00:00:00

  • Inhibition of human immunodeficiency virus (HIV) type 1 multiplication by an avian cellular factor.

    abstract::A factor secreted from avian cells infected non productively with a non cytopathogenic mutant of vesicular stomatitis virus (VSV ts 1026) interferes with HIV replication in CEM cells and peripheral blood monocytes (PBL). Production of infectious particles is decreased and many virions lack cores and/or spikes. In CEM ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01317266

    authors: Semmel M,Alileche A,Coulaud D,Aguilar J,Krief P,Jasmin C

    更新日期:1992-01-01 00:00:00

  • Experimental induction of mucosal disease: consequences of superinfection of persistently infected cattle with different strains of cytopathogenic bovine viral diarrhea virus.

    abstract::Mucosal disease (MD) can be induced in cattle persistently infected with noncytopathogenic bovine viral diarrhea virus (ncp BVD virus) by superinfecting them with antigenically related cytopathogenic (cp) BVD virus strains. While some of these animals succumb to early onset MD after 2 to 3 weeks post infectionem (p.i....

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050050322

    authors: Loehr BI,Frey HR,Moennig V,Greiser-Wilke I

    更新日期:1998-01-01 00:00:00

  • Persistent baculovirus infections: Spodoptera frugiperda NPV and Autographa californica NPV in Spodoptera frugiperda cells.

    abstract::Establishment of a persistent infection of Spodoptera frugiperda nuclear polyhedrosis virus (NPV) in Spodoptera frugiperda (S.f.) cells occurred in three phases: the first phase was characterised by high levels of cell infection and death, the second phase by decreasing cell infection levels leading to the final phase...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01310859

    authors: Crawford AM,Sheehan C

    更新日期:1983-01-01 00:00:00

  • Phylogenetic analysis of porcine reproductive and respiratory syndrome virus isolates from Northern Ireland.

    abstract::To investigate the genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) in Northern Ireland, the ORF5 gene from nine field isolates was sequenced and phylogenetically analysed. The results revealed relatively high diversity amongst isolates, with 87.6-92.2% identity between farms at the nuc...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-018-3886-7

    authors: Smith N,Power UF,McKillen J

    更新日期:2018-10-01 00:00:00

  • The glycoprotein nature of murine gamma interferon.

    abstract::Synthesis of murine gamma interferon (MuIFN gamma) by phytohemagglutinin (PHA)-stimulated spleen cells was inhibited in a dose-dependent manner by graded concentrations of tunicamycin or 2-deoxy-glucose, both of which inhibit glycosylation. The homologous (murine) and heterologous (rat) antiviral activities of the MuI...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01310659

    authors: Havell EA,Spitalny GL

    更新日期:1984-01-01 00:00:00