Identification and full-length molecular characterization of rare hepatitis C virus genotype 5a from India.

Abstract:

:This report presents a molecular characterization of the complete genome of a rare hepatitis C virus (HCV) genotype (GT5a) from India. Sequence homology of full genome revealed that the strain belonged to HCV GT5a. To trace the origin of this virus and to understand its evolutionary pattern, a phylogenetic reconstruction was carried out on full HCV genome sequences using Bayesian coalescent methods. The phylogenetic tree reconstruction revealed genotypic divergence, with formation of distinct clades. This analysis revealed that HCV genotype 5 might have originated from HCV genotype 3, as they have a recent common ancestor.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Choudhary MC,Gupta E,Pandey P,Natarajan V,Sharma S,Vashishtha C,Sharma MK,Kazim SN,Sarin SK

doi

10.1007/s00705-014-2220-2

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

329-33

issue

1

eissn

0304-8608

issn

1432-8798

journal_volume

160

pub_type

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