Abstract:
:This report presents a molecular characterization of the complete genome of a rare hepatitis C virus (HCV) genotype (GT5a) from India. Sequence homology of full genome revealed that the strain belonged to HCV GT5a. To trace the origin of this virus and to understand its evolutionary pattern, a phylogenetic reconstruction was carried out on full HCV genome sequences using Bayesian coalescent methods. The phylogenetic tree reconstruction revealed genotypic divergence, with formation of distinct clades. This analysis revealed that HCV genotype 5 might have originated from HCV genotype 3, as they have a recent common ancestor.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Choudhary MC,Gupta E,Pandey P,Natarajan V,Sharma S,Vashishtha C,Sharma MK,Kazim SN,Sarin SKdoi
10.1007/s00705-014-2220-2subject
Has Abstractpub_date
2015-01-01 00:00:00pages
329-33issue
1eissn
0304-8608issn
1432-8798journal_volume
160pub_type
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