Abstract:
:The herpes simplex virus (HSV)-infected mouse model was used to correlate histopathological lesions in adrenal glands and ovaries with the localisation of viral nucleic acids and viral antigens, employing in situ hybridization and immunohistochemistry. In the adrenals, the lesions were mainly restricted to the zona fasciculata and the zona reticularis, sometimes extending to the medulla. In the ovaries, lesions were detected in follicles and in the stroma. During the course of infection, HSV nucleic acids could be detected earlier than HSV proteins. Next to the center of necrotic foci mainly HSV proteins were detected, whereas peripheral cells were found to contain viral nucleic acids. In situ hybridization revealed no proof of HSV latency in either organ. Among HSV-1 and HSV-2 strains of different neurovirulence, only HSV-2 variant ER- failed to replicate in adrenal glands and ovaries, whereas the neuroinvasive variant ER+ showed the same patterns as the HSV-1 strains used.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Wiegand H,Dienes HP,Schirmacher P,Podlech J,Bohl K,Bohle M,Neumann-Haefelin D,Falke Ddoi
10.1007/BF01310768subject
Has Abstractpub_date
1991-01-01 00:00:00pages
237-49issue
3-4eissn
0304-8608issn
1432-8798journal_volume
117pub_type
杂志文章abstract::Virulent phage ESP2949-1, which was isolated from sewage, has an icosahedral head, a contractile tail, and a double-stranded DNA genome with a length of 49,116 bp with 50.09% G+C content. Phage ESP2949-1 showed 3% similarity to enterobacteria phage TLS. Bioinformatics analysis of the phage genome revealed 43 putative ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1147-0
更新日期:2012-01-01 00:00:00
abstract::A xenotropic Moloney murine leukemia virus-derived recombinant retrovirus (MMuLVSVnlslacZ) has been utilized to study the mechanism of virus entry into endothelial and epithelial porcine cells. In the genome of this recombinant retrovirus, the nlslacZ reporter gene is under the transcriptional control of both LTR and ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314625
更新日期:1992-01-01 00:00:00
abstract::An F35L mutation in the N-terminal domain of the polymerase acidic protein (PA-Nter), which contains the active site of the endonuclease, has been reported to result in higher polymerase activity in mouse-adapted strains of the 2009 pandemic influenza A H1N1 virus. We modeled wild and mutant complexes of uridine 5'-mo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3681-x
更新日期:2018-04-01 00:00:00
abstract::Rabies is one of the most important zoonotic diseases and is caused by several rabies virus (RABV) variants. These variants can exhibit differences in neurovirulence, and few studies have attempted to evaluate the neuroinvasiveness of variants derived from vampire bats and wild carnivores. The aim of this study was to...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3530-y
更新日期:2017-12-01 00:00:00
abstract::In order to investigate the genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) strains currently circulating in the Republic of Ireland (ROI), the ORF5 gene from 17 field strains originating from four vaccinating commercial herds was sequenced and phylogenetically analysed. High genetic v...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04710-7
更新日期:2020-09-01 00:00:00
abstract::Serologic and virologic prevalence of infection with different swine influenza virus (SIV) subtypes was investigated using swine sera, nasal swabs and lung samples that had been submitted for a diagnosis to the Minnesota Veterinary Diagnostic Laboratory. A total of 111,418 pig sera were tested for SIV antibody between...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-002-0788-4
更新日期:2002-06-01 00:00:00
abstract::A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (2...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2742-2
更新日期:2016-04-01 00:00:00
abstract::Immunoblot analysis of apple latent spherical cheravirus (ALSV)-infected leaves using a polyclonal antibody against the 21 C-terminal amino acids of a 53 K/42 K movement protein (MP) showed that a protein with an Mr of 42 kDa (42KP) is the dominant form found in vivo, which could indicate that the second AUG is used a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-005-0689-4
更新日期:2006-05-01 00:00:00
abstract::Terminal sequences of the bi-segmented dsRNA genome of 3 different strains of infectious bursal disease virus (IBDV) were analyzed by the rapid amplification of cDNA 5' ends (5'RACE) procedure. Both segments are 85% homologous in a 32-nucleotide sequence comprising the 5' end, whereas the 3' end has a conserved pentam...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718616
更新日期:1996-01-01 00:00:00
abstract::In order to improve the knowledge of the humoral immune response to CMV infection, we developed an immunoblotting technique which allowed a better analysis of the changes in the pattern of anti CMV-polypeptides IgM. We examined 234 sera belonging to 27 renal allograft recipients developing a primary or recurrent CMV i...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310938
更新日期:1989-01-01 00:00:00
abstract::Seven dsRNA segments were detected from a single Rhizoctonia solani strain HG81. From the full-length cDNA sequences of four smaller dsRNA segments, the genomes of two related partitiviruses, designated as Rhizoctonia solani partitivirus 3 (RsPV3) and RsPV4, were determined. The genomes of RsPV3 and RsPV4 are both com...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3627-3
更新日期:2018-02-01 00:00:00
abstract::Antibody-like molecules consisting of the human CD 4 extracellular domain fused to human IgG1 heavy chain constant regions were genetically constructed and expressed in a BHK cell stable transfectant. Purified chimeric antibodies bound to HIV particles as it was shown by immuno electron microscopy, inhibited fusions o...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310503
更新日期:1990-01-01 00:00:00
abstract::Pigeon circovirus (PiCV) is taxonomically classified as a member of the Circovirus genus, family Circoviridae. The virus contains a single stranded DNA genome of approximately 2 kb, with minor length variations among different isolates. The occurrence of PiCV infections in pigeons (Columba livia) has been documented w...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-018-3990-8
更新日期:2018-11-01 00:00:00
abstract::Blot hybridization analysis of infected bovine herpesvirus 1 (BHV-1) cellular RNA isolated at various times post infection and after treatment with specific metabolic inhibitors was used to characterize transcription of the BHV-1 Cooper isolate. Synthesis of BHV-1 RNA was detected as early as 3 h post infection and re...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316744
更新日期:1991-01-01 00:00:00
abstract::Noninfectious virus particles were produced in Ehrlich ascites tumor cells infected intraperitoneally with fowl plague virus. The PFU yield of virus per cell was less than 0.1 and the ratio PFU/HA units in the progeny virus was less than 10(3). The virus particles had the same morphology and size as egg-grown virus bu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315278
更新日期:1978-01-01 00:00:00
abstract::After the first identification of tomato yellow leaf curl virus (TYLCV) in the southern part of Korea in 2008, TYLCV has rapidly spread to tomato farms in most regions of Korea. From 2008 to 2010, a survey of natural weed hosts that could be reservoirs of TYLCV was performed in major tomato production areas of Korea. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1913-2
更新日期:2014-06-01 00:00:00
abstract::The genome of yam virus X (YVX), a new member of the genus Potexvirus from yam (Dioscorea trifida), was completely sequenced. Structural and phylogenetic analysis showed that the closest relative of YVX is nerine virus X. A prevalence study found YVX only in plants maintained in Guadeloupe and showed that it also infe...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2211-3
更新日期:2014-12-01 00:00:00
abstract::Human cytomegalovirus (HCMV), oxidized by sodium periodate (NaIO4), is incapable of giving rise to viral progeny in cell culture. At a NaIO4 concentration as low as 5 mM, there is a loss of at least 6 logs of viral infectivity which occurs very rapidly (less than 5 min). Further, the inactivation is a first-order reac...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309765
更新日期:1994-01-01 00:00:00
abstract::The family Astroviridae consists of two genera, Avastrovirus and Mamastrovirus, whose members are associated with gastroenteritis in avian and mammalian hosts, respectively. We serendipitously identified a novel porcine astrovirus in a fecal specimen from a domestic pig (Sus scrofa domestica) in Hungary. Sequencing of...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0827-5
更新日期:2011-01-01 00:00:00
abstract::At low pH influenza virus causes membrane fusion. This phenomenon is thought to reflect a part of the infection mechanism of the virus. To obtain more information on the effect of low pH on the virus, the change in morphology of influenza virus particles was studied by electron microscopy. Further, the degradation of ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311162
更新日期:1984-01-01 00:00:00
abstract::Tobacco vein banding mosaic virus (TVBMV) is of increasing importance in tobacco production. Knowledge of the genetic structure and variability of the virus population is vital for developing sustainable management. In this study, 24 new TVBMV isolates from Sichuan Province together with 46 previous isolates were stud...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04342-6
更新日期:2019-10-01 00:00:00
abstract::The interaction between two different bovine respiratory syncytial virus (BRSV) strains and bovine alveolar macrophages (BAMs) was studied in vitro. Bovine respiratory syncytial virus replicated minimally in BAMs and most of the virus produced remained cell-associated. Approximately 1 out of 1,000 BAMs produced infect...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322681
更新日期:1995-01-01 00:00:00
abstract::The complement fixing antigens of rubella virus have been found to contain virion envelope but little nucleocapsid polypeptides. They are also shown to be associated with two additional polypeptides of host origin. Evidence is presented to suggest that the complement fixing antigens are structural components of the pl...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315301
更新日期:1986-01-01 00:00:00
abstract::The VP1 encoded by genomic segment B of birnaviruses is generally known to exist as a genome-linked protein (VPg) and as a "free" polypeptide of 90 kDa in virus particles. The guanylylation activity associated with infectious bursal disease virus (IBDV) was demonstrated by incubating purified virus in presence of [alp...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050154
更新日期:1997-01-01 00:00:00
abstract::The complete nucleotide sequence of genome segment S9, which was reported as the ninth largest among the 12 genome segments of rice dwarf virus, was determined. The segment was 1,305 bp long and coded for a protein composed of 351 amino acids (Mr 38,930). The terminal sequences of the segment were found to consist of ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313885
更新日期:1989-01-01 00:00:00
abstract::Non-structural as well as VP1 recombinant proteins of foot-and-mouth disease virus (FMDV) produced in E. coli, have been used to study the specific antibody response of infected or vaccinated swine. An analysis of sera from infected pigs, using a direct ELISA, showed that polypeptide 3ABC (spanning non-structural prot...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01538822
更新日期:1994-01-01 00:00:00
abstract::Canine enteric coronaviruses (CCoVs) are important enteric pathogens of dogs. CCoVs with different variations are typically pantropic and pathogenic in dogs. In this study, we isolated a CCoV, designated HLJ-073, from a dead 6-week-old male Pekingese with gross lesions and diarrhea. Interestingly, sequence analysis su...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04296-9
更新日期:2019-08-01 00:00:00
abstract::The stability of regions containing tandemly reiterated sequences in the S component of the herpes simplex virus type 1 (HSV-1) genome was determined, by comparing restriction fragments of the regions among sets of HSV-1 isolates derived from a single source. The 6 reiterations examined were grouped into three. Reiter...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313958
更新日期:1989-01-01 00:00:00
abstract::Porcine reproductive and respiratory syndrome (PRRS) is one of the most highly infectious diseases in the pig industry, resulting in enormous economic losses worldwide. In this study, a PRRS virus (PRRSV) strain was isolated from primary porcine alveolar macrophage cells in Xinjiang in northwest China. This new strain...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-019-04373-z
更新日期:2019-11-01 00:00:00
abstract::Classic neutralization studies by Fazekas de St. Groth and Webster (8) on mixtures of influenza viruses and mixtures of rabbit antisera are reinterpreted in terms of a percentage contaminant in the stock used for the dilution series. A very small amount of a different virus changes the shape of quantal assay curves co...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317497
更新日期:1979-01-01 00:00:00