The epidemiology of rotavirus disease in under-five-year-old children hospitalized with acute diarrhea in central Uganda, 2012-2013.

Abstract:

:A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (27 %, 55/204) and G12P[4] (18.6 %, 38/204). Mixed infections were detected in 22.5 % (46/204) of the children. The study suggests that consumption of raw vegetables (OR = 1.45, 95 % CI = 1.03-2.03) and family ownership of dogs (OR = 1.9, 95 % CI = 1.04-3.75) increases the risk of rotavirus infection. The study findings will be used to assess the impact of RV vaccination in Uganda.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Bwogi J,Malamba S,Kigozi B,Namuwulya P,Tushabe P,Kiguli S,Byarugaba DK,Desselberger U,Iturriza-Gomara M,Karamagi C

doi

10.1007/s00705-015-2742-2

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

999-1003

issue

4

eissn

0304-8608

issn

1432-8798

pii

10.1007/s00705-015-2742-2

journal_volume

161

pub_type

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