Abstract：
:At low pH influenza virus causes membrane fusion. This phenomenon is thought to reflect a part of the infection mechanism of the virus. To obtain more information on the effect of low pH on the virus, the change in morphology of influenza virus particles was studied by electron microscopy. Further, the degradation of haemagglutinin (HA) after trypsin digestion as a function of pH was studied by gel electrophoresis. The results showed that a threshold value existed below which both a change in morphology and an increase in trypsin sensitivity were observed. This threshold pH was found to be strain specific. A number of strains showed a heterogeneity in the particle population with respect to the threshold pH. The various subpopulations appeared to differ genetically. Virus particles with uncleaved precursor HA, HAo, were not effected by the low pH treatment.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Ruigrok RW,Cremers AF,Beyer WE,de Ronde-Verloop FMdoi
10.1007/BF01311162subject
Has Abstractpub_date
1984-01-01 00:00:00pages
181-94issue
3-4eissn
0304-8608issn
1432-8798journal_volume
82pub_type
杂志文章abstract：:A collection of 148 adenovirus strains of subgenus C collected in Argentina, Chile, and Uruguay were studied by restriction enzyme analysis of genomic DNA with endonucleases BamHI, BglII, BstEII, EcoRI, HindIII, KpnI, and SmaI. Only strains corresponding to serotypes 1, 2, and 5 were identified representing both alrea...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309841
更新日期：1993-01-01 00:00:00
abstract：:Receptor-mediated activation is accompanied by phospholipid metabolism and by calcium fluctuation resulting in a chemiluminescence (CL) response in the neutrophil. This pathway involves activation of protein kinase C (PKC) and the NADPH oxidase. Artificial stimulants such as phorbol esters, specifically 12-O-tetradeca...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310506
更新日期：1990-01-01 00:00:00
abstract：:Foot-and-mouth disease virus (FMDV) causes a highly contagious viral disease of cloven-hoofed animals, which has a considerable socio-economic impact on the countries affected. In addition, persistent infection can occur following clinical or sub-clinical disease in either vaccinated or non-vaccinated cattle. The mech...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0867-6
更新日期：2002-11-01 00:00:00
abstract：:Modern adjuvants should induce strong and balanced immune responses, and it is often desirable to induce specific types of immunity. As an example, efficient Th1-immunity-inducing adjuvants are highly in demand. Such adjuvants promote good cell-mediated immunity against subunit vaccines that have low immunogenicity th...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-010-0863-1
更新日期：2011-02-01 00:00:00
abstract：:Mycoviruses are viruses that infect fungi. Recently, mycovirus-like RNAs were sequenced from the fungus Phakopsora pachyrhizi, the causal agent of soybean rust. One of the RNAs appeared to represent a novel mycovirus and was designated Phakopsora pachyrhizi virus 2383 (PpV2383). The genome of PpV2383 resembles Sacchar...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2639-0
更新日期：2016-01-01 00:00:00
abstract：:The Chinese hog cholera lapinized virus (HCLV), also called the "Chinese strain" or "C-strain" of classical swine fever virus (CSFV), was developed in China in the 1950s. There are uncertainties about the genetic heterogeneity and origin of this vaccine virus. The objectives of this study were to investigate the genet...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-0948-5
更新日期：2011-06-01 00:00:00
abstract：:Cultures from pig bone marrow cells were infected with ASFV and the replication cycle was studied. In the cytoplasmic replication areas there are a differentiation of membrane segments. Some of them are polygonal, which give rise to virus particles. An over production of viral coded materials, including non-polygonal ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF02175596
更新日期：1975-01-01 00:00:00
abstract：:Few reports are available on HCV molecular epidemiology among IDUs in Eastern Europe, and none in Montenegro. The aim of this study was to investigate the HCV genotype distribution in Montenegro among IDUs and to perform Bayesian and evolutionary analysis of the most prevalent HCV genotype circulating in this populati...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3224-5
更新日期：2017-06-01 00:00:00
abstract：:Bovine leukemia virus (BLV) causes enzootic bovine leucosis (EBL) and is responsible for substantial economic losses in cattle globally. However, information in Africa on the disease is limited. Here, based on clinical, hematological, pathological and molecular analyses, two clinical cases of EBL were confirmed in a d...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3205-0
更新日期：2017-04-01 00:00:00
abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) causes a variety of cancers, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). Host cellular microRNAs (miRNAs) play important post-transcriptional regulatory roles in gene expression and can greatly influence viru...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3478-y
更新日期：2017-11-01 00:00:00
abstract：:An electron microsopic study of cell cultures and bovine foetal tracheal organ cultures infected with infectious bovine rhinotracheitis (IBR) virus showed the following. a) The difference in the site at which the outer envelope is acquired in the infected cell is responsible for some morphological differences between ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317842
更新日期：1976-01-01 00:00:00
abstract：:TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-like mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% preva...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s705-002-8310-6
更新日期：2002-01-01 00:00:00
abstract：:Broadly neutralizing antibodies (bNAbs) are very promising agents for HIV-1 prophylaxis and AIDS treatment. However, the neutralization susceptibility of circulating recombinants such as CRF01_AE, which is becoming increasingly prevalent, has not been studied in detail until now. Here, we focused on CRF01_AE in China ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-4011-7
更新日期：2018-12-01 00:00:00
abstract：:The complete nucleotide sequence (4838 nucleotides) of Iris yellow spot virus (IYSV) M RNA indicates, typical for tospoviruses, the presence of two genes in ambisense arrangement. The vRNA ORF codes for the potential cell-to-cell movement (NSm) protein (34.8 kDa) and the vcRNA ORF for the viral glycoprotein (G1/G2) pr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0885-4
更新日期：2002-12-01 00:00:00
abstract：:Human cytomegalovirus (HCMV), oxidized by sodium periodate (NaIO4), is incapable of giving rise to viral progeny in cell culture. At a NaIO4 concentration as low as 5 mM, there is a loss of at least 6 logs of viral infectivity which occurs very rapidly (less than 5 min). Further, the inactivation is a first-order reac...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309765
更新日期：1994-01-01 00:00:00
abstract：:Chikungunya fever is self-limiting. However, neurological and hemorrhagic complications have been seen in recent outbreaks. The clinical manifestations of this disease are similar to those of dengue virus infection, indicating the need for differential diagnosis in areas such as India, which are endemic for both virus...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2829-4
更新日期：2016-06-01 00:00:00
abstract：:Molecular variability was assessed for 18 isolates of cowpea mild mottle virus (CPMMV, genus Carlavirus, family Betaflexiviridae) found infecting soybean in various Brazilian states (Bahia, Goiás, Maranhão, Mato Grosso, Minas Gerais, Pará) in 2001 and 2010. A variety of symptoms was expressed in soybean cv. CD206, ran...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1879-0
更新日期：2014-04-01 00:00:00
abstract：:The C-terminal R peptide of ecotropic murine leukemia virus (MLV) envelope protein (Env) negatively controls membrane fusion activity. The R peptide cleavage during virion maturation activates its fusogenicity and is required for viral entry. We analyzed fusogenicity and transduction efficiency of mutant Env proteins ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1054-6
更新日期：2007-01-01 00:00:00
abstract：:Yellow fever was presumably imported to the Americas from West-Africa from the 16th to the 19th century. American and African genotypes of the virus are distinguishable, indicating separate evolution in different vector/host cycles. The complete nucleotide sequence of the yellow fever virus strain TRINID79A, isolated ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050708
更新日期：1999-01-01 00:00:00
abstract：:Analysis of a loquat tree with leaf curl symptoms by deep sequencing revealed a novel virus with a single-stranded RNA genome, for which the name "loquat virus A" (LoVA) was proposed. The complete genome sequence comprised 7553 nucleotides (nt) and an additional poly(A) tail at the 3' terminus. Sequence comparisons of...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04444-1
更新日期：2020-01-01 00:00:00
abstract：:The DNA of mammalian cells treated with 4,5',8-trimethylpsoralen (Trioxsalen) is crosslinked (preventing transcription) only after photoactivation with near ultraviolet light. Suppression of gene action in cocultivated or fused cultures, including both induction and antiviral action of fibroblast interferon, can conse...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320762
更新日期：1980-01-01 00:00:00
abstract：:We discovered a soybean mosaic virus (SMV) variant (4278-1) that caused systemic infections in Nicotiana benthamiana plants, resulting in stem stunting and leaf shriveling. The virus had a particle morphology and incubation period similar to those of other SMV isolates but differed from them in the leaf symptoms it ca...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3123-1
更新日期：2017-02-01 00:00:00
abstract：:The complete genomes of a monopartite begomovirus (genus Begomovirus, family Geminiviridae) and an associated betasatellite found infecting Vernonia amygdalina Delile (family Compositae) in Uganda were cloned and sequenced. Begomoviruses isolated from two samples showed the highest nucleotide sequence identity (73.1% ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3175-2
更新日期：2017-04-01 00:00:00
abstract：:For selecting the neutralizing monoclonal antibodies (N-MAbs) directed to VP4 of rotavirus strain K8, which has unique VP4 neutralization epitopes, we prepared several reassortant viruses by mixed infection of two different strains K8 (serotype 1) and P (serotype 3) in vitro: three reassortant clones having VP4 of K8 ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316751
更新日期：1991-01-01 00:00:00
abstract：:A potyvirus from Chinese narcissus was transmitted mechanically to three species of Narcissus and to Lycoris radiata but not to 22 other test species. In western blot, the coat protein reacted strongly with Narcissus degeneration virus (UK isolate) antiserum. Antiserum raised to the Chinese virus did not react with ei...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0841-9
更新日期：2007-02-01 00:00:00
abstract：:Antibody-like molecules consisting of the human CD 4 extracellular domain fused to human IgG1 heavy chain constant regions were genetically constructed and expressed in a BHK cell stable transfectant. Purified chimeric antibodies bound to HIV particles as it was shown by immuno electron microscopy, inhibited fusions o...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310503
更新日期：1990-01-01 00:00:00
abstract：:The temperature sensitivity of herpes simplex virus type 1 (HSV-1) was assessed in primary cultures of mouse central nervous system (MNS) cells and mouse embryo cells (MEC). Infectious yields were determined and the ultrastructural morphogenesis of HSV-1 particles was compared following incubation at 37 or 40.5 degree...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309574
更新日期：1992-01-01 00:00:00
abstract：:A total of 34 highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) strains isolated from Vietnam during 2013-2014 were sequenced and analyzed. A partial sequence of ORF1a corresponding to the nonstructural protein 2 (Nsp2) coding region and the full sequence of open reading frame 5 (ORF5) g...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2699-1
更新日期：2016-03-01 00:00:00
abstract：:Coxsackievirus B3 (CV-B3) has frequently been associated with aseptic meningitis outbreaks in China. To identify sequence motifs related to aseptic meningitis and to construct an infectious clone, the genome sequence of 08TC170, a representative strain isolated from cerebrospinal fluid (CSF) samples from an outbreak i...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2893-9
更新日期：2016-08-01 00:00:00
abstract：:Retrovirus infectivity is the result of a cooperative interaction of three structural genes, gag, pol, and env. Since the L-cell endogenous retrovirus (LCV) lacks the env gene translation product, our aim was to study the biological and molecular basis of its non-infectiousness. Fusion experiments between LCV and homo...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315566
更新日期：1988-01-01 00:00:00
