Abstract：
:Modern adjuvants should induce strong and balanced immune responses, and it is often desirable to induce specific types of immunity. As an example, efficient Th1-immunity-inducing adjuvants are highly in demand. Such adjuvants promote good cell-mediated immunity against subunit vaccines that have low immunogenicity themselves. The development of such adjuvants may take advantage of the increased knowledge of the molecular mechanisms and factors controlling these responses. However, knowledge of such molecular details of immune mechanisms is relatively scarce for species other than humans and laboratory rodents, and in addition, there are special considerations pertaining to the use of adjuvants in veterinary animals, such as production and companion animals. With a focus on veterinary animals, this review highlights a number of approaches being pursued, including cytokines, CpG oligonucleotides, microparticles and liposomes.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Heegaard PM,Dedieu L,Johnson N,Le Potier MF,Mockey M,Mutinelli F,Vahlenkamp T,Vascellari M,Sørensen NSdoi
10.1007/s00705-010-0863-1subject
Has Abstractpub_date
2011-02-01 00:00:00pages
183-202issue
2eissn
0304-8608issn
1432-8798journal_volume
156pub_type
杂志文章,评审abstract：:Bohle iridovirus (BIV) belongs to the genus Ranavirus, of which Frog virus 3 (FV-3) is the type species. We are developing BIV as a recombinant viral delivery vector, and as a first step we located specific BIV promoter sequences to drive foreign gene expression in the recombinant virus. By comparison with FV-3 sequen...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0532-y
更新日期：2005-09-01 00:00:00
abstract：:The complete genome sequence (9,865 nucleotides) of a highly divergent johnsongrass mosaic virus isolate (JGMV-CNPGL) was determined using Illumina sequencing. This isolate infected 10 genotypes of gramineous plants including maize. A comparative analysis of the complete genome showed 80 % nucleotide (nt) sequence ide...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2832-9
更新日期：2016-07-01 00:00:00
abstract：:Rotavirus (RV) is the primary cause of severe dehydrating gastroenteritis and acute diarrheal disease in infants and young children. Previous studies have revealed that genistein can inhibit the infectivity of enveloped or nonenveloped viruses. Although the biological properties of genistein are well studied, the mech...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2404-4
更新日期：2015-06-01 00:00:00
abstract：:Complete nucleotide sequences of three strains (I, III, and IV) of Barley yellow mosaic virus (BaYMV) isolated in Japan were determined. The length of the genome was the same among the three strains; RNA1 was 7,642 nt and RNA2 was 3,585 nt. The molecular phylogenetic analysis showed that strain I was most closely rela...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0163-1
更新日期：2008-01-01 00:00:00
abstract：:The complete nucleotide sequence of Subterranean clover mottle virus (SCMoV) genomic RNA has been determined. The SCMoV genome is 4,258 nucleotides in length. It shares most nucleotide and amino acid sequence identity with the genome of Lucerne transient streak virus (LTSV). SCMoV RNA encodes four overlapping open rea...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0144-3
更新日期：2003-11-01 00:00:00
abstract：:The effects of relative humidity and temperature on the survival of human rotavirus in a thin layer of faeces on an impervious surface and on absorbent material was investigated using the indirect immunofluorescence technique in LLC-MK2 cells to titrate infectivity. Rotavirus was found to be very stable at low and hig...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01348963
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-4056-7
更新日期：2019-01-01 00:00:00
abstract：:The objectives of this study were to determine the antigenic relationship among ruminant adenoviruses and determine their phylogenetic relationship based on the deduced hexon gene amino acid sequence. Results of reciprocal cross-neutralization tests demonstrated antigenic relationships in either one or both directions...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0063-4
更新日期：2008-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04670-y
更新日期：2020-09-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3716-y
更新日期：2018-05-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1552-z
更新日期：2013-07-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1460-2
更新日期：2013-01-01 00:00:00
abstract：:The ability of lymphocytes from patients with multiple sclerosis (MS) to produce Interferon (IFN-alpha) in response to Newcastle Disease Virus (NDV) was studied in vitro. The correlation between individual IFN-alpha titers and natural killer (NK) cell activity and the presence of HLA system antigens associated with MS...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314877
更新日期：1982-01-01 00:00:00
abstract：:Viral infections of the central nervous system (CNS) following peripheral inoculation of Sindbis viruses were studied. The use of viral strains, which vary in their neuroinvasive and neurovirulent properties, and various strains of mice, which differ in immunocompetence, revealed several pathways of viral neuroinvasio...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050576
更新日期：1999-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2162-8
更新日期：2014-11-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-04137-1
更新日期：2019-03-01 00:00:00
abstract：:During infection with herpes simplex virus type 1 (HSV-1) the activity of tyrosine hydroxylase (TH) in PC12 pheochromocytoma cells was initially depressed reaching a nadir at 6 hours post-inoculation, but recovered rapidly with a return to baseline activity by 8 to 9 hours post-inoculation. Subsequently, TH activity a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310965
更新日期：1985-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322691
更新日期：1995-01-01 00:00:00
abstract：:Transgenic plants represent an inexpensive alternative to classical fermentation systems for production of recombinant subunit vaccines. Transgenic potato plants were created that express the N-terminal domain of the glycoprotein S (N-gS) from Transmissible gastroenteritis coronavirus (TGEV), containing the major anti...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070087
更新日期：2000-01-01 00:00:00
abstract：:Cultures from pig bone marrow cells were infected with ASFV and the replication cycle was studied. In the cytoplasmic replication areas there are a differentiation of membrane segments. Some of them are polygonal, which give rise to virus particles. An over production of viral coded materials, including non-polygonal ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF02175596
更新日期：1975-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1480-y
更新日期：2013-01-01 00:00:00
abstract：:Many distinct polyomaviruses infecting a variety of vertebrate hosts have recently been discovered, and their complete genome sequence could often be determined. To accommodate this fast-growing diversity, the International Committee on Taxonomy of Viruses (ICTV) Polyomaviridae Study Group designed a host- and sequenc...
journal_title：Archives of virology
pub_type： 新闻
doi：10.1007/s00705-016-2794-y
更新日期：2016-06-01 00:00:00
abstract：:Non-nucleoside reverse transcriptase inhibitors (NNRTIs) act quite specifically on human immunodeficiency virus type 1 (HIV-1). In general, they are not effective on human immunodeficiency virus type 2 (HIV-2) or simian immunodeficiency virus (SIV). Only SIV strains from African green monkeys are sensitive to several ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070003
更新日期：2000-01-01 00:00:00
abstract：:Lymphocytic chorimeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), causative agent of Lassa hemorrhagic fever (LHF), belong to the Old World group of the family Arenaviridae. Both viruses have extensive strain diversity and significant variations in lethality and pathogenicity for man and expe...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0385-9
更新日期：2004-12-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0031-4
更新日期：2008-01-01 00:00:00
abstract：:A potyvirus isolated from Pinellia ternata in China was characterised and shown to be related to Soybean mosaic virus (SMV). The virus was pathogenic on P. ternata and some soybean cultivars, whereas the local soybean SMV isolate HH5 did not infect P. ternata. Western blot experiments demonstrated a serological relati...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0184-8
更新日期：2004-02-01 00:00:00
abstract：:Treatment of Cricket paralysis virus infected Drosophila cells with iodoacetamide before radiolabelling with 35S-methionine results in the appearance of two high molecular weight polypeptides of approximately equal to 200,000 molecular weight, not apparent in untreated infected cells (17). To attempt to differentiate ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320788
更新日期：1981-01-01 00:00:00
abstract：:The long distance movement of potyviruses is a poorly understood step of the viral cycle. Only factors inhibiting this process, referred to as "Restricted TEV Movement" (RTM), have been identified in Arabidopsis thaliana. On the virus side, the potyvirus coat protein (CP) displays determinants required for long-distan...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3292-6
更新日期：2017-07-01 00:00:00
abstract：:Cellular uptake of fowl plague virus occurs 10-30 minutes after inoculation of chick embryo cells. The penetration of the virions is by pinocytosis (viropexis); fusion with the cellular membrane has not been observed. After pinocytosis the virions become gradually disintegrated. Budding of newly formed virions from th...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317537
更新日期：1975-01-01 00:00:00
abstract：:A new bisegmented dsRNA virus has been detected in shoots of blue spruce with bud blight disease symptoms and infection by Cucurbitaria piceae (Bortw.) fungus. The virus genome consists of two segments that are 2071 and 2257 nt long, encoding the putative RNA polymerase and capsid protein, respectively. Rosellinia nec...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2692-8
更新日期：2016-05-01 00:00:00
