Abstract：
:Retrovirus infectivity is the result of a cooperative interaction of three structural genes, gag, pol, and env. Since the L-cell endogenous retrovirus (LCV) lacks the env gene translation product, our aim was to study the biological and molecular basis of its non-infectiousness. Fusion experiments between LCV and homologous or heterologous cells demonstrated that virus production could be obtained only after LCV artificial penetration in murine cells and that the new progeny was still noninfectious. Northern blot analysis and heteroduplex mapping of the genomic RNA revealed a 0.99 kb deletion including the 3' region of the pol reading frame, the whole xenotropic and part of the ecotropic domain of the env gene. The results suggest that the observed deletion is responsible for the absence of the gp 70 and the gp 15 E molecules in the virion and seems therefore to be the molecular basis for the non-infectiousness of this retrovirus.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
De Giuli Morghen C,Custode P,Lavanga E,Negri A,Radaelli F,Radaelli Adoi
10.1007/BF01315566subject
Has Abstractpub_date
1988-01-01 00:00:00pages
99-110issue
1-2eissn
0304-8608issn
1432-8798journal_volume
102pub_type
杂志文章abstract：:NDV variants released from the early passaged BHK21/WI-2 cells persistently infected with NDV carry the structural antigen of a latent virus of BHK21/WI-2 cells as a result of phenotypic mixing between NDV and the latent virus. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317290
更新日期：1978-01-01 00:00:00
abstract：:Drug resistance mutations in the Pol gene of human immunodeficiency virus 1 (HIV-1) are one of the critical factors associated with antiretroviral therapy (ART) failure in HIV-1 patients. The issue of resistance to reverse transcriptase inhibitors (RTIs) in HIV infection has not been adequately addressed in the Indian...
journal_title：Archives of virology
pub_type： 杂志文章
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更新日期：2016-05-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050070013
更新日期：2000-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050170193
更新日期：2001-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1670-2
更新日期：2013-08-01 00:00:00
abstract：:Molecular weights of six major polypeptides of infectious bronchitis virus (IBV) are: 1. 75,000; 2. 50,000; 3. 45,000; 4. 35,000; 5. 28,000 or 24,000, and 6. 22,000 dalton. According to the mobility of protein 5 the polypeptide patterns of IBV serotypes fall into two main categories. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315022
更新日期：1979-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050640
更新日期：1999-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0330-y
更新日期：2004-10-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1414-8
更新日期：2013-03-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-04134-4
更新日期：2019-03-01 00:00:00
abstract：:Codiaeum variegatum (common name, garden croton) is an ornamental plant grown for its bright yellow variegated leaf morphology. Two C. variegatum plants with upward leaf curling and vein swelling symptoms were collected in Faisalabad, Pakistan. Sequencing of clones obtained by PCR amplification with specific primers s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04633-3
更新日期：2020-08-01 00:00:00
abstract：:Strawberry crinkle disease is one of the major diseases that threatens strawberry production. Although the biological properties of the agent, strawberry crinkle virus (SCV), have been thoroughly investigated, its complete genome sequence has never been published. Existing RT-PCR-based detection relies on a partial se...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-3860-4
更新日期：2018-09-01 00:00:00
abstract：:Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. LjV has been associated with [corrected] type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Here, we show for th...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1731-6
更新日期：2014-03-01 00:00:00
abstract：:A polymerase chain reaction (PCR) based assay capable of detecting and differentiating seven strains of equine arteritis virus (EAV) from around the world was developed. The primers for the PCR were chosen from the ORF6 gene encoding the unglycosylated membrane protein (M). Viral RNA from cell culture fluids infected ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322675
更新日期：1995-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04424-5
更新日期：2019-12-01 00:00:00
abstract：:Avian influenza due to highly pathogenic avian influenza (HPAIV) H5N1 virus is not a food-borne illness but a serious panzootic disease with the potential to be pandemic. In this study, broiler chickens were vaccinated with commercial H5N1 or H5N2 inactivated vaccines prior to being challenged with an HPAIV H5N1 (clad...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1242-x
更新日期：2012-05-01 00:00:00
abstract：:A putative novel positive-sense (+) RNA virus was detected in isolate CF16158 of the fungus Fusarium graminearum, the causal agent of Fusarium head blight and crown rot in wheat in China. The full genome of this virus was sequenced and characterized. The complete cDNA sequence is 7,051 nt long and contains four open r...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04486-5
更新日期：2020-02-01 00:00:00
abstract：:The entry of enveloped viruses into host cells requires the fusion of viral and cell membranes. These membrane fusion reactions are mediated by virus-encoded glycoproteins. In the case of avian metapneumovirus (aMPV), the fusion (F) protein alone can mediate virus entry and induce syncytium formation in vitro. To inve...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2524-x
更新日期：2015-10-01 00:00:00
abstract：:Transmission electron microscopy was used to confirm the presence of picorna-like virus particles presumed to be Homalodisca coagulata virus-1 (HoCV-1) in the midgut region of adult glassy-winged sharpshooters (GWSS). In addition, we offer a reverse transcription polymerase chain reaction (RT-PCR) assay for the detect...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1066-2
更新日期：2008-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01348028
更新日期：1979-01-01 00:00:00
abstract：:Murine flank scarification with HSV-1 and -2 results in primary lesions at the site of inoculation within three days and lesions at secondary sites within four days. The severity of the infection can be given a numerical value or "score" which is derived from the number and size of these lesions. Using this model, we ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050030
更新日期：2000-01-01 00:00:00
abstract：:A filamentous virus, with particles 600-650 nm long, was purified from Narcissus pseudonarcissus (daffodil) in Hangzhou and an antiserum prepared. After mechanical inoculation, the virus could be detected serologically in Narcissus species but not in some commonly used virus indicators. Infection was symptomless. The ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0801-4
更新日期：2006-11-01 00:00:00
abstract：:A xenotropic Moloney murine leukemia virus-derived recombinant retrovirus (MMuLVSVnlslacZ) has been utilized to study the mechanism of virus entry into endothelial and epithelial porcine cells. In the genome of this recombinant retrovirus, the nlslacZ reporter gene is under the transcriptional control of both LTR and ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314625
更新日期：1992-01-01 00:00:00
abstract：:Little is known about the bacteriophage proteins expressed immediately after infection of the host cell. Most of these early proteins are probably involved in bacteriophage-host interactions redirecting the bacterial metabolism to phage production. Interaction analysis of the first 16 phiKMV gene products (gp) identif...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0967-4
更新日期：2007-01-01 00:00:00
abstract：:Zika virus (ZIKV) is an emerging mosquito-borne flavivirus circulating in Asia and Africa. In 2013, a large outbreak was reported on the archipelago of French Polynesia. In this study, we report the detection and molecular characterization of Zika virus for the first time in Chile from an outbreak among the inhabitant...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2695-5
更新日期：2016-03-01 00:00:00
abstract：:Norovirus (NoV) infection is the most common cause of nonbacterial acute gastroenteritis, which affects both adults and children. However, the molecular epidemiology of NoV in adults with acute gastroenteritis in China has not been investigated extensively. In this study, we investigated the occurrence of NoV infectio...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2440-0
更新日期：2015-07-01 00:00:00
abstract：:The objectives of this study were to determine the antigenic relationship among ruminant adenoviruses and determine their phylogenetic relationship based on the deduced hexon gene amino acid sequence. Results of reciprocal cross-neutralization tests demonstrated antigenic relationships in either one or both directions...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0063-4
更新日期：2008-01-01 00:00:00
abstract：:Mouse cell lines (L, NIH3T3, and RMA cells) infected with the Edmonston strain of measles virus (MV) did not exhibit cytopathic effects (CPE), consistent with the finding that mice are not susceptible to MV. Northern blot analysis, however, revealed that MV genes were transcribed in infected L and NIH3T3 cells, althou...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310037
更新日期：1994-01-01 00:00:00
abstract：:When 66 cucurbit samples with yellowing symptoms from fields in Mali, the Philippines, Thailand and Uzbekistan were screened by RT-PCR using universal polerovirus primers, 21 were identified as harboring polerovirus RNA. When these 21 samples were screened with specific primers for the known cucurbit-infecting polerov...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1939-5
更新日期：2014-06-01 00:00:00
abstract：:Nanoviruses are multi-component plant-infecting single-stranded DNA viruses. Using a viral metagenomics-informed approach, a new nanovirus and two associated alphasatellite molecules have been identified in an uncultivated asymptomatic Vicia cracca plant in the Rhône region of France. This novel nanovirus genome inclu...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3634-4
更新日期：2018-03-01 00:00:00
