Novel positive-sense single-stranded RNA virus related to alphavirus-like viruses from Fusarium graminearum.

Abstract:

:A putative novel positive-sense (+) RNA virus was detected in isolate CF16158 of the fungus Fusarium graminearum, the causal agent of Fusarium head blight and crown rot in wheat in China. The full genome of this virus was sequenced and characterized. The complete cDNA sequence is 7,051 nt long and contains four open reading frames (ORFs). ORF2 is predicted to encode helicase (Hel) and RNA-dependent RNA polymerase (RdRp) domains that are conserved among the alphavirus-like viruses. Pairwise comparisons and phylogenetic analysis of the deduced amino acid sequences of Hel and RdRp indicated that this (+) RNA mycovirus is a novel member of a new, yet to be established family of alphavirus-like viruses. Therefore, we named this virus "Fusarium graminearum alphavirus-like virus 1" (FgALV1). This is the first report of a full-length genomic sequence of a putative alphavirus-like virus in F. graminearum.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Zhang X,Zhang H,Ma D,Chen H,Li W

doi

10.1007/s00705-019-04486-5

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

487-490

issue

2

eissn

0304-8608

issn

1432-8798

pii

10.1007/s00705-019-04486-5

journal_volume

165

pub_type

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