Abstract：
:Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. LjV has been associated with [corrected] type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Here, we show for the first time that Ljungan virus is prevalent (20-27 % positive by PCR) in four species of UK rodent (Myodes glareolus [bank vole], Apodemus sylvaticus [wood mouse], Microtus agrestis [field vole] and Mus musculus [house mouse]). Sequence analysis showed that Ljungan virus of genotypes 1 and 2 were present, although genotype 1 was more prevalent and more frequently associated with brain tissue. This study highlights the prevalence of Ljungan virus in the UK and the need for assessment [corrected] of its zoonotic potential.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Salisbury AM,Begon M,Dove W,Niklasson B,Stewart JPdoi
10.1007/s00705-013-1731-6subject
Has Abstractpub_date
2014-03-01 00:00:00pages
547-51issue
3eissn
0304-8608issn
1432-8798journal_volume
159pub_type
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