Abstract：
:Six synthetic peptides corresponding to regions of bovine enterovirus (BEV), strain VG-5-27, elicited antibodies in mice which reacted with the virus in various assays. These antibodies have been characterised on the basis of their ability to (1) neutralize the virus, (2) bind to the intact virus particle in an immunoprecipitation test, (3) react with the denatured viral proteins, and (4) give immunofluorescent staining of virus infected cells. We have also determined the proportion of antipeptide antibody which binds to the virus in each case. All of the sera immunoprecipitated the virus and neutralized its activity to varying extents. Two of the sera specific for VP 1 sequences failed to react with denatured VP 1 whereas all the other antisera reacted with their respective parental proteins. All of the sera reacted with VG-5-27 infected cells in an immunofluorescence test. The proportion of antibodies to each peptide recognizing intact virus was variable and did not appear to correlate with neutralizing activity. In addition, the ability of each of the sera to react with and neutralize three other strains of the virus was analysed. With one of these strains significant cross-neutralization was observed.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Smyth MS,Trudgett A,Hoey EM,Martin SJ,Brown Fdoi
10.1007/BF01309681keywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
21-33issue
1-4eissn
0304-8608issn
1432-8798journal_volume
126pub_type
杂志文章abstract：:In each infected patient, the population of hepatitis C virus is composed of quasispecies that differ in their nucleotide sequences. Among regions in hepatitis C virus genomes, nucleotide sequences of the hypervariable region have been shown to change quickly during the course of infection. It is not known, however, w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315417
更新日期：1995-01-01 00:00:00
abstract：:We investigated the frequency and the clinical relevance of hepatitis B virus (HBV) pre-S mutations in Qidong, China. The results showed HBV pre-S mutants were detected in 48.4% (47/97) of patients with HBV infection. Both pre-S deletion and pre-S2 start codon mutations were more frequently found in HCC than in CH pat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0176-9
更新日期：2008-01-01 00:00:00
abstract：:Vanilla necrosis potyvirus (VNV) is the cause of significant losses to the South Pacific islands vanilla crop. The gene for the coat protein of VNV has been cloned and sequenced. Comparison of this gene with other potyviral coat protein sequences revealed 97% nucleotide sequence homology (98% amino acid homology) to a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316887
更新日期：1993-01-01 00:00:00
abstract：:Coxsackievirus B3 (CV-B3) has frequently been associated with aseptic meningitis outbreaks in China. To identify sequence motifs related to aseptic meningitis and to construct an infectious clone, the genome sequence of 08TC170, a representative strain isolated from cerebrospinal fluid (CSF) samples from an outbreak i...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2893-9
更新日期：2016-08-01 00:00:00
abstract：:Synthetic peptides comprising the predicted principal neutralizing determinant (PND) in new African and North American HIV-1 clones were tested in ELISA for reactivity with ninety six serum samples from asymptomatic donors in six selected localities in Uganda. Irrespective of the geographical origin of the samples, th...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322666
更新日期：1995-01-01 00:00:00
abstract：:The VP1 encoded by genomic segment B of birnaviruses is generally known to exist as a genome-linked protein (VPg) and as a "free" polypeptide of 90 kDa in virus particles. The guanylylation activity associated with infectious bursal disease virus (IBDV) was demonstrated by incubating purified virus in presence of [alp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050154
更新日期：1997-01-01 00:00:00
abstract：:Atazanavir (ATZ) is a well-tolerated protease inhibitor that can be boosted with ritonavir (r) to treat infection with resistant strains of human immunodeficiency virus 1 (HIV-1). The aim of this meta-analysis was to compare the efficacy, safety, and metabolic effects of ATZ/r regimen versus commonly used antiretrovir...
journal_title：Archives of virology
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00705-017-3346-9
更新日期：2017-08-01 00:00:00
abstract：:A distinct strain of hollyhock yellow vein mosaic virus (HoYVMV) and Ludwigia leaf distortion betasatellite (LuLDB) were associated with yellow vein mosaic of hollyhock. The viral DNA genome (JQ911766) and betasatellite (JQ408216) shared highest nucleotide sequence identity (89.2 %) with HoYVMV (the only available seq...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2108-1
更新日期：2014-10-01 00:00:00
abstract：:A reverse transcription-polymerase chain reaction (RT-PCR) procedure for the detection of avian, duck, and goose reovirus (ARV, DRV, and GRV) RNA from cell culture supernatant and clinical samples was established. Based on multiple sequence alignment, a pair of degenerate primers was selected and synthesized. The ampl...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0731-1
更新日期：2006-08-01 00:00:00
abstract：:Amino acids Lys34, His36, and Phe37 were substituted by PCR-mediated, site-directed mutagenesis for three Trp's in the AcNPV polyhedrin sequence. Phase contrast microscopy revealed refringent, amorphous polyhedra in the nuclei of infected cells. Electron microscopy confirmed a great variation in form and size of the m...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050675
更新日期：2000-01-01 00:00:00
abstract：:Drosophila C virus RNA acted as mRNA in rabbit reticulocyte lysates and directed the synthesis of at least one capsid protein and a number of higher molecular weight proteins. Kinetic analysis by pulse-chase experiments showed that a number of high molecular weight products acted as precursors to the capsid protein(s)...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311694
更新日期：1983-01-01 00:00:00
abstract：:Adenovirus type 7 vaccine strain was engineered to express foreign antigens from both the E3 early promoter in the E3 region and the major late promoter inserted between the E4 region and the right inverted terminal repeat. This multiple expression vector was used to express hepatitis B core antigen (HBcAg), hepatitis...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311300
更新日期：1991-01-01 00:00:00
abstract：:Using gag protein of feline immunodeficiency virus (FIV) expressed in Escherichia coli, an enzyme-linked immunosorbent assay (ELISA) system was developed for detection of antibodies to FIV gag protein in cat sera. With serum samples from cats experimentally infected with several strains and an infectious molecular clo...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309815
更新日期：1992-01-01 00:00:00
abstract：:Poliovirus induces bcl-2-independent apoptosis in the human U937 promonocytic cell line [28]. Here we describe that this cell death, induced after viral infection, correlates with the modulation of the protooncoprotein Bcl-xl. Furthermore, poliovirus infection decreases the detected Bcl-xl in a U937 clone that overexp...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0881-8
更新日期：2002-12-01 00:00:00
abstract：:The objective of this study was to test the ability of bovine viral diarrhea virus (BVDV) to infect mice. Two mice each were either mock infected or inoculated with one of three BVDV strains by the intraperitoneal (IP) (n = 8) or intranasal (IN) (n = 8) route. All mice were euthanized at day 7 postinfection (p.i.). No...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2412-4
更新日期：2015-06-01 00:00:00
abstract：:The E1 nucleic acid sequence of rubella virus strain Judith (RJ) has been cloned into an E. coli expression vector LB03. The reactivity of the expressed unglycosylated antigen (E1J) was compared with its glycosylated counterpart in native virus (RJ) using rabbit and human sera. Rabbit antisera raised against RJ and E1...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317201
更新日期：1992-01-01 00:00:00
abstract：:The chemical nature of the binding sites for vesicular stomatitis virus (VSV) was studied by measuring the ability of solubilized rat brain cell membranes (SRBM) to compete with cultured cells for viral binding. SRBM significantly reduced both binding and infectivity of VSV. After separation of protein and lipid compo...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311075
更新日期：1988-01-01 00:00:00
abstract：:Internal papillomatosis of parrots (IPP) is a tumour disease with unknown etiology, characterised by progressive development of papillomas in the oral and cloacal mucosa. Based on epidemiologic data, infectious agents, particularly DNA tumour viruses, are considered to be involved. In this study, cloacal papillomas we...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0858-7
更新日期：2002-10-01 00:00:00
abstract：:Dengue and chikungunya viruses co-circulate and cause infections that start with similar symptoms but progress to radically different outcomes. Therefore, an early diagnostic test that can differentiate between the two is needed. A single-step multiplex real-time RT-PCR assay was developed that can simultaneously dete...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2217-x
更新日期：2015-01-01 00:00:00
abstract：:Yellow mosaic disease was observed on Jatropha gossypifolia plants growing in Kathaupahadi, Madhya Pradesh, India, and whiteflies (Bemisia tabaci) were found in the vicinity. Association of a new begomovirus with yellow mosaic disease of J. gossypifolia has been detected by PCR using begomovirus DNA-A-specific primers...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1118-5
更新日期：2011-12-01 00:00:00
abstract：:A recombinant encephalomyocarditis virus (rEMCV2887A-egfp) expressing the enhanced green fluorescent protein (EGFP) was produced. The EGFP gene was inserted in frame within the leader protein coding sequence of a full-length cDNA clone of EMCV. RNA transcripts derived from the recombinant full-length cDNA were synthes...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0746-7
更新日期：2006-09-01 00:00:00
abstract：:The ability of human fibroblast interferon to suppress colony formation and papovavirus T-antigen expression in six human tumor cell lines did not appear to correlate with their content of chromosomes 16 and 21. Additional factors or chromosomes may be involved in the manifestation of interferon action in aneuploid ce...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317505
更新日期：1979-01-01 00:00:00
abstract：:In addition to acute infection and disease, foot-and-mouth disease virus (FMDV) can cause persistent infection in ruminants. Such "carrier" animals represent a potential risk for FMDV transmission to susceptible animals. However, the mechanisms and the factors that determine FMDV persistence remain unknown. We describ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2526-8
更新日期：2015-10-01 00:00:00
abstract：:Long terminal repeats (LTRs) of human endogenous retroviruses (HERVs) have been reported to serve as alternative promoters in functional genes. The GSDML (gasdermin-like protein) gene located on human chromosome 17q21 has been found to be an oncogenomic recombination hotspot. Here, we identified the LTR element of HER...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0764-5
更新日期：2006-10-01 00:00:00
abstract：:Here, we present the complete genomic sequence of duck enteritis virus (DEV) strain SD, isolated in China in 2012. The virus was virulent in experimentally infected 2-month-old ducks. The DEV SD genome is 160,945 base pairs (bp) in length. The viral genome sequence, when compared to that of strain DEV CSC, which was i...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04594-7
更新日期：2020-07-01 00:00:00
abstract：:The numbers of the carbohydrate side chains have been analyzed on a series of subtype 7 hemagglutinins of influenza A virus. The procedure employed involves growth of the virus in the presence of the trimming inhibitor N-methyl-1-desoxynojirimycin followed by controlled removal of the resulting mannose-rich oligosacch...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314433
更新日期：1987-01-01 00:00:00
abstract：:Chikungunya fever is self-limiting. However, neurological and hemorrhagic complications have been seen in recent outbreaks. The clinical manifestations of this disease are similar to those of dengue virus infection, indicating the need for differential diagnosis in areas such as India, which are endemic for both virus...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-2829-4
更新日期：2016-06-01 00:00:00
abstract：:One host polypeptide (40,000 daltons) synthesized prior to infection is associated with the 250S RNA polymerase structure partially purified by a combination of velocity sedimentation and isopycnic separation. A series of pulse-chase experiments have shown that a 56,000 dalton polypeptide made during the eclipse phase...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317808
更新日期：1975-01-01 00:00:00
abstract：:Brugmansia suaveolens mottle virus (BsMoV) was the first potyvirus isolated from "angel trumpet" (Brugmansia suaveolens), described in Brazil. In this study, the complete nucleotide (nt) genome sequence of BsMoV was determined, and the deduced amino acid (aa) sequence was analyzed. The BsMoV RNA genome consists of 987...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0798-6
更新日期：2010-10-01 00:00:00
abstract：:Virazole (1, beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide = Ribavirin), a synthetic nucleoside analogue, has been successfully used against tomato spotted wilt virus (TSWV) in tomato and tobacco plants. In tomato, the most efficient concentration to control TSWW was 500 mg/l while in tobacco, concentrations of 10...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315037
更新日期：1980-01-01 00:00:00
