Complete nucleotide sequence and phylogeny of an American strain of yellow fever virus, TRINID79A.

Abstract:

:Yellow fever was presumably imported to the Americas from West-Africa from the 16th to the 19th century. American and African genotypes of the virus are distinguishable, indicating separate evolution in different vector/host cycles. The complete nucleotide sequence of the yellow fever virus strain TRINID79A, isolated in Trinidad in 1979, has been established. It exhibits extensive homology with those of current West-African strains and attenuated strain FNV. However, a unique deletion of the 3' non-coding region (NCR) of the viral RNA has been identified. It indicates that RYF1 and RYF2 repeated sequences of the 3' NCR are not necessary to the replication of the virus.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Pisano MR,Mercier V,Deubel V,Tolou H

doi

10.1007/s007050050708

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

1837-43

issue

9

eissn

0304-8608

issn

1432-8798

pii

91441837.705

journal_volume

144

pub_type

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