Abstract:
:Structural analysis of the US-segment of a viable temperature sensitive human cytomegalovirus mutant (ts9) by the use of restriction enzymes, specific amplifications by the polymerase chain reaction and DNA sequencing, revealed deletions of open reading frames (orf) US14 and part of US15 in addition to that concerning US1 through US13 as reported previously [9]. It was further verified that the Hind III H-fragment and a major portion of the Hind III W-fragment were duplicated in inverted orientation. By the use of a monospecific antibody prepared against a procaryotic recombinant US11-specific product it was shown that the ts9 mutant was in fact deficient in a 30 kDa polypeptide, the gene product of orf US11.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Mockenhaupt T,Reschke M,Bogner E,Reis B,Radsak Kdoi
10.1007/BF01311183subject
Has Abstractpub_date
1994-01-01 00:00:00pages
161-9issue
1-2eissn
0304-8608issn
1432-8798journal_volume
137pub_type
杂志文章abstract::Astroviruses are associated with acute gastroenteritis of human and many animal species. Recently, two studies have reported that novel astroviruses were found in bats. In order to extensively understand the genetic and phylogenetic characterization of bat astroviruses, we tested fecal samples of nine bat species that...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1011-2
更新日期:2011-08-01 00:00:00
abstract::The 87,000-dalton glycoprotein (gp87) of bovine herpesvirus type 1 (BHV-1) was found to selectively attach to susceptible cells. The attachment of gp87 to the cells was markedly decreased by the prior adsorption of intact virions. Anti-gp87 (site Ia) monoclonal antibody, which inhibited BHV-1 adsorption to the cells a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314428
更新日期:1987-01-01 00:00:00
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journal_title:Archives of virology
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doi:10.1007/s00705-017-3548-1
更新日期:2017-12-01 00:00:00
abstract::Sapoviruses (SaVs) belong to the family Caliciviridae and are related to gastroenteritis viruses of humans and animals. These agents have been reported from several countries of the world and represent an important cause of economic loss. The Amazon area has a high degree of diversity of animals and plants, is located...
journal_title:Archives of virology
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doi:10.1007/s00705-013-1904-3
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abstract::Three sets of primers to detect foot-and-mouth disease virus (FMDV) using multiplex RT-PCR were designed based on several reference nucleotide sequences, and their reaction conditions were determined. By testing ten-fold serial dilutions of FMDV, the sensitivity of multiplex RT-PCR is 100 times higher than conventiona...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-1082-y
更新日期:2008-01-01 00:00:00
abstract::Oxidative stress is the process by which reactive molecules and free radicals are formed in cells. In this study, we report the blood-based gene expression profile of oxidative stress and antioxidant genes for identifying surrogate markers of liver tissue in chronic hepatitis C (CHC) patients by using real-time PCR. A...
journal_title:Archives of virology
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doi:10.1007/s00705-020-04564-z
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journal_title:Archives of virology
pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
abstract::The genomes of all replication-competent retroviruses contain cis-acting elements that regulate gene expression. However, the identities of many of these elements remain to be characterized. Inserting sequences into the 3' untranslated region of a replication-competent spleen necrosis virus (SNV) vector disrupted its ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050486
更新日期:1999-01-01 00:00:00
abstract::Outbreaks of swine influenza were first observed in Japan in 1978. A number of influenza viruses were isolated from diseased swine. Almost all viruses isolated were swine influenza virus (Hsw 1 N1) but two viruses isolated from the nasal swabs of swine showing clinical signs of influenza in the Kanagawa prefecture wer...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314741
更新日期:1980-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/BF01347975
更新日期:1975-01-01 00:00:00
abstract::Strains of an influenza H10N4 virus have been isolated during an outbreak of a respiratory disease in mink on the south-east coast of Sweden. This was the first example of a disease in mammals caused by the H10 subtype. We compared the A/mink/Sweden/84 strain with two recent avian H10N4 isolates, one from fowl and ano...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01318353
更新日期:1990-01-01 00:00:00
abstract::In situ hybridization (ISH) and immunohistochemistry (IHC) are essential tools to characterize SARS-CoV-2 infection and tropism in naturally and experimentally infected animals and also for diagnostic purposes. Here, we describe three RNAscope®-based ISH assays targeting the ORF1ab, spike, and nucleocapsid genes and I...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04737-w
更新日期:2020-10-01 00:00:00
abstract::A novel strain of Japanese yam mosaic virus (JYMV-CN) was identified in a yam plant with foliar mottle symptoms in China. The complete genomic sequence of JYMV-CN was determined. Its genomic sequence of 9701 nucleotides encodes a polyprotein of 3247 amino acids. Its organization is virtually identical to that of two J...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2231-z
更新日期:2015-02-01 00:00:00
abstract::A cross-sectional study was undertaken during 2012-2013 to determine the prevalence, strains and factors associated with rotavirus infection among under-5-year-old children hospitalized with acute diarrhea in Uganda. Rotaviruses were detected in 37 % (263/712) of the children. The most prevalent strains were G9P[8] (2...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2742-2
更新日期:2016-04-01 00:00:00
abstract::The disease caused by Newcastle disease virus (NDV) is a severe threat to the poultry industry worldwide. Recently, NDV has been isolated in the Antarctic region. Detailed studies on the mode of evolution of NDV strains isolated worldwide are relevant for our understanding of the evolutionary history of NDV. For this ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2434-y
更新日期:2015-08-01 00:00:00
abstract::Retroviral gag proteins, as well as fragments minimally containing the capsid (CA) and nucleocapsid (NC) subunits of Gag, are able to spontaneously assemble into virus-like particles (VLPs). This occurs in mammalian and bacterial cells as well as in in vitro systems. In every circumstance, nucleic acids are incorporat...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1873-6
更新日期:2014-04-01 00:00:00
abstract::The polypeptides associated with fowlpox virus (FPV) infection of chicken embryo skin (CES) cells were examined by metabolic labelling with [35S]-methionine and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Polypeptide synthesis was followed over the first 48 hours post infection, as this was s...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01320959
更新日期:1987-01-01 00:00:00
abstract::Antibody-like molecules consisting of the human CD 4 extracellular domain fused to human IgG1 heavy chain constant regions were genetically constructed and expressed in a BHK cell stable transfectant. Purified chimeric antibodies bound to HIV particles as it was shown by immuno electron microscopy, inhibited fusions o...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310503
更新日期:1990-01-01 00:00:00
abstract::Classical swine fever (CSF), caused by the CSF virus (CSFV), is a highly contagious disease in pigs. In Korea, vaccination using a live-attenuated strain (LOM strain) has been used to control the disease. However, parenteral vaccination using a live-attenuated strain still faces a number of problems related to storage...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2182-4
更新日期:2014-12-01 00:00:00
abstract::Here, we infected mice with cytopathic bovine viral diarrhea virus 1 (cp BVDV1) by oral inoculation and investigated the effects of infection by histopathological, immunohistochemical (IHC), hematological methods. Twelve mice were infected, and samples were obtained at day 2, 5, and 9 postinfection (pi). Most of the i...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2649-y
更新日期:2016-02-01 00:00:00
abstract::Current subgenotype 2.1 isolates of classical swine fever virus (CSFV) play a dominant role in CSF outbreaks in China, and a novel sub-subgenotype 2.1g of CSFV was recently identified, but the complete genome sequence of this new sub-subgenotype has not been reported. In this study, complete genome of 2.1g isolate GD1...
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pub_type: 杂志文章
doi:10.1007/s00705-016-2932-6
更新日期:2016-09-01 00:00:00
abstract::Morphological, biological, serological, and molecular tests underpin the description of costus stripe mosaic virus (CoSMV) as a new member of the genus Potyvirus, family Potyviridae. Found affecting the native ornamental Costus spiralis in Brazil, the pathogen showed a severely restricted natural and experimental host...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04788-z
更新日期:2020-11-01 00:00:00
abstract::A putative mycovirus belonging to the proposed family "Fusariviridae" was discovered in Setosphaeria turcica by sequencing a double-stranded RNA extracted from this phytopathogenic fungus. The virus was tentatively named "Setosphaeria turcica fusarivirus 1" (StFV1). StFV1 has a genome comprising 6685 nucleotides. The ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-021-04954-x
更新日期:2021-01-06 00:00:00
abstract::The interaction between two different bovine respiratory syncytial virus (BRSV) strains and bovine alveolar macrophages (BAMs) was studied in vitro. Bovine respiratory syncytial virus replicated minimally in BAMs and most of the virus produced remained cell-associated. Approximately 1 out of 1,000 BAMs produced infect...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322681
更新日期:1995-01-01 00:00:00
abstract::We studied the kinetics of localisation of matrix (M) protein of Human respiratory syncytial virus (RSV) in infected cells. M protein was detected in the nucleus early in infection, by confocal microscopy and by immunoblotting of nuclear fractions. We next tested the possibility that M protein may be involved in inhib...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-003-0112-y
更新日期:2003-07-01 00:00:00
abstract::B-cell epitopes of varicella-zoster virus glycoprotein II were mapped by means of solid phase ELISA, synthetic oligopeptides (constructed according to the Davison-Scott sequencing of the varicella-zoster virus genome) and sera from varicellae and herpes zoster patients. The individual pattern of antibody peptide bindi...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01718644
更新日期:1996-01-01 00:00:00
abstract::We determined the complete nucleotide sequence of EDRD-1, a Japanese strain of the North American type-Porcine reproductive and respiratory syndrome virus (PRRSV), and identified a novel 117-base deletion and 108-base insertion previously reported in the nsp2 gene of the SP strain, which contains the largest genome am...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-008-0098-6
更新日期:2008-01-01 00:00:00
abstract::The synthesis of the hemagglutinin (HA) glycoprotein of measles virus was investigated in a persistently infected cell line using a monoclonal anti-HA. The synthesis of the HA protein was shown to be associated with the rough endoplasmic reticulum. The unglycosylated (HA0) apoprotein is synthesized as a 65,000 dalton ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314129
更新日期:1983-01-01 00:00:00
abstract::It is shown that reovirus capsid inner layer consists of 132 capsomeres with a skewed icosahedral pattern of T = 13 (left). 780 structural units composing capsomeres are integrated into trimers. The boundary between capsomeres runs between the structural units forming trimers. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313903
更新日期:1987-01-01 00:00:00
abstract::A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming fro...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-1083-1
更新日期:2008-01-01 00:00:00