Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China.

Abstract:

:A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming from H5N1, H9N2 and other lineages from poultry in Asia. Amino acid motifs within the haemagglutinin sequence of A/Swine/Shandong/nb/2003 suggested it may be able to infect people, whereas the sequences of the other three isolates suggested they would not have had that capability. Our analysis emphasizes the need for a comprehensive study of the interactions between H5N1 and H9N2 viruses in Asia that includes sequencing and phylogenetic investigation.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Shi WF,Gibbs MJ,Zhang YZ,Zhang Z,Zhao XM,Jin X,Zhu CD,Yang MF,Yang NN,Cui YJ,Ji L

doi

10.1007/s00705-007-1083-1

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

211-7

issue

1

eissn

0304-8608

issn

1432-8798

journal_volume

153

pub_type

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