Abstract:
:The synthesis of the hemagglutinin (HA) glycoprotein of measles virus was investigated in a persistently infected cell line using a monoclonal anti-HA. The synthesis of the HA protein was shown to be associated with the rough endoplasmic reticulum. The unglycosylated (HA0) apoprotein is synthesized as a 65,000 dalton peptide and is inserted into the rough endoplasmic reticulum as a transmembrane protein with approximately 2 to 3000 daltons of the peptide exposed to the cytoplasmic membrane surface. Primary glycosylation of the HA protein was found to occur through the lipid-linked carrier, dolichol-phosphate, as determined by inhibition of glycosylation by tunicamycin. Glycosylation, however, was not a prerequisite for membrane insertion. Endo-beta-N-acetylglucosaminidase H digestion of the fully glycosylated HA protein indicated that both simple and complex oligosaccharides are present on the surface glycoprotein.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Bellini WJ,Silver GD,McFarlin DEdoi
10.1007/BF01314129subject
Has Abstractpub_date
1983-01-01 00:00:00pages
87-101issue
1-2eissn
0304-8608issn
1432-8798journal_volume
75pub_type
杂志文章abstract::Chilo iridescent virus (CIV; the type strain of the genus Iridovirus) replicates productively in larvae of the boll weevil, Anthonomus grandis. This study focuses on characterizing productive infections of a boll weevil cell line, BRL-AG-3A (AG3A), starting with CIV reared in the waxworm, Galleria mellonella. We show ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1417-5
更新日期:2012-11-01 00:00:00
abstract::The pathogenicity of 5 different encephalomyocarditis (EMC) virus isolates was investigated in swine fetuses following injection of each virus in utero. Laparotomies were performed on 3 pregnant sows in early mid-third (39-40 days) of gestation and on 5 sows in the late mid-third (70-72 days) of gestation, and groups ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310517
更新日期:1989-01-01 00:00:00
abstract::Since serological donor-screening tests for HIV were introduced in 1985, the safety of donated blood components has improved dramatically. However, these tests do not completely prevent the risk of transfusion-associated HIV infection related to the use of blood donated during the pre-seroconversion window period. Tes...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-011-1085-x
更新日期:2011-11-01 00:00:00
abstract::Structural analysis of the US-segment of a viable temperature sensitive human cytomegalovirus mutant (ts9) by the use of restriction enzymes, specific amplifications by the polymerase chain reaction and DNA sequencing, revealed deletions of open reading frames (orf) US14 and part of US15 in addition to that concerning...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311183
更新日期:1994-01-01 00:00:00
abstract::Bovine leukemia virus (BLV) causes enzootic bovine leucosis (EBL) and is responsible for substantial economic losses in cattle globally. However, information in Africa on the disease is limited. Here, based on clinical, hematological, pathological and molecular analyses, two clinical cases of EBL were confirmed in a d...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-3205-0
更新日期:2017-04-01 00:00:00
abstract::The genome of a Spanish isolate of Broad bean wilt virus-1 (BBWV-1) was completely sequenced and compared with available sequences of other isolates of the genus Fabavirus (BBWV-1 and BBWV-2). This consisted of two RNAs of 5814 and 3431 nucleotides, respectively, and their organization was similar to that of other mem...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-005-0582-1
更新日期:2005-10-01 00:00:00
abstract::DNA of TT virus (TTV), a novel human circovirus, was tested for in 116 mother-infant pairs who had participated in the adult T-cell leukemia prevention program (APP) in Nagasaki, Japan, and refrained from breast-feeding. By polymerase chain reaction with Okamoto's seminested primers, 36 of the 115 (31%) mothers were p...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050044
更新日期:2000-01-01 00:00:00
abstract::Codiaeum variegatum (common name, garden croton) is an ornamental plant grown for its bright yellow variegated leaf morphology. Two C. variegatum plants with upward leaf curling and vein swelling symptoms were collected in Faisalabad, Pakistan. Sequencing of clones obtained by PCR amplification with specific primers s...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04633-3
更新日期:2020-08-01 00:00:00
abstract::Dengue and chikungunya viruses co-circulate and cause infections that start with similar symptoms but progress to radically different outcomes. Therefore, an early diagnostic test that can differentiate between the two is needed. A single-step multiplex real-time RT-PCR assay was developed that can simultaneously dete...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2217-x
更新日期:2015-01-01 00:00:00
abstract::Persistent infection with human cytomegalovirus (HCMV) can be established in cultures of human ovarian teratocarcinoma (PA1) cells, and maintained for more than 200 days. Infected cultures maintained at 34 degrees C (PA1CMV34) and 37 degrees C (PA1CMV37) entered crisis and subsequently displayed massive cytopathic eff...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316737
更新日期:1986-01-01 00:00:00
abstract::Eighty-six varicella-zoster virus (VZV) strains of clades 1, 3 and 5, isolated from varicella and zoster patients in Germany, were analyzed by sequencing the glycoprotein E gene. Four novel non-synonymous and 10 novel synonymous mutations were detected. Of these, two synonymous (C513T, C885T) and two non-synonymous mu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0864-0
更新日期:2011-03-01 00:00:00
abstract::We have sequenced the genome of a novel picornavirus, rabovirus A (rat-borne virus, RaBoV-A, NC_026314), which was present in the feces of a Norway rat (Rattus norvegicus) from Berlin, Germany. This virus is related to members of the genera Enterovirus and Sapelovirus. RaboV-A contains a type II IRES that is unlike th...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2523-y
更新日期:2015-10-01 00:00:00
abstract::Degenerate primers were used to detect and amplify 3'-terminal genome fragments of potyviruses from medicinal aroid plants growing at 16 sites in China. Virus was detected in 7 samples of which six, all of Pinellia ternata, contained a strain of soybean mosaic virus (SMV) similar to that previously reported from this ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-004-0390-z
更新日期:2005-01-01 00:00:00
abstract::We previously generated an RCMV strain in which the r144 gene, encoding a major histocompatibility complex class I homolog, had been deleted (RCMVdelta r144). To investigate the role of r144 during acute infection of neonatal rats, we infected three days-old neonatal rats with either RCMVdelta r144 or wild type (wt) R...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050200028
更新日期:2002-04-01 00:00:00
abstract::Sera and bronchial washings from normal mice and from mice previously infected with influenza virus were analyzed for their concentration of four immunoglobulin (Ig) classes by the method of single radial immunodiffusion and for their content of specific antibody of these Ig classes by the immunofluorescent method. Ig...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314846
更新日期:1977-01-01 00:00:00
abstract::Three genetic variants of grapevine leafroll-associated virus 3 (GLRaV-3) were identified in vineyards of the Western Cape, South Africa. The GLRaV-3 variants were identified by single-strand conformation polymorphism (SSCP) profiles generated from a region amplified in ORF5. ORF5 sequence data confirmed the three gen...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0793-y
更新日期:2010-12-01 00:00:00
abstract::Serological detection of isolated anti-hepatitis B core antibody (anti-HBc) can occur in various scenarios, but the most clinically relevant situation is occult hepatitis B virus (HBV) infection (OBI). The purpose of this study was to evaluate the prevalence and clinical relevance of isolated anti-HBc and of OBI with ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1810-8
更新日期:2014-02-01 00:00:00
abstract::A full-length cDNA clone of olive latent virus 1 (OLV-1), a member of the genus Necrovirus, family Tombusviridae, was subjected to site-directed mutagenesis, and coat protein gene mutants were constructed. A mutant clone, denoted Delta3297, was obtained by deleting the nucleotide in position 3297, thus inducing a fram...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-006-0767-2
更新日期:2006-10-01 00:00:00
abstract::Here, we describe for the first time the complete genome sequence of a new bipartite begomovirus in Madagascar isolated from the weed Asystasia gangetica (Acanthaceae), for which we propose the tentative name asystasia mosaic Madagascar virus (AMMGV). DNA-A and -B nucleotide sequences of AMMGV were only distantly rela...
journal_title:Archives of virology
pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-002-0927-y
更新日期:2003-03-01 00:00:00
abstract::Sapoviruses (SaVs) belong to the family Caliciviridae and are related to gastroenteritis viruses of humans and animals. These agents have been reported from several countries of the world and represent an important cause of economic loss. The Amazon area has a high degree of diversity of animals and plants, is located...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1904-3
更新日期:2014-05-01 00:00:00
abstract::One hundred sixteen rats (Rattus rattus) captured in Indonesia from 2011 to 2012 were investigated for the prevalence of hepatitis E virus (HEV)-specific antibodies and HEV RNA. Using an ELISA based on HEV genotype 4 with an ad hoc cutoff value of 0.500, 18.1 % of the rats tested positive for anti-HEV IgG. By nested R...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1462-0
更新日期:2013-01-01 00:00:00
abstract::We have sequenced the complete genome of an isolate of Banana streak virus from banana cv. 'Mysore' and show that it is sufficiently different from a previously characterised isolate from cv. 'Obino l'Ewai' to warrant recognition as a distinct species, for which the name Banana streak Mysore virus (BSMysV) is proposed...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-004-0471-z
更新日期:2005-04-01 00:00:00
abstract::Pigeon circovirus (PiCV) is taxonomically classified as a member of the Circovirus genus, family Circoviridae. The virus contains a single stranded DNA genome of approximately 2 kb, with minor length variations among different isolates. The occurrence of PiCV infections in pigeons (Columba livia) has been documented w...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-018-3990-8
更新日期:2018-11-01 00:00:00
abstract::Molecular weights of six major polypeptides of infectious bronchitis virus (IBV) are: 1. 75,000; 2. 50,000; 3. 45,000; 4. 35,000; 5. 28,000 or 24,000, and 6. 22,000 dalton. According to the mobility of protein 5 the polypeptide patterns of IBV serotypes fall into two main categories. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315022
更新日期:1979-01-01 00:00:00
abstract::Unfortunately, the original article was published with incorrect accession number and the correct version is updated here. ...
journal_title:Archives of virology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00705-019-04326-6
更新日期:2019-09-01 00:00:00
abstract::The value of serologic tests for diagnosis of swine influenza virus (SIV) infection has been diminished by the emergence of new subtypes and by antigenic drift within subtype. The intensive use of vaccination also has complicated interpretation of serology results. Serologic assays are needed that can detect infection...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-005-0615-9
更新日期:2006-01-01 00:00:00
abstract::The genome of Japanese iris necrotic ring virus (JINRV) consists of a positive-sense ssRNA of 4014 nucleotides with six major open reading frames (ORFs). A 5'-non-coding region of 31 nucleotides precedes the first initiation codon. Like Carnation mottle virus (CarMV), the 5'-proximal three ORFs encode a 26 kDa protein...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050054
更新日期:2000-01-01 00:00:00
abstract::The complete nucleotide sequence of the ssRNA genome of a Chinese GPV isolate of barley yellow dwarf virus (BYDV) was determined. It comprised 5673 nucleotides, and the deduced genome organization resembled that of members of the genus Polerovirus. It was most closely related to cereal yellow dwarf virus-RPV (77% nt i...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0415-8
更新日期:2009-01-01 00:00:00
abstract::The modes of molecular evolution of the coat protein (CP) and 3' non-coding region (NCR) were investigated in Bean yellow mosaic virus (BYMV) isolates, including a new pathotype from blue passion fruit. In phylogenetic analysis, the new pathotype did not cluster with pathotypes or host groups described previously. Int...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0485-7
更新日期:2009-01-01 00:00:00