Abstract：
:Classic neutralization studies by Fazekas de St. Groth and Webster (8) on mixtures of influenza viruses and mixtures of rabbit antisera are reinterpreted in terms of a percentage contaminant in the stock used for the dilution series. A very small amount of a different virus changes the shape of quantal assay curves considerably, but even a large amount of a different antiserum has negligible effect on the shape and merely shifts the curve along the serum dilution axis. These conclusions are the reverse of the authors, who only considered an absolute amount of another component in all dilution tubes. An artificial mixture of 2.7 percent O8 in O1 foot-and-mouth disease virus strains was tested against anti-O1 serum assaying in suckling mice. The small amount of O8 virus greatly altered the shape of the neutralization curve in the direction expected from the reanalysis of the influenza literature data. Results from artificial mixtures are used to explain what were hitherto anomalously broad neutralization curves for some other foot-and-mouth disease strains given by Booth et al. (1) Many of the virus stocks studied can now be postulated as a natural mixture of related virus strains. In fact, the O1 and O8 stocks used might also be of themselves mixtures. These virus strains also exhibit still a further test complication in that the virus-antibody reaction appeared to shift away from complexes on dilution immediately prior to assay.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Trautman Rdoi
10.1007/BF01317497subject
Has Abstractpub_date
1979-01-01 00:00:00pages
257-64issue
3-4eissn
0304-8608issn
1432-8798journal_volume
60pub_type
杂志文章abstract：:Oncogene-containing retroviruses are generated by recombination events between viral and cellular sequences, a phenomenon called "oncogene capture". The captured cellular genes, referred to as "v-onc" genes, then acquire new oncogenic properties. We report a novel feline leukemia virus (FeLV), designated "FeLV-AKT", t...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3192-1
更新日期：2017-04-01 00:00:00
abstract：:Wild plants of the family Convolvulaceae are hosts for a few New World begomoviruses (genus Begomovirus, family Geminiviridae). In this work, we report the complete genome sequence of a new begomovirus infecting the wild convolvulaceous plant Jacquemontia tamnifolia in Venezuela. The cloned bipartite genome showed the...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3372-7
更新日期：2017-08-01 00:00:00
abstract：:We focused on the role of membrane bound sugar residues in the infection of fibroblasts and monocyte-like cells with human cytomegalovirus (HCMV). Treatment of phorbol 12-myristate 13-acetate (PMA) differentiated monocyte-like cells THP-1 or human fibroblasts MRC-5 with lectins specific for N-acetylneuraminic acid (Ne...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322663
更新日期：1995-01-01 00:00:00
abstract：:To understand the mode of persistent infection of Seoul virus in rodents, we examined the distribution of the virus genome and antibody production in infected rats. When 1-day-old rats were inoculated with the KI-83-262 strain, the S segment of viral genome was detected in sera, clots, lungs and kidneys from 3 to 184 ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718634
更新日期：1996-01-01 00:00:00
abstract：:During the epidemic outbreak in the region of Greifswald in the winter 1974/75, we found influenza virus variants which showed differences in the electrophoretic mobility of HA. Among the 25 isolates 13 were of slower and 12 of higher mobility. HA1 of 6 isolates was studied by determining the number of the carbohydrat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310484
更新日期：1991-01-01 00:00:00
abstract：:This work describes the first molecular characterization of grapevine virus B (GVB) in Portuguese grapevine cultivars. During a routine screening of 44 accessions in the National Collection of Grapevine Varieties (CAN PRT051), 17 were found infected with GVB in DAS-ELISA assays with commercial antibodies. However, onl...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3024-3
更新日期：2016-12-01 00:00:00
abstract：:Replication of herpes simplex virus type 1 (HSV-1) in the adrenal gland of mice was observed 12 h after intravenous inoculation, peaked at 48 h (7 x 10(7) PFU/tissue), and was maintained until death. Virus spread to the bilateral intermediolateral column of the thoracic spinal cord. Infected cells appeared in the fasc...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050170048
更新日期：2001-10-01 00:00:00
abstract：:Virological surveillance is an important element in the Polio Eradication Initiative to provide information rapidly about circulating wild polioviruses. Molecular tools have been developed to identify the serotype of the poliovirus strains and whether they are of vaccine or wild origin (intratypic differentiation) and...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0001-x
更新日期：2008-01-01 00:00:00
abstract：:Despite reports that the PB1-F2 protein contributes to influenza virus pathogenicity in the mouse model, little is known about its significance in avian hosts. In our previous study, the A/Vietnam/1203/04 (H5N1) wild-type virus (wtVN1203) was more lethal to mallard ducks than a reverse genetics (rg)-derived VN1203. In...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0666-4
更新日期：2010-06-01 00:00:00
abstract：:We investigated the in situ localization of the 50 kDa protein encoded by ORF2 of Apple chlorotic leaf spot virus (ACLSV) genome which is thought to be a movement protein. In immunogold electron microscopy of ACLSV-infected Chenopodium quinoa leaves, the 50 kDa protein was localized on plasmodesmata and nearby cytopla...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050660
更新日期：1999-01-01 00:00:00
abstract：:Herpes simplex virus type 1 (HSV-1) infection in mutant mice with severe combined immunodeficiency (SCID mice), i.e., mice in which the differentiation of both T and B lymphocytes is severely impaired, was studied. All control (infected and not treated with antibodies or with immune spleen cells) SCID mice were dead b...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01319810
更新日期：1988-01-01 00:00:00
abstract：:Four H7N3 avian influenza viruses (AIVs) were isolated from domestic ducks in live-poultry markets in Zhejiang Province, Eastern China, in 2011. All viruses were characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1370-3
更新日期：2012-10-01 00:00:00
abstract：:The chemical nature of the binding sites for vesicular stomatitis virus (VSV) was studied by measuring the ability of solubilized rat brain cell membranes (SRBM) to compete with cultured cells for viral binding. SRBM significantly reduced both binding and infectivity of VSV. After separation of protein and lipid compo...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311075
更新日期：1988-01-01 00:00:00
abstract：:Whilst bovine leukemia virus (BLV) causes considerable economic losses to the dairy industry worldwide, information on its molecular epidemiology and economic impact in beef cattle is limited. Here, blood from 880 animals from Zambia's major cattle-rearing provinces was screened for BLV by nested PCR. Positive pools w...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04350-6
更新日期：2019-10-01 00:00:00
abstract：:Subnormal temperatures were found to depress the production of interferon by bovid herpesvirus 2 (BHV-2)-infected bovine testicular cells, bovine peripheral blood leukocytes, and bovine monocytes, as well as by BHV-2 antigen-stimulated immune peripheral blood leukocytes. Interferon titers generated at 30 degrees C wer...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311164
更新日期：1984-01-01 00:00:00
abstract：:A flow cytometric virus binding assay that directly visualizes the binding of infectious bursal disease virus (IBDV) to its target cells was established. The chicken B lymphoblastoid cell line, LSCC-BK3, which is permissive for IBDV infection, bound high levels of the virus. Another B lymphoblastoid cell line, LSCC-11...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050464
更新日期：1998-01-01 00:00:00
abstract：:A total of 34 highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) strains isolated from Vietnam during 2013-2014 were sequenced and analyzed. A partial sequence of ORF1a corresponding to the nonstructural protein 2 (Nsp2) coding region and the full sequence of open reading frame 5 (ORF5) g...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2699-1
更新日期：2016-03-01 00:00:00
abstract：:The small intestine of piglets orally infected with rotavirus was examined by electron microscopy 18, 24, 48 and 60 hours after infection. At 18 and 24 hours after infection columnar epithelial cells covered the villi. Infected epithelial cells tended to be less electron-dense than uninfected cells and were more numer...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317902
更新日期：1979-01-01 00:00:00
abstract：:Simian adenovirus SA7 heated for 30 minutes at 70 degrees C retained part of its ability to induce tumors in newborn hamsters. Tumors were also induced by DNA extracted from the heated virus. However, neither residual replicating, i.e. cytopathogenic, nor transforming and T-antigen-inducing activities could be detecte...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317334
更新日期：1981-01-01 00:00:00
abstract：:Tetracyclines have been used to treat many bacterial infections. The use of these antibiotics for the treatment of viral diseases dates to the 1960s to 1970s. Over the decades, the effect of tetracyclines on the pathogenesis of viral infections has been demonstrated both clinically and experimentally. Tetracyclines ca...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-020-04860-8
更新日期：2021-01-01 00:00:00
abstract：:The complete genome sequence of an isolate of euphorbia ringspot virus (EuRSV) was determined by deep sequencing and rapid amplification of cDNA ends (RACE) RT-PCR. It has an RNA genome of 10,154 nucleotides in size, excluding the poly(A) tail, and encodes a polyprotein of 3265 amino acids. Phylogenetic analysis from ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3087-1
更新日期：2017-01-01 00:00:00
abstract：:The complete nucleotide sequence of the RNA genome of turnip mosaic virus Japanese strain (TuMV-J) has been determined from five overlapping cDNA clones and by direct sequencing of viral RNA. The RNA sequence was 9833 nucleotides in length, excluding a 3' terminal poly(A) tail. An AUG triplet at position 130-132 was a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718209
更新日期：1996-01-01 00:00:00
abstract：:The movement protein (MP) of tobacco mosaic virus (TMV) mediates the transport of viral RNA from infected cells to neighboring uninfected cells via plasmodesmata by interacting with putative host factors. To find such host factors, we screened tobacco proteins using the yeast two-hybrid system. NtMPIP1, a novel subset...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0397-6
更新日期：2009-01-01 00:00:00
abstract：:Intravenous polyoma virus inoculation into pregnant Wistar rats resulted in transplacental infection of the foetus, causing tumours and hydronephroses. Cyclosporin A reduced these effects significantly. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313783
更新日期：1993-01-01 00:00:00
abstract：:While infectious bursal disease virus (IBDV) mainly targets immature B cells and causes T cell infiltration in the bursa of Fabricius (BF) of chickens, the effect of IBDV infection on the properties of T cells and relevant cytokine production in avian gut-associated lymphoid tissues (GALTs) remains unknown. Here, we s...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04735-y
更新日期：2020-10-01 00:00:00
abstract：:It has been suggested that antibody overproduction plays a role in the pathogenesis of feline infectious peritonitis (FIP). However, only a few studies on the B-cell activation mechanism after FIP virus (FIPV) infection have been reported. The present study shows that: (1) the ratio of peripheral blood sIg(+) CD21(-) ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0265-9
更新日期：2009-01-01 00:00:00
abstract：:Astroviruses are associated with acute gastroenteritis of human and many animal species. Recently, two studies have reported that novel astroviruses were found in bats. In order to extensively understand the genetic and phylogenetic characterization of bat astroviruses, we tested fecal samples of nine bat species that...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-011-1011-2
更新日期：2011-08-01 00:00:00
abstract：:An apparently single rotavirus A strain possessing a genotype constellation of G8-P[8]-I2-R2-C2-M2-A2-N2-T2-E2-H2 abruptly emerged, caused diarrhoea in children requiring hospitalisation, and increased to reach 27 % of strains detected during the first half of 2015 in Vietnam. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2682-x
更新日期：2016-02-01 00:00:00
abstract：:Cotton, the major cash crop in Pakistan, suffers 30% losses to cotton leaf curl disease, caused by the geminivirus, cotton leaf curl virus DNA A, plus a satellite component, DNA beta responsible for symptom development with plants failing to produce cotton bolls. We constructed transgenic tobacco expressing sense and ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-003-0179-5
更新日期：2003-12-01 00:00:00
abstract：:Insertion of foreign DNA containing the E. coli gpt marker by homologous recombination in the pigeonpox virus (PPV) thymidine kinase (TK) gene and selection for the presence of this DNA in the viral genome produced unstable recombinants after 3 plaque purifications. We highlight the persistence of duplicated TK DNA se...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01378643
更新日期：1993-01-01 00:00:00
