Abstract：
:Replication of herpes simplex virus type 1 (HSV-1) in the adrenal gland of mice was observed 12 h after intravenous inoculation, peaked at 48 h (7 x 10(7) PFU/tissue), and was maintained until death. Virus spread to the bilateral intermediolateral column of the thoracic spinal cord. Infected cells appeared in the fascicular zone of the adrenal cortex 12 h after infection, and cell death was evident in lesions found in the adrenal cortex. Lesions involved the medulla 48 h after inoculation. In cortical lesions, cell nuclei were fragmented or shrunken with little damage to the cytoplasm. DNA fragmentation appeared 12 h after inoculation and increased mainly in cortical lesions, which were characterized by apoptosis induced by HSV-1 infection. In the adrenal medulla, cells were fused and formed multinucleated giant cells but rarely displayed cell death. Macrophages, which serve as a frontal barrier to viral infection in the adrenal gland, especially the cortex, were fewer in number than those found in the liver or spleen. It is likely that HSV-1 easily infects the adrenal gland, resulting in suppression of local immunity, and that adrenal cell apoptosis serves as a primitive type of immunity to limit viral replication.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Aita K,Irie H,Koyama AH,Fukuda A,Yoshida T,Shiga Jdoi
10.1007/s007050170048keywords:
subject
Has Abstractpub_date
2001-10-01 00:00:00pages
2009-20issue
10eissn
0304-8608issn
1432-8798journal_volume
146pub_type
杂志文章abstract：:The complete genome sequences of two grapevine virus L (GVL) isolates collected from the wine grape cultivar Blanc du Bois (Vitis spp.: 'Florida D 6-148'×'Cardinal') in Texas were determined. The two genome sequences (excluding the polyA tail) were each 7594 nucleotide long and 99.7% identical to each other, but they ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04682-8
更新日期：2020-08-01 00:00:00
abstract：:A novel strain of Japanese yam mosaic virus (JYMV-CN) was identified in a yam plant with foliar mottle symptoms in China. The complete genomic sequence of JYMV-CN was determined. Its genomic sequence of 9701 nucleotides encodes a polyprotein of 3247 amino acids. Its organization is virtually identical to that of two J...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2231-z
更新日期：2015-02-01 00:00:00
abstract：:A hemagglutinating virus (8KS0813) was isolated from a red-necked stint. Hemagglutination inhibition and neutralization tests indicated that 8KS0813 was antigenically related to a prototype strain, APMV-6/duck/Hong Kong/18/199/77, but with an 8- and 16-fold difference, respectively, in their titers. The full genome se...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2162-8
更新日期：2014-11-01 00:00:00
abstract：:Three sets of primers to detect foot-and-mouth disease virus (FMDV) using multiplex RT-PCR were designed based on several reference nucleotide sequences, and their reaction conditions were determined. By testing ten-fold serial dilutions of FMDV, the sensitivity of multiplex RT-PCR is 100 times higher than conventiona...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1082-y
更新日期：2008-01-01 00:00:00
abstract：:The present study confirms that herpesviruses (LF) previously isolated from testes and buffy coat cells of male turkeys with semen abnormalities establish a latent infection in testicular cells. These experiments also present the first evidence that these herpesviruses are harbored latently in cells of spinal ganglia....
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311163
更新日期：1984-01-01 00:00:00
abstract：:Antigenic relationships between the Wa, Hochi, Ito, Hosokawa and Nemoto strains of human rotavirus, the SA-11 strain of simian rotavirus, the Lincoln strain of bovine rotavirus, the OSU strain of porcine rotavirus and the R-2 strain of lapine rotavirus, which were all established in cell culture, were studied by neutr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01341726
更新日期：1982-01-01 00:00:00
abstract：:Complete genome sequences of two new isolates of narcissus late season yellows virus (NLSYV) from Australia were compared with the other NLSYV genome from China and with two complete genomes of isolates designated narcissus yellow stripe virus (NYSV), one from Australia and the other from China. On the basis of sympto...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1969-z
更新日期：2014-06-01 00:00:00
abstract：:Modern adjuvants should induce strong and balanced immune responses, and it is often desirable to induce specific types of immunity. As an example, efficient Th1-immunity-inducing adjuvants are highly in demand. Such adjuvants promote good cell-mediated immunity against subunit vaccines that have low immunogenicity th...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-010-0863-1
更新日期：2011-02-01 00:00:00
abstract：:Two group A rotaviruses (ISU-64 and ISU-65) with subgroup I antigen were isolated from pigs with diarrhea and were shown by two-way neutralization tests to be two new serotypes of porcine rotavirus. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310917
更新日期：1988-01-01 00:00:00
abstract：:The highly conserved encapsidation signal (epsilon) of hepatitis B viral (HBV) pregenomic RNA has been reported as an essential component for encapsidation and protein priming of HBV polymerase. Here, we report that two HBV epsilon RNA-binding host proteins (80 and 43 kDa) and a copurifying protein (100 kDa) were puri...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050200001
更新日期：2002-03-01 00:00:00
abstract：:The nucleotide sequence of the granulin gene of Choristoneura fumiferana granulovirus (CfGV) was determined. The gene encodes a protein of 248 amino acids with a predicted Mr of 29.299 kDa. The granulin genes of Trichoplusia ni, Pieris brassicae and Cryptophlebia leucotreta granuloviruses showed homologies ranging fro...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050181
更新日期：1997-01-01 00:00:00
abstract：:The aim of this study was to develop and evaluate a two-tube multiplex real-time RT-PCR assay for the detection and identification of four viral hemorrhagic fever (VHF) pathogens, severe fever with thrombocytopenia syndrome virus (SFTSV), Hantaan virus (HTNV), Seoul virus (SEOV), and dengue virus (DENV), from human cl...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1677-8
更新日期：2013-09-01 00:00:00
abstract：:The structure of the scrapie agent remains unknown. However, scrapie infectivity tends to co-sediment with an infection specific fraction of the glycoprotein PrP (PrPSc) under conditions which solubilise the normal form of this protein (PrPc); accordingly, PrP has been proposed as a candidate component of the agent. T...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01718399
更新日期：1996-01-01 00:00:00
abstract：:The complete genome of O/Akesu/58 strain of foot-and-mouth disease virus (FMDV) was sequenced. The phylogenetic analysis revealed that it is not closely related to epidemic strains or previous strains compared with reference sequences (the identities of complete VP1 nucleotide sequences range from 77.5 to 84.0%). Its ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-1041-y
更新日期：2007-01-01 00:00:00
abstract：:A porcine teschovirus (PTV) was isolated from a dead piglet from a herd of 200 sows showing reproductive failure in Fuyu, Heilongjiang Province, China. Sequencing of most of the genome of this isolate, designated Fuyu/2009, revealed that is was a PTV-8 isolate, closely related to a previously identified Chinese PTV-8 ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1315-x
更新日期：2012-07-01 00:00:00
abstract：:The effects of human alpha-, beta-, or gamma-interferon (IFN) on the replication and production of human T-lymphotrophic virus type-I (HTLV-I) were investigated in a human T-cell line, MT-2. Virus transmission and production estimated by syncytium formation and HTLV-I-associated reverse transcriptase (RT) activity wer...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310623
更新日期：1990-01-01 00:00:00
abstract：:Chimeric plant viruses are emerging as promising vectors for use in innovative vaccination strategies. In this context, cucumber mosaic virus (CMV) has proven to be a suitable carrier of the hepatitis C virus (HCV)-derived R9 mimotope. In the present work, a new chimeric CMV, expressing on its surface the HCV-derived ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0916-7
更新日期：2007-01-01 00:00:00
abstract：:Glycoprotein D (gD) of bovine herpesvirus 1 (BHV-1), a homolog of herpes simplex virus gD, represents a major component of the viral envelope and is a dominant immunogen. To study the antigenic properties of the different regions of gD, we have expressed the full-length gD encoding gene and overlapping fragments spann...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050450
更新日期：1998-01-01 00:00:00
abstract：:Four distinct double-stranded (ds) RNA bands were extracted from leaves of Raphanus sativus-root cv. Yidianhong [corrected] with yellowing at the leaf edge in China. Purified viral particles of 28-30 nm in diameter contained dsRNA segments with the same number and mobility as these extracted directly from radish leave...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0685-8
更新日期：2006-05-01 00:00:00
abstract：:The genomes of a large number of highly diverse novel circular DNA viruses from a wide range of sources have been characterised in recent years, including circular single-stranded DNA (ssDNA) viruses that share similarities with plant-infecting ssDNA viruses of the family Geminiviridae. Here, we describe six novel cir...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2358-6
更新日期：2015-05-01 00:00:00
abstract：:To identify the protein encoded by the L7 region of bovine adenovirus-3 (BAdV-3), specific antisera were raised by immunizing rabbits with bacterial fusion proteins encoding the N-terminus or C-terminus of the BAdV-3 fiber protein. Immunoprecipitation and Western blot analysis confirmed that the fiber is expressed as ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0323-x
更新日期：2004-09-01 00:00:00
abstract：:It is shown that reovirus capsid inner layer consists of 132 capsomeres with a skewed icosahedral pattern of T = 13 (left). 780 structural units composing capsomeres are integrated into trimers. The boundary between capsomeres runs between the structural units forming trimers. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313903
更新日期：1987-01-01 00:00:00
abstract：:Echovirus 33 (E33) has been infrequently detected and is less frequently associated with clinical diseases when compared with other types of enteroviruses (EVs) in China. An outbreak of E33 was identified in four schools in Hunan Province, China, in June 2013. For laboratory diagnosis, throat swabs and/or serum specim...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2059-6
更新日期：2014-09-01 00:00:00
abstract：:In the aim to study the function of the bovine herpesvirus 1 (BoHV-1) UL28 protein during the replicative cycle, we characterized a UL28 deletion mutant of BoHV-1, BoHV-1 Delta UL28. Productive growth of BoHV-1 Delta UL28 was only observed in a specifically engineered complementing cell line expressing the native UL28...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-002-0962-8
更新日期：2003-04-01 00:00:00
abstract：:TT virus (TTV), the first human circovirus to be discovered, appears to be present in most people; less is known about the prevalence of the related TTV-like mini virus (TLMV). A sensitive nested PCR, specific for TLMV, detected the virus in 48% of 201 sera (Norwegian blood donors) previously found to have a 90% preva...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s705-002-8310-6
更新日期：2002-01-01 00:00:00
abstract：:In the Mt. Kosciusko alpine area of Australia there are three well-separated populations of Cardamine lilacina, an endemic sward-forming perennial brassica, and these are infected with turnip yellow mosaic tymovirus. The genetic variation in these viral populations has been assessed by an RNA hybrid mismatch polymorph...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309845
更新日期：1993-01-01 00:00:00
abstract：:The genus Flavivirus (family Flaviviridae) presently comprises around 70 single-strand positive-sense RNA viruses. These replicate in a range of vertebrate and invertebrate cells and may be mosquito-borne, tick-borne or have no-known-vector. Since transmission mode correlates strongly with phylogeny, the flaviviruses ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-005-0626-6
更新日期：2006-02-01 00:00:00
abstract：:The viral DNAs induced by the unclassified animal virus, chicken anaemia agent (CAA), during replication in MDCC-MSB 1 cells have been investigated. Analyses after S1 nuclease, restriction endonuclease and denaturation treatments indicated that infected cell extracts contained genome-size, single-stranded DNA (M(r) 2....
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309811
更新日期：1992-01-01 00:00:00
abstract：:Retrovirus-like particles were isolated from the urine of a patient with psoriasis. The major internal protein, p27, in these particles was isolated by immunosorbent chromatography and gel filtration on a Sephacryl S-300 column in 6 M guanidine hydrochloride. The protein was purified to homogeneity as judged by SDS-PA...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314231
更新日期：1985-01-01 00:00:00
abstract：:We determined the complete genome sequence of a South Korean (SK) isolate of Brugmansia mosaic virus (BruMV), which has recently been proposed to be a member of a new species in the genus Potyvirus. The genomic RNA of BruMV isolate SK is 9781 nucleotides in length (excluding the 3'-terminal poly (A)) and shares comple...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1693-8
更新日期：2013-09-01 00:00:00
