Abstract:
:The small intestine of piglets orally infected with rotavirus was examined by electron microscopy 18, 24, 48 and 60 hours after infection. At 18 and 24 hours after infection columnar epithelial cells covered the villi. Infected epithelial cells tended to be less electron-dense than uninfected cells and were more numerous at 24 hours after infection. Two types of rotavirus particle were seen, usually within dilated cisternae of the RER: non-enveloped particles measuring 50 to 60 nm and enveloped particles measuring 65 to 75 nm. Non-membrane bound viroplasm containing electron-dense cores was encountered outside the cisternae 18 and 24 hours after infection. Tubular structures measuring 44 to 56 nm were often found in nuclei of infected cells. Single-membraned (44 to 55 nm) and double-membraned tubules (70 to 80 nm) associated with viral manufacture were found in the cytoplasm of infected cells. At 48 and 60 hours after infection a proportion of villous epithelial cells were cuboidal. Virus particles were detected in only a few epithelial cells and nuclear and cytoplasmic tubules were not seen. At all times after infection some infected cells showed a reduction in the number and size of the microvilli comprising the brush border.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Pearson GR,McNulty MSdoi
10.1007/BF01317902subject
Has Abstractpub_date
1979-01-01 00:00:00pages
127-36issue
1-2eissn
0304-8608issn
1432-8798journal_volume
59pub_type
杂志文章abstract::Chilo iridescent virus (CIV) belongs to the family Iridoviridae, which are icosahedral cytoplasmic DNA viruses with large, linear, and circularly permuted genomes. Previous studies on infected-cell-specific polypeptides suggested temporal regulation of CIV gene expression. Recently, we demonstrated three temporal clas...
journal_title:Archives of virology
pub_type: 杂志文章
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journal_title:Archives of virology
pub_type: 杂志文章
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310716
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050344
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310484
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journal_title:Archives of virology
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01322675
更新日期:1995-01-01 00:00:00
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doi:10.1007/s00705-006-0851-7
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journal_title:Archives of virology
pub_type: 杂志文章
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更新日期:1976-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315054
更新日期:1977-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0484-8
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04831-z
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01379107
更新日期:1994-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310061
更新日期:1987-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317556
更新日期:1979-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/BF01311358
更新日期:1989-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050698
更新日期:1999-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-001-0794-y
更新日期:2002-05-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316907
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journal_title:Archives of virology
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更新日期:1996-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
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journal_title:Archives of virology
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doi:10.1007/BF01309772
更新日期:1994-01-01 00:00:00
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journal_title:Archives of virology
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abstract::Chronic hepatitis C virus (HCV) infection often leads to liver cancer. The HCV NS2 protein is a hydrophobic transmembrane protein that associates with several cellular proteins in mammalian cells. In this report, we investigated the function of NS2 protein on HCV replication and translation by using a transient cell-b...
journal_title:Archives of virology
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journal_title:Archives of virology
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doi:10.1007/s00705-012-1562-x
更新日期:2013-04-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-003-0258-7
更新日期:2004-06-01 00:00:00
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journal_title:Archives of virology
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更新日期:2009-01-01 00:00:00