The role of epithelial cell differentiation in the expression of herpes simplex virus type 1 in normal human oral mucosa in culture.


:We have examined by immunofluorescent antibody staining technique the expression of herpes simplex virus type 1 (HSV-1) in organ cultures of the normal human oral mucosa. The expression of HSV-1 antigen was found selectively in the epithelial cell layers in relatively undifferentiated states such as basal layer and lower prickle cell layer in addition to the basement membrane. When the epithelial cells dissociated from the oral mucosa were infected with HSV-1 and association of the HSV-1 expression with the cellular differentiation was examined, the epithelial cells containing laminin in an undifferentiated state were permissive for the expression of HSV-1 antigen whereas terminally differentiated epithelial cells with the cornified envelope did not express HSV-1 antigen. These findings indicate that the expression of HSV-1 antigen is restricted in the mucosal epithelial cells in a differentiated state, although the possibility that the cornified envelope might protect the cells from infection is not excluded.


Arch Virol


Archives of virology


Yura Y,Iga H,Terashima K,Yoshida H,Yanagawa T,Hayashi Y,Sato M




Has Abstract


1987-01-01 00:00:00












  • Biosynthesis of measles virus hemagglutinin in persistently infected cells.

    abstract::The synthesis of the hemagglutinin (HA) glycoprotein of measles virus was investigated in a persistently infected cell line using a monoclonal anti-HA. The synthesis of the HA protein was shown to be associated with the rough endoplasmic reticulum. The unglycosylated (HA0) apoprotein is synthesized as a 65,000 dalton ...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Bellini WJ,Silver GD,McFarlin DE

    更新日期:1983-01-01 00:00:00

  • Identification and characterization of a tombusvirus isolated from Japanese gentian.

    abstract::The DECS (dsRNA isolation, exhaustive amplification, cloning and sequencing) analysis technique for viral diagnosis detected a tombusvirus in Japanese gentian not displaying severe symptoms. We tentatively named this virus "gentian virus A" (GeVA). GeVA systemically but inefficiently infected Japanese gentian without ...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Fujisaki K,Tateda C,Shirakawa A,Iwai M,Abe Y

    更新日期:2018-09-01 00:00:00

  • Stable polypeptides associated with the 250S mengovirus-induced RNA polymerase structure.

    abstract::One host polypeptide (40,000 daltons) synthesized prior to infection is associated with the 250S RNA polymerase structure partially purified by a combination of velocity sedimentation and isopycnic separation. A series of pulse-chase experiments have shown that a 56,000 dalton polypeptide made during the eclipse phase...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Loesch WT Jr,Arlinghaus A

    更新日期:1975-01-01 00:00:00

  • Expression profiling and regulatory network of cucumber microRNAs and their putative target genes in response to cucumber green mottle mosaic virus infection.

    abstract::Cucumber green mottle mosaic virus (CGMMV) is an important pathogen of cucumber (Cucumis sativus). The molecular mechanisms mediating host-pathogen interactions are likely to be strongly influenced by microRNAs (miRNAs), which are known to regulate gene expression during the disease cycle. This study focused on 14 miR...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Liang C,Liu H,Hao J,Li J,Luo L

    更新日期:2019-04-01 00:00:00

  • Construction of an infectious cDNA clone of Ribgrass mosaic virus Shanghai isolate and its modification to express an epitope of Mycobacterium tuberculosis.

    abstract::Infectious cDNA clones of the Shanghai isolate of Ribgrass mosaic virus (RMV) were produced by joining four overlapping cDNA fragments and also in a single step by long template PCR. After inoculation of Nicotiana glutinosa with either RNA transcripts or the cDNA under the control of the CaMV 35S promoter, plants deve...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Zhu HQ,Chen JP,Yu SQ

    更新日期:2006-09-01 00:00:00

  • The isolation and partial characterization of a highly pathogenic herpesvirus from the harbor seal (Phoca vitulina).

    abstract::This report describes the first isolation and partial characterization of a herpesvirus from the harbor seal (Phoca vitulina). The virus was isolated during a disease outbreak in a group of young seals nursed in a seal orphanage in The Netherlands. Almost half of the seals died with symptoms of acute pneumonia and foc...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Osterhaus AD,Yang H,Spijkers HE,Groen J,Teppema JS,van Steenis G

    更新日期:1985-01-01 00:00:00

  • Morphogenesis and structure of caprine respiratory syncytial virus.

    abstract::Cell cultures inoculated with caprine respiratory syncytial virus (RSV) were studied with light, fluorescent, and electron microscopy to determine the morphogenesis and structure of the virus. Small syncytia were seen after 36 hours in culture. After 48 hours in culture, syncytia were large and numerous and pleomorphi...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Lehmkuhl HD,Smith MH,Cutlip RC

    更新日期:1980-01-01 00:00:00

  • Kinetic haemagglutination inhibition technique as a means of detecting antigenic variations among strains of Nigerian flaviviruses.

    abstract::Seven isolates of West Nile virus and an additional isolate tentatively identified at the outset as West Nile virus, were compared by Casals' modified haemagglutination inhibition technique. Two of the isolates were nearly identical; a second set of five isolates cross-reacted among themselves within a wide range and ...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Odelola HA,Fabiyi A

    更新日期:1978-01-01 00:00:00

  • Pathogenicity and vaccine efficacy of a thymidine kinase gene deleted infectious laryngotracheitis virus expressing the green fluorescent protein gene.

    abstract::The deletion of the thymidine kinase (TK) gene of herpesviruses causes a reduction in their virulence. However, the effects of the TK gene in infectious laryngotracheitis virus (ILTV) have not been clearly elucidated. In the present study, we constructed a TK gene-deleted recombinant ILTV expressing the green fluoresc...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Han MG,Kweon CH,Mo IP,Kim SJ

    更新日期:2002-05-01 00:00:00

  • Complete nucleotide sequence of loquat virus A, a member of the family Betaflexiviridae with a novel genome organization.

    abstract::Analysis of a loquat tree with leaf curl symptoms by deep sequencing revealed a novel virus with a single-stranded RNA genome, for which the name "loquat virus A" (LoVA) was proposed. The complete genome sequence comprised 7553 nucleotides (nt) and an additional poly(A) tail at the 3' terminus. Sequence comparisons of...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Liu Q,Yang L,Xuan Z,Wu J,Qiu Y,Zhang S,Wu D,Zhou C,Cao M

    更新日期:2020-01-01 00:00:00

  • Nucleotide sequencing of a part of the 5'-noncoding region of echovirus type 9 and rapid virus detection during the acute phase of aseptic meningitis.

    abstract::A part of the 5'-noncoding region of echovirus type 9 isolates was sequenced, and an attempt was made for rapid virus detection in clinical samples obtained from 22 subjects hospitalized with aseptic meningitis. The sequence identity of 440-bp products amplified from the region by RT-PCR was 87.7% between the standard...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Kim GR,Lee JS,Jung YT,Chung YJ,Rhyu MG

    更新日期:1997-01-01 00:00:00

  • Epidemiological trends and virological traits of hepatitis B virus infection in pregnant women and neonates.

    abstract::In infants, hepatitis B virus (HBV) infections are mainly acquired by mother-to-child transmission (MTCT). Current tests for the presence of HBV markers at birth can neither confirm nor exclude MTCT. The aim of this study was to find an early diagnostic marker of HBV MTCT. From 2011 to 2016, we studied a total of 5999...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Peng TT,Cai QE,Yang M,Chen SP,Chen F,Wang M,Peng L,Wong G,Shen CG,Cheng WB,Liu SY,Peng YB,Peng JH,Chen CM,Yang LQ,Tang YM,Xu ZX,Liu YX

    更新日期:2019-05-01 00:00:00

  • Genetic characterization of a novel recombinant echovirus 30 strain causing a regional epidemic of aseptic meningitis in Hokkaido, Japan, 2017.

    abstract::A regional epidemic of aseptic meningitis caused by echovirus 30 (E30) occurred in Hokkaido, Japan, during the period of August-December 2017. To investigate their phylogenetic relationship to other human enteroviruses, we determined the complete genomic nucleotide sequences of isolates from this outbreak. Phylogeneti...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Miyoshi M,Goto A,Komagome R,Yamaguchi H,Maruo Y,Nakanishi M,Ishida S,Nagano H,Sugisawa T,Okano M

    更新日期:2020-02-01 00:00:00

  • The VP2 variable region of African and German isolates of infectious bursal disease virus: comparison with very virulent, "classical" virulent, and attenuated tissue culture-adapted strains.

    abstract::11 African and two German IBDV strains isolated in the mid '80s from field outbreaks in vaccinated and unvaccinated chicken flocks displayed features of very virulent (vv) IBDV strains. The sequence data of the VP2 variable region and phylogenetic analysis confirm that these strains can be grouped within vv IBDV strai...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Zierenberg K,Nieper H,van den Berg TP,Ezeokoli CD,Voss M,Müller H

    更新日期:2000-01-01 00:00:00

  • Genetically distinct strains of Cassava brown streak virus in the Lake Victoria basin and the Indian Ocean coastal area of East Africa.

    abstract::Six isolates of Cassava brown streak virus (CBSV, genus Ipomovirus; Potyviridae) from the Lake Victoria basin in Uganda and Tanzania were characterized. Virus particles were 650 nm long. The complete coat protein (CP)-encoding sequences (1,101 nucleotides, nt) were 90.7-99.5 and 93.7-99.5% identical at the nt and amin...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Mbanzibwa DR,Tian YP,Tugume AK,Mukasa SB,Tairo F,Kyamanywa S,Kullaya A,Valkonen JP

    更新日期:2009-01-01 00:00:00

  • Two distinct begomoviruses associated with an alphasatellite coinfecting Emilia sonchifolia in Thailand.

    abstract::Emilia sonchifolia is a traditionally used medicinal plant that is widespread in tropical and subtropical regions of the world. Yellow vein symptoms were observed in E. sonchifolia plants in fields in the county of Koh Samui, Surat Thani Province, Thailand, in August 2015. Two distinct begomoviruses, designated TH4872...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Zhao L,Zhong J,Zhang X,Yin Y,Li T,Ding M

    更新日期:2018-06-01 00:00:00

  • Pattern of N gene-mediated systemic hypersensitive response and turnover of viral replicase protein in tobacco.

    abstract::We examined the pattern of the N gene-mediated systemic hypersensitive response (HR), which was induced by tobacco mosaic virus upon temperature shift, and analyzed the distribution of the coat protein and the virus-encoded 126 kDa replicase protein (126 K protein) by immunoblot analysis. In the middle- and lower-posi...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Someya N,Niinuma K,Kimura M,Yamaguchi I,Hamamoto H

    更新日期:2004-11-01 00:00:00

  • Isolation and phylogeny of endogenous retrovirus HERV-F family in Old World monkeys. Brief report.

    abstract::A new human endogenous retroviral family (HERV-F) has recently been identified from human chromosome 7q31.1-q31.3 that was identical to the XA34 cDNA clone isolated from a human glioma cDNA library with an ERV-9 env probe. We investigated pol fragments of the HERV-F family from the Old World monkeys (crab-eating monke...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Kim HS,Hyun BH,Takenaka O

    更新日期:2002-01-01 00:00:00

  • Taxonomic position of sugarcane streak mosaic virus in the family Potyviridae.

    abstract::AcDNA library was generated from purified RNA of sugarcane streak mosaic virus--Andhra Pradesh (SCSMV-AP). Two overlapping clones covering 3160 nucleotides encoding partial CI, complete 6K2, VPg-NIa and NIb genes were sequenced. A comparison of this sequence along with the 3' terminal 1315 nucleotides of SCSMV-AP dete...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Hema M,Sreenivasulu P,Savithri HS

    更新日期:2002-10-01 00:00:00

  • Merkel cell polyomavirus IgG antibody levels are associated with progression to AIDS among HIV-infected individuals.

    abstract::The association of Merkel cell polyomavirus (MCPyV) with Merkel cell carcinoma (MCC) in immunocompromised individuals has been revealed in a number of surveys. The study of MCPyV specific antibody titers and viral loads in such patients has a great attraction for research groups interested in viral reactivation. In th...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Vahabpour R,Nasimi M,Naderi N,Salehi-Vaziri M,Mohajel N,Sadeghi F,Keyvani H,Monavari SH

    更新日期:2017-04-01 00:00:00

  • Evidence of apoptosis induced by viral protein 2 of chicken anaemia virus.

    abstract::Although viral protein 3 (VP3) of chicken anaemia virus (CAV) has been well recognised as an inducer of apoptosis, viral protein 2 (VP2) of the virus has only been speculated to have apoptotic activity. This has not been verified because the open reading frame (ORF) encoding VP2 completely encompasses that encoding VP...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Kaffashi A,Pagel CN,Noormohammadi AH,Browning GF

    更新日期:2015-10-01 00:00:00

  • Detection of a novel border disease virus subgroup in Tunisian sheep.

    abstract::Nine pestiviruses isolated from different batches of a contaminated Tunisian sheep pox vaccine and one Tunisian field ovine isolate of border disease virus (BDV) were studied at the antigenic and molecular levels. Seroneutralization tests were carried out on three vaccine isolates, the Tunisian field isolate and repre...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Thabti F,Letellier C,Hammami S,Pépin M,Ribière M,Mesplède A,Kerkhofs P,Russo P

    更新日期:2005-02-01 00:00:00

  • Structure and variability of the 3' end of RNA 3 of Beet soil-borne pomovirus--a virus with uncertain pathogenic effects.

    abstract::PCR products representing c. 550 3' terminal bases of Beet soil-borne pomovirus (BSBV) RNA 3 were compared for sources of this virus from all major sugarbeet-growing areas in Germany. In none of these areas conspicious symptoms could be attributed to the presence of BSBV. Single strand conformation polymorphism analys...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Koenig R,Pleij CW,Büttner G

    更新日期:2000-01-01 00:00:00

  • Proposal for a unified norovirus nomenclature and genotyping.

    abstract::Noroviruses belong to a genus of genetically diverse viruses within the family Caliciviridae and cause acute gastroenteritis in humans and animals. They are subdivided into genogroups, each of which further segregates into genotypes. Until recently, a new genotype was based on a defined pairwise distance cutoff of com...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Kroneman A,Vega E,Vennema H,Vinjé J,White PA,Hansman G,Green K,Martella V,Katayama K,Koopmans M

    更新日期:2013-10-01 00:00:00

  • Analysis of genetic variation of porcine circovirus type 2 within pig populations in central China.

    abstract::In order to investigate the genetic diversity of porcine circovirus type 2 (PCV2), 284 clinical tissue samples were collected from different pig farms in central China from 2015 to 2017. A total of 162 tissue samples (162/284, 57.04%) were positive for PCV2 by PCR, and subsequently, the complete genome of 36 of these ...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Xu PL,Zhao Y,Zheng HH,Tian RB,Han HY,Chen HY,Zheng LL

    更新日期:2019-05-01 00:00:00

  • Analysis of some phenotypic traits of feces-borne temperate lambdoid bacteriophages from different immunity groups: a high incidence of cor+, FhuA-dependent phages.

    abstract::A group of previously isolated heterogeneous mEp lambdoid phages (43) from 19 different immunity groups for phage infection was further characterized to gain insight into some phenotypic traits and to assess their relationship with phage lambda. Interestingly, the FhuA host receptor was required by the majority of mEp...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Hernández-Sánchez J,Bautista-Santos A,Fernández L,Bermúdez-Cruz RM,Uc-Mass A,Martínez-Peñafiel E,Martínez MA,García-Mena J,Guarneros G,Kameyama L

    更新日期:2008-01-01 00:00:00

  • Computational analysis of the effect of polymerase acidic (PA) gene mutation F35L in the 2009 pandemic influenza A (H1N1) virus on binding aspects of mononucleotides in the endonuclease domain.

    abstract::An F35L mutation in the N-terminal domain of the polymerase acidic protein (PA-Nter), which contains the active site of the endonuclease, has been reported to result in higher polymerase activity in mouse-adapted strains of the 2009 pandemic influenza A H1N1 virus. We modeled wild and mutant complexes of uridine 5'-mo...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Bhoye D,Cherian SS

    更新日期:2018-04-01 00:00:00

  • Avian reovirus σA and σNS proteins activate the phosphatidylinositol 3-kinase-dependent Akt signalling pathway.

    abstract::The present study was conducted to identify avian reovirus (ARV) proteins that can activate the phosphatidylinositol 3-kinase (PI3K)-dependent Akt pathway. Based on ARV protein amino acid sequence analysis, σA, σNS, μA, μB and μNS were identified as putative proteins capable of mediating PI3K/Akt pathway activation. T...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Xie L,Xie Z,Huang L,Fan Q,Luo S,Huang J,Deng X,Xie Z,Zeng T,Zhang Y,Wang S

    更新日期:2016-08-01 00:00:00

  • Some biological and physico-chemical properties of egg drop syndrome (EDS) avian adenovirus strain B8/78.

    abstract::The EDS adenovirus produced either in the allantoic cavity of embryonated duck eggs (A0 virus) or in chicken embryo liver cell cultures (TC0 virus) were comparatively studied by gradient ultracentrifugation in CsCl. The A0 viral particles banded at densities of 1.36 and 1.31 g/ml, whereas, the TC0 viral particle were ...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Zsák L,Kisary J

    更新日期:1981-01-01 00:00:00

  • Anti-idiotypic antibodies against Puumala virus glycoprotein-specific monoclonal antibodies inhibit virus infection in cell cultures.

    abstract::Rabbit anti-idiotypic antibodies (anti-ids) were generated against three bank vole and one human monoclonal antibody (MAb) specific for the two envelope glycoproteins of Puumala virus (G1 and G2). The anti-ids were purified by sequential immunoaffinity chromatography. Each anti-id inhibited the antigen binding of its ...

    journal_title:Archives of virology

    pub_type: 杂志文章


    authors: Lundkvist A,Scholander C,Niklasson B

    更新日期:1993-01-01 00:00:00