Abstract:
:The prevalence of HIV-1 infection in men who have sex with men (MSM) in China has drastically increased, and circulating strains may have acquired transmitted drug resistance (TDR). We determined TDR genotypes among antiretroviral therapy (ART)-naïve MSM in 19 provinces/cities where HIV-1 prevalence among MSM is high, and found an overall 4.9 % TDR rate. Although protease inhibitors (PI) were not in the first-line antiretroviral drug list provided through the National ART Program, 70.4 % of the detected TDR belongs to this category. Our findings confirm the urgent need for TDR surveillance in order to optimize treatment effects of the National ART Program.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Yang J,Xing H,Niu J,Liao L,Ruan Y,He X,Feng Y,Li Z,Shao Ydoi
10.1007/s00705-012-1557-7subject
Has Abstractpub_date
2013-04-01 00:00:00pages
839-44issue
4eissn
0304-8608issn
1432-8798journal_volume
158pub_type
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journal_title:Archives of virology
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更新日期:2016-05-01 00:00:00
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journal_title:Archives of virology
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doi:10.1007/s00705-002-0885-4
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journal_title:Archives of virology
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journal_title:Archives of virology
pub_type: 杂志文章
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journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315679
更新日期:1978-01-01 00:00:00
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journal_title:Archives of virology
pub_type: 杂志文章
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journal_title:Archives of virology
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更新日期:1989-01-01 00:00:00