Transcriptional control of the HERV-H LTR element of the GSDML gene in human tissues and cancer cells.

Abstract:

:Long terminal repeats (LTRs) of human endogenous retroviruses (HERVs) have been reported to serve as alternative promoters in functional genes. The GSDML (gasdermin-like protein) gene located on human chromosome 17q21 has been found to be an oncogenomic recombination hotspot. Here, we identified the LTR element of HERV-H with reverse orientation as an alternative promoter of the GSDML gene and analyzed its expression pattern in human tissues and cancer cells. A reporter gene assay of the promoter activity of the LTR on the GSDML gene in human cancer cell lines (HCT-116 and HeLa) and a kidney cell line (Cos7) of African green monkey indicated that the LTR promoter with reverse orientation had stronger promoter activity than forward one. The transcripts of this LTR-derived promoter were widely distributed in various human tissues and cancer cells, whereas the transcripts of the cellular promoter were found only in stomach tissues and some cancer cells (HCT116, MCF7, U937, C-33A, and PC3). These findings suggest that the LTR element on the GSDML gene was integrated into the hominoid lineage and acquired the role of transcriptional regulation of human tissues and cancer cells.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Sin HS,Huh JW,Kim DS,Kang DW,Min DS,Kim TH,Ha HS,Kim HH,Lee SY,Kim HS

doi

10.1007/s00705-006-0764-5

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

1985-94

issue

10

eissn

0304-8608

issn

1432-8798

journal_volume

151

pub_type

杂志文章
  • Physiochemical and immunological characterization of hepatitis A virus nucleocapsids expressed in a vaccinia virus/T7/EMCV system.

    abstract::Expression of the entire open reading frame of hepatitis A virus was achieved in a vaccinia virus/T7/EMCV hybrid system. The expressed antigens were characterized as particles with buoyant densities and sedimentation coefficients typical of empty capsids and pentamers of HAV. This was further confirmed by electron mic...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01310029

    authors: Zhu NL,Li GD,Wang Y

    更新日期:1994-01-01 00:00:00

  • Exposure to watermelon bud necrosis virus and groundnut bud necrosis virus alters the life history traits of their vector, Thrips palmi (Thysanoptera: Thripidae).

    abstract::Thrips palmi transmits the tospoviruses watermelon bud necrosis (WBNV) and groundnut bud necrosis virus (GBNV) in persistent propagative way. Little is known about the T. palmi-WBNV and -GBNV relationship. In this study, we report the effects of WBNV and GBNV infection on the life history traits of T. palmi. Both WBNV...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04381-z

    authors: Ghosh A,Basavaraj YB,Jangra S,Das A

    更新日期:2019-11-01 00:00:00

  • Immunogenicity of non-structural proteins of foot-and-mouth disease virus: differences between infected and vaccinated swine.

    abstract::Non-structural as well as VP1 recombinant proteins of foot-and-mouth disease virus (FMDV) produced in E. coli, have been used to study the specific antibody response of infected or vaccinated swine. An analysis of sera from infected pigs, using a direct ELISA, showed that polypeptide 3ABC (spanning non-structural prot...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01538822

    authors: Rodríguez A,Dopazo J,Sáiz JC,Sobrino F

    更新日期:1994-01-01 00:00:00

  • The prevalence and genetic diversity of porcine circovirus types 2 and 3 in Northeast China from 2015 to 2018.

    abstract::A total of 472 samples from domestic pigs collected in China from 2015 to 2018 were tested for the presence of porcine circovirus types 2 and 3 (PCV2 and PCV3, respectively) by conventional polymerase chain reaction analysis. The prevalence of PCV2, PCV3, and PCV2/3 co-infection was 50.0%, 13.3%, and 6.78%, respective...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04336-4

    authors: Xia D,Huang L,Xie Y,Zhang X,Wei Y,Liu D,Zhu H,Bian H,Feng L,Liu C

    更新日期:2019-10-01 00:00:00

  • Host cell proteins binding to the encapsidation signal epsilon in hepatitis B virus RNA.

    abstract::The highly conserved encapsidation signal (epsilon) of hepatitis B viral (HBV) pregenomic RNA has been reported as an essential component for encapsidation and protein priming of HBV polymerase. Here, we report that two HBV epsilon RNA-binding host proteins (80 and 43 kDa) and a copurifying protein (100 kDa) were puri...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050200001

    authors: Shin HJ,Kim SS,Cho YH,Lee SG,Rho HM

    更新日期:2002-03-01 00:00:00

  • Optimization of a magnetic capture RT-LAMP assay for fast and real-time detection of potato virus Y and differentiation of N and O serotypes.

    abstract::Potato virus Y (PVY) infection has been a global challenge for potato production and the leading cause of downgrading and rejection of seed crops for certification. Accurate and timely diagnosis is a key for effective disease control. Here, we have optimized a reverse transcription loop-mediated amplification (RT-LAMP...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-017-3635-3

    authors: Treder K,Chołuj J,Zacharzewska B,Babujee L,Mielczarek M,Burzyński A,Rakotondrafara AM

    更新日期:2018-02-01 00:00:00

  • Cucumber mosaic virus as carrier of a hepatitis C virus-derived epitope.

    abstract::Cucumber mosaic virus (CMV) is a three component isodiametric plant virus which is common worldwide and has an extremely wide host range. A pseudorecombinant was made, derived from the RNA3 component of the CMV-S strain, carrying the coat protein (CP) gene, and the RNA1,2 components of the CMV-D strain. This system de...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-003-0190-x

    authors: Natilla A,Piazzolla G,Nuzzaci M,Saldarelli P,Tortorella C,Antonaci S,Piazzolla P

    更新日期:2004-01-01 00:00:00

  • Effect of tunicamyein on the morphogenesis of Semliki Forest virus and Rous sarcoma virus.

    abstract::Semliki Forst Virus (SFV) infected chick embroyo cells (CEC) incubated in the presence of Tunicamyein, a drug which specifically inhibits glycosylation, were studied under the electron microscope. No extracellular virions were produced although intracellular viral nucleocapsids in paracrystalline form were detected. U...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01314489

    authors: Ogura H,Schmidt MF,Schwarz RT

    更新日期:1977-01-01 00:00:00

  • Detection of Epstein-Barr virus infection in the epithelial cells and lymphocytes of non-neoplastic tonsils by in situ hybridization and in situ PCR.

    abstract::Non-neoplastic tonsils were analyzed for detection of Epstein-Barr virus (EBV)-positive cells by in situ hybridization and in situ PCR. EBV-encoded small nuclear RNA 1(EBER1)-positive cells were found in 28.2% of the tonsils and were evenly localized in the extrafollicular area and within germinal centers. Latent memb...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050050332

    authors: Kobayashi R,Takeuchi H,Sasaki M,Hasegawa M,Hirai K

    更新日期:1998-01-01 00:00:00

  • Mint virus X: a novel potexvirus associated with symptoms in 'Variegata' mint.

    abstract::Mentha x gracilis 'Variegata', an ornamental mint clone first described about 200 years ago, exhibits virus-like vein banding symptoms. Double-stranded RNA and virion isolations revealed the presence of three viruses in a 'Variegata' plant. Cloning and sequencing disclosed that one of the viruses was a previously unid...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-005-0586-x

    authors: Tzanetakis IE,Postman JD,Martin RR

    更新日期:2006-01-01 00:00:00

  • Antibodies that cross-neutralize the tier-2 pseudoviruses are produced in antiretroviral-naïve HIV-1-infected children from northern India.

    abstract::In this cross-sectional study, we evaluated the efficiency of the plasma of 38 antiretroviral-naïve HIV-1-infected children from northern India against a standard panel of pseudoviruses (3 clade C and 3 clade B) by TZM-bl assay. Neutralization potential was observed to a variable extent, with a potency ranging up to r...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-012-1357-0

    authors: Prakash SS,Andrabi R,Kumar R,Lodha R,Kabra SK,Vajpayee M,Luthra K

    更新日期:2012-09-01 00:00:00

  • Multiple polyadenylated RNA viruses detected in pooled cultivated and wild plant samples.

    abstract::RNA extracted from 120 leaf specimens from 17 plant species was pooled, and polyadenylated RNA species were sequenced together without barcoding in one lane using massively parallel sequencing technology. After analysis, complete or partial genome sequences representing 20 virus isolates of 16 polyadenylated RNA speci...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-011-1166-x

    authors: Wylie SJ,Luo H,Li H,Jones MG

    更新日期:2012-02-01 00:00:00

  • Molecular characterization of two prunus necrotic ringspot virus isolates from Canada.

    abstract::We determined the entire RNA1, 2 and 3 sequences of two prunus necrotic ringspot virus (PNRSV) isolates, Chr3 from cherry and Pch12 from peach, obtained from an orchard in the Niagara Fruit Belt, Canada. The RNA1, 2 and 3 of the two isolates share nucleotide sequence identities of 98.6%, 98.4% and 94.5%, respectively....

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-012-1247-5

    authors: Cui H,Hong N,Wang G,Wang A

    更新日期:2012-05-01 00:00:00

  • Analysis of genetic variation of porcine circovirus type 2 within pig populations in central China.

    abstract::In order to investigate the genetic diversity of porcine circovirus type 2 (PCV2), 284 clinical tissue samples were collected from different pig farms in central China from 2015 to 2017. A total of 162 tissue samples (162/284, 57.04%) were positive for PCV2 by PCR, and subsequently, the complete genome of 36 of these ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04205-0

    authors: Xu PL,Zhao Y,Zheng HH,Tian RB,Han HY,Chen HY,Zheng LL

    更新日期:2019-05-01 00:00:00

  • Development and evaluation of a rapid recombinase polymerase amplification assay for the detection of human enterovirus 71.

    abstract::Enterovirus 71 (EV71) is one of the most common pathogens of hand, foot, and mouth disease (HFMD). A rapid reverse transcription recombinase polymerase amplification (RT-RPA) assay was established to detect EV71 subgenotype C4 (EV71-C4). The 95% detection limit of the RT-RPA was 3.767 log10 genomic copies (LGC)/reacti...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-018-3859-x

    authors: Yin D,Zhu Y,Wang K,Wang J,Zhang X,Han M,He Y,Chen Q,Hu G

    更新日期:2018-09-01 00:00:00

  • Detection of a novel border disease virus subgroup in Tunisian sheep.

    abstract::Nine pestiviruses isolated from different batches of a contaminated Tunisian sheep pox vaccine and one Tunisian field ovine isolate of border disease virus (BDV) were studied at the antigenic and molecular levels. Seroneutralization tests were carried out on three vaccine isolates, the Tunisian field isolate and repre...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-004-0427-3

    authors: Thabti F,Letellier C,Hammami S,Pépin M,Ribière M,Mesplède A,Kerkhofs P,Russo P

    更新日期:2005-02-01 00:00:00

  • Expression profiling and regulatory network of cucumber microRNAs and their putative target genes in response to cucumber green mottle mosaic virus infection.

    abstract::Cucumber green mottle mosaic virus (CGMMV) is an important pathogen of cucumber (Cucumis sativus). The molecular mechanisms mediating host-pathogen interactions are likely to be strongly influenced by microRNAs (miRNAs), which are known to regulate gene expression during the disease cycle. This study focused on 14 miR...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-019-04152-w

    authors: Liang C,Liu H,Hao J,Li J,Luo L

    更新日期:2019-04-01 00:00:00

  • Hepatitis C virus infection in mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma: evidence for a pathogenetic role.

    abstract::We investigated the pathogenetic relevance of hepatitis C virus (HCV) infection in mixed cryoglobulinemia (MC) with or without complicating B-cell Non-Hodgkin's lymphoma (NHL) in comparison with other immunological and lymphoproliferative disorders. The following groups of patients were studied: A) 25 patients with MC...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s007050050100

    authors: Zignego AL,Ferri C,Giannini C,La Civita L,Careccia G,Longombardo G,Bellesi G,Caracciolo F,Thiers V,Gentilini P

    更新日期:1997-01-01 00:00:00

  • Infected cell specific protein and viral DNA synthesis in productive and abortive infections of Spodoptera frugiperda nuclear polyhedrosis virus.

    abstract::This study examines viral protein and DNA synthesis in Spodoptera frugiperda multicapsid nuclear polyhedrosis virus (SfMNPV) infections of S. frugiperda and Trichoplusia ni cells. A total of 28 infected cell specific polypeptides (ICSPs) were detected in the productive S. frugiperda cells. Of these, 14 were identified...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01310626

    authors: Liu HS,Bilimoria SL

    更新日期:1990-01-01 00:00:00

  • Characterisation of novel linear antigen epitopes on North American-type porcine reproductive and respiratory syndrome virus M protein.

    abstract::The M protein, encoded by the porcine reproductive and respiratory syndrome virus (PRRSV) ORF6 gene, is considered to be one of the most conserved PRRSV proteins. In recent decades, highly specific monoclonal antibodies (Mabs) have been exploited to provide reliable diagnoses for many diseases. In this study, two diff...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-014-2174-4

    authors: Wang Q,Chen J,Peng J,An T,Leng C,Sun Y,Guo X,Ge X,Tian Z,Yang H

    更新日期:2014-11-01 00:00:00

  • Evaluation of susceptibility of HIV-1 CRF01_AE variants to neutralization by a panel of broadly neutralizing antibodies.

    abstract::Broadly neutralizing antibodies (bNAbs) are very promising agents for HIV-1 prophylaxis and AIDS treatment. However, the neutralization susceptibility of circulating recombinants such as CRF01_AE, which is becoming increasingly prevalent, has not been studied in detail until now. Here, we focused on CRF01_AE in China ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-018-4011-7

    authors: Wang H,Yuan T,Li T,Li Y,Qian F,Zhu C,Liang S,Hoffmann D,Dittmer U,Sun B,Yang R

    更新日期:2018-12-01 00:00:00

  • Variations in the H/ACA box sequence of viral telomerase RNA of isolates of CVI988 Rispens vaccine.

    abstract::The use of the complete DNA sequence for the Marek's disease virus (MDV) serotype 1 vaccine strain CVI988 Rispens in comparative genomic studies with virulent strains of MDV has revealed the presence of a number of insertions, deletions and single-nucleotide polymorphisms. In this study, we investigated a SNP in the H...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-008-0152-4

    authors: Debba-Pavard M,Le Galludec H,Dambrine G,Rasschaert D

    更新日期:2008-01-01 00:00:00

  • [Local immune response in mouse experimental airborne influenza: immunoglobulin concentrations, antibody levels of immunoglobulin classes and anamnestic response in bronchial washings (author's transl)].

    abstract::Sera and bronchial washings from normal mice and from mice previously infected with influenza virus were analyzed for their concentration of four immunoglobulin (Ig) classes by the method of single radial immunodiffusion and for their content of specific antibody of these Ig classes by the immunofluorescent method. Ig...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01314846

    authors: Lemercier G,Neveu D,Morel J,Fontanges R

    更新日期:1977-01-01 00:00:00

  • Outbreak of influenza virus A/H1N1 in a hospital ward for immunocompromised patients.

    abstract::In February 2008, five patients were infected with the H1N1 subtype of influenza A virus in one hospital ward for immunocompromised patients at a hospital in North Rhine-Westphalia, Germany. All of these patients had an established haematologic disease and tested positive either for viral RNA or antigen shortly after ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-010-0771-4

    authors: Grund S,Roggendorf M,Schweiger B

    更新日期:2010-11-01 00:00:00

  • Spatial distribution of orally administered viral fusolin protein in the insect midgut and possible synergism between fusolin and digestive proteases to disrupt the midgut peritrophic matrix.

    abstract::Oral inoculation of entomopoxvirus spindles, microstructures composed of fusolin protein, causes disruption of the peritrophic matrix (PM), a physical barrier against microbe infection, in the insect midgut. Although the atomic structure of fusolin has been determined, little has been directly elucidated of the mechan...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-018-4013-5

    authors: Mitsuhashi W,Shimura S,Miyamoto K,Sugimoto TN

    更新日期:2019-01-01 00:00:00

  • Restriction maps of the DNA of cervid herpesvirus 1 and cervid herpesvirus 2, two viruses related to bovine herpesvirus 1.

    abstract::Restriction maps of cervid herpesviruses 1 and 2 which are antigenetically related to bovine herpesvirus 1, were deduced from Southern blot hybridization with HindIII restriction fragments of BHV-1 DNA as probes. ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01309448

    authors: Vanderplasschen A,Bublot M,Pastoret PP,Thiry E

    更新日期:1993-01-01 00:00:00

  • Transplacental infection and embryonic death following maternal exposure to porcine parvovirus near the time of conception.

    abstract::Each of 20 gilts (principals) from a commercial swine herd free of antibody for porcine parvovirus (PPV) was exposed intranasally and orally to PPV at the onset of gestation. The gilts were killed and necropsied 22 +/- 1 days later to determine the effect of the virus on their embryos. An equal number of gilts (contro...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01340540

    authors: Mengeling WL,Paul PS,Brown TT

    更新日期:1980-01-01 00:00:00

  • Abortive infection of influenza virus in Ehrlich ascites tumor cells. Unusual fragility of virus particles.

    abstract::Noninfectious virus particles were produced in Ehrlich ascites tumor cells infected intraperitoneally with fowl plague virus. The PFU yield of virus per cell was less than 0.1 and the ratio PFU/HA units in the progeny virus was less than 10(3). The virus particles had the same morphology and size as egg-grown virus bu...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/BF01315278

    authors: Bukrinskaya AG,Gitelman AK,Martynenko VB

    更新日期:1978-01-01 00:00:00

  • Norovirus infection among children with acute gastroenteritis in Recife, Brazil: disease severity is comparable to rotavirus gastroenteritis.

    abstract::Norovirus has captured increasing attention as an agent of childhood diarrhoea. However, it is not known whether norovirus causes as severe diarrhoea as rotavirus, particularly among children in developing countries. In a 1-year study conducted between May 2004 and April 2005 in Recife, Brazil, norovirus was detected ...

    journal_title:Archives of virology

    pub_type: 杂志文章

    doi:10.1007/s00705-008-0060-7

    authors: Nakagomi T,Correia JB,Nakagomi O,Montenegro FM,Cuevas LE,Cunliffe NA,Hart CA

    更新日期:2008-01-01 00:00:00

  • Tetracycline and viruses: a possible treatment for COVID-19?

    abstract::Tetracyclines have been used to treat many bacterial infections. The use of these antibiotics for the treatment of viral diseases dates to the 1960s to 1970s. Over the decades, the effect of tetracyclines on the pathogenesis of viral infections has been demonstrated both clinically and experimentally. Tetracyclines ca...

    journal_title:Archives of virology

    pub_type: 杂志文章,评审

    doi:10.1007/s00705-020-04860-8

    authors: Mosquera-Sulbaran JA,Hernández-Fonseca H

    更新日期:2021-01-01 00:00:00