Abstract:
:Tissues of the central nervous system (CNS) of cynomolgus monkeys were examined by electron microscopy after intraspinal inoculation of enterovirus 71 (E71). A characteristic finding was the appearance of numerous membrane-bound vesicles (Mbvs) in affected motoneurons. Similar Mbvs were also present in E71-infected cynomolgus monkey kidney (CMK) cells in culture. Virus-like particles were found within or around Mbvs in motoneurons as well as in infected CMK cells in culture. Neither Mbvs nor E71 antigens as detected by immunofluorescence were found in supporting tissues, vascular endothelium, or inflammatory cells. Quite similar findings had been seen in poliovirus infections. It was suggested that the appearance of Mbvs in the cytoplasm of motoneuron is the direct results of virus multiplication in E71 infection as in poliovirus infection.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Hashimoto I,Hagiwara A,Uchino Idoi
10.1007/BF01314120subject
Has Abstractpub_date
1985-01-01 00:00:00pages
137-42issue
1-2eissn
0304-8608issn
1432-8798journal_volume
86pub_type
杂志文章abstract::Fowl adenoviruses (FAdVs) are widely distributed in chickens in Poland and throughout the world. FAdV infections have been reported in the United States, Australia, Europe, and the Mediterranean basin. Detection of FAdVs strains is very important from the epidemiological point of view and for monitoring disease outbre...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-015-2635-4
更新日期:2016-01-01 00:00:00
abstract::Bovine leukemia virus (BLV) is a member of the genus Deltaretrovirus of the family Retroviridae and cause a chronic lymphosarcoma, which is extensive in cattle. In yaks (Bos grunniens), the distribution, strains and genetic characteristics of BLV have rarely been studied. The aim of our study was to investigate BLV in...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3658-9
更新日期:2018-03-01 00:00:00
abstract::Two cell lines, CNS-5 and CNS-6, were established by cocultivation of sedimented cells in cerebrospinal fluid (CSF) from two anti-human T-lymphotropic virus type I (HTLV-I) antibody-positive male patients with encephalopathy and HTLV-I-associated myelopathy, respectively, with peripheral blood mononuclear cells from a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311306
更新日期:1991-01-01 00:00:00
abstract::A diagnostic assay to differentiate antibodies induced by foot-and-mouth disease virus (FMDV) infection from those induced by vaccination was developed. The test is an indirect-trapping ELISA which uses a monoclonal antibody to trap the non-structural 3ABC-FMDV polypeptide expressed in E. coli. Experimental and field ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s007050050219
更新日期:1997-01-01 00:00:00
abstract::Bokeloh bat lyssavirus (BBLV) was found in Myotis nattereri for the first time in northeastern France in July 2012. The complete genome sequence of the virus from the infected Natterer's bat was determined by whole-genome sequencing and compared to that of the first BBLV strain isolated in 2010 in Germany and with tho...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1747-y
更新日期:2013-11-01 00:00:00
abstract::Lymphocytic chorimeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), causative agent of Lassa hemorrhagic fever (LHF), belong to the Old World group of the family Arenaviridae. Both viruses have extensive strain diversity and significant variations in lethality and pathogenicity for man and expe...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-004-0385-9
更新日期:2004-12-01 00:00:00
abstract::An F35L mutation in the N-terminal domain of the polymerase acidic protein (PA-Nter), which contains the active site of the endonuclease, has been reported to result in higher polymerase activity in mouse-adapted strains of the 2009 pandemic influenza A H1N1 virus. We modeled wild and mutant complexes of uridine 5'-mo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3681-x
更新日期:2018-04-01 00:00:00
abstract::Multidrug-resistant uropathogenic Escherichia coli (UPEC) is increasing gradually on a worldwide scale. We therefore examined the possibility of bacteriophage (phage) therapy for urinary tract infections (UTIs) caused by the UPEC strains as an alternative to chemotherapy. In addition to the well-known T4 phage, KEP10,...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-0031-4
更新日期:2008-01-01 00:00:00
abstract::An alpha-herpesvirus has recently been associated with green turtle fibropapilloma (FP). To further understand the etiological role of this newfound green turtle herpesvirus (GTHV) in the pathogenesis of FP, expression of GTHV polymerase ( pol) gene was determined in tumors and normal-appearing nontumor tissues and or...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-002-0970-8
更新日期:2003-06-01 00:00:00
abstract::The predominant field strains of Marek's disease virus in Guangxi were clearly different from the vaccine strain CVI988/Rispens based on sequencing of the envelope glycoprotein I (gI), glycoprotein E (gE) and oncogenic meq genes. These differences may be partly responsible for the most recent outbreaks in Guangxi. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-010-0840-8
更新日期:2011-02-01 00:00:00
abstract::We determined the complete genome sequence of a South Korean (SK) isolate of Brugmansia mosaic virus (BruMV), which has recently been proposed to be a member of a new species in the genus Potyvirus. The genomic RNA of BruMV isolate SK is 9781 nucleotides in length (excluding the 3'-terminal poly (A)) and shares comple...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-013-1693-8
更新日期:2013-09-01 00:00:00
abstract::Genomic information about Muscovy duck parvovirus is still limited. In this study, the genome of the pathogenic MDPV strain YY was sequenced. The full-length genome of YY is 5075 nucleotides (nt) long, 57 nt shorter than that of strain FM. Sequence alignment indicates that the 5' and 3' inverted terminal repeats (ITR)...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-2946-0
更新日期:2016-09-01 00:00:00
abstract::We previously reported the VP4 and the VP7 genotypes of the first G6P[14] rotavirus strain (RVA/Human-wt/GHA/M0084/2010/G6P[14]) from the stool of an infant with diarrhoea in Ghana. In the current study, we obtained the complete genome sequences using Illumina MiSeq next-generation sequencing to enable us to determine...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04543-4
更新日期:2020-04-01 00:00:00
abstract::The pathogenicity of 5 different encephalomyocarditis (EMC) virus isolates was investigated in swine fetuses following injection of each virus in utero. Laparotomies were performed on 3 pregnant sows in early mid-third (39-40 days) of gestation and on 5 sows in the late mid-third (70-72 days) of gestation, and groups ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310517
更新日期:1989-01-01 00:00:00
abstract::Human papilloma virus DNA has been examined for heterogeneity by electron microscopy, reassociation kinetics, and restriction endonuclease digestion. No heterogeneity in contour length was detected. The reassociation rate of papilloma DNA isolated from pooled warts was consistent with that expected for a homogeneous, ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314794
更新日期:1977-01-01 00:00:00
abstract::A replication-defective, recombinant Sindbis virus vector was utilized in a novel immunization strategy to induce humoral and cellular responses against hepatitis C virus (HCV). The recombinant vector, pVaXJ-E1E2, expressing the gene for HCV glycoproteins E2 and E1, was constructed by inserting the E1E2 gene into the ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-012-1564-8
更新日期:2013-05-01 00:00:00
abstract::Vector transmission is an important part of the viral infection cycle, yet for many viruses little is known about this process, or how viral sequence variation affects transmission efficacy. Here we examined the effect of substituting genes from the highly transmissible FS577 isolate of citrus tristeza virus (CTV) in ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-3070-x
更新日期:2016-12-01 00:00:00
abstract::Optimal conditions of radial haemolysis in gel (HIG) with Chikungunya (Chik) and Japanese encephalitis (JE) viruses were developed and compared with those of rubella virus. Sheep erythrocytes were found preferable for HIG with Chik and JE viruses, unlike rubella virus, where goose erythrocytes gave best results. Roost...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01320619
更新日期:1980-01-01 00:00:00
abstract::The synthesis of the hemagglutinin (HA) glycoprotein of measles virus was investigated in a persistently infected cell line using a monoclonal anti-HA. The synthesis of the HA protein was shown to be associated with the rough endoplasmic reticulum. The unglycosylated (HA0) apoprotein is synthesized as a 65,000 dalton ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314129
更新日期:1983-01-01 00:00:00
abstract::Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across the world, which has affected more than 2 million people and has led to approximately 150,000 fatal...
journal_title:Archives of virology
pub_type: 杂志文章,评审
doi:10.1007/s00705-020-04768-3
更新日期:2020-11-01 00:00:00
abstract::Hippeastrum chlorotic ringspot virus (HCRV) is a novel tospovirus that was identified in Yunnan Province, China, in 2013. We have sequenced the HCRV L gene, which is 8909 nt long and encodes the RNA-dependent RNA polymerase (2873 amino acids, 330.8 kDa). The HCRV L protein shared highest similarity (89.4 %) with that ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-014-2100-9
更新日期:2014-10-01 00:00:00
abstract::Six synthetic peptides corresponding to regions of bovine enterovirus (BEV), strain VG-5-27, elicited antibodies in mice which reacted with the virus in various assays. These antibodies have been characterised on the basis of their ability to (1) neutralize the virus, (2) bind to the intact virus particle in an immuno...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309681
更新日期:1992-01-01 00:00:00
abstract::Two contigs with high similarity to partitivirus sequences were identified by de novo assembly of sequences obtained by RNA-Seq from a wild brassicaceous plant, Arabidopsis halleri subsp. gemmifera. Here, we report the complete genome sequence of a putative novel partitivirus. Excluding the poly-A tail, it consists of...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-020-04670-y
更新日期:2020-09-01 00:00:00
abstract::Few reports are available on HCV molecular epidemiology among IDUs in Eastern Europe, and none in Montenegro. The aim of this study was to investigate the HCV genotype distribution in Montenegro among IDUs and to perform Bayesian and evolutionary analysis of the most prevalent HCV genotype circulating in this populati...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-017-3224-5
更新日期:2017-06-01 00:00:00
abstract::Human papillomaviruses (HPVs) are responsible for the most common human sexually transmitted viral infections. Infection with high-risk HPVs, particularly HPV16, is associated with the development of cervical cancer. The papillomavirus L1 major capsid protein, the basis of the currently marketed vaccines, self-assembl...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-009-0484-8
更新日期:2009-01-01 00:00:00
abstract::Serological and genetical relationships of three salmonid herpesviruses [strain H-83, OO-7812 strain of Oncorhynchus masou virus (OMV) and Herpesvirus salmonis] were investigated. Although the serological relationships of these viruses were not distinctly demonstrated by cross-neutralization test, cross enzyme-linked ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313818
更新日期:1989-01-01 00:00:00
abstract::Bacterial endotoxins, DNA, live viruses, and viral proteins derived from bacterial and baculovirus (BV) expression vectors employed in recombinant protein production contaminate the final product. Density gradient centrifugation is commonly used to partially purify oligomeric proteins, but impurities from the expressi...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-016-2991-8
更新日期:2016-11-01 00:00:00
abstract::The nucleotide sequence of the 3' terminal region of the Australian isolate of papaya ringspot virus type W [PRSV-W (Aust)] was determined. An open reading frame (864 bp), encoding the putative coat protein gene, occurs upstream of the putative 3' untranslated region (206 bp) and poly(A) tail. A 23 amino acid sequence...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317141
更新日期:1992-01-01 00:00:00
abstract::We previously isolated the monopartite begomovirus tomato leaf curl Java virus (ToLCJAV) and satellite DNAbeta02 from the same naturally infected tomato source in Indonesia. ToLCJAV induced mild leaf curl symptoms in Nicotiana benthamiana plants; DNAbeta02 encoded the betaC1 gene and produced severe leaf curl symptoms...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-007-0957-6
更新日期:2007-01-01 00:00:00
abstract::The value of serologic tests for diagnosis of swine influenza virus (SIV) infection has been diminished by the emergence of new subtypes and by antigenic drift within subtype. The intensive use of vaccination also has complicated interpretation of serology results. Serologic assays are needed that can detect infection...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/s00705-005-0615-9
更新日期:2006-01-01 00:00:00