Abstract：
:The pathogenicity of 5 different encephalomyocarditis (EMC) virus isolates was investigated in swine fetuses following injection of each virus in utero. Laparotomies were performed on 3 pregnant sows in early mid-third (39-40 days) of gestation and on 5 sows in the late mid-third (70-72 days) of gestation, and groups of fetuses were inoculated with different viruses into the amniotic sacs. The uninoculated fetuses served as controls. Thirty-five (71.4%) of 49 infected and 1 of 26 control fetuses were grossly abnormal. Virus was recovered from 18 of 28 infected fetuses and 1 of 16 control fetuses examined. Antibody to EMC virus was detected in all of 14 fetuses infected at 70-72 days of gestation and examined 11-26 days post-infection. The fetal pathogenicity was different depending on the virus strains and the fetal age at the time of virus infection. The EMC ATCC-VR 129 virus was not pathogenic but NVSL-PR, MN-25 and MN-30 were highly pathogenic to the fetuses in both early and late mid-thirds of gestation, while NVSL-MDV was pathogenic to the fetus in early but not in late mid-third of gestation. Possible mechanisms for differences in the pathogenicity between the virus strains are discussed.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Kim HS,Christianson WT,Joo HSdoi
10.1007/BF01310517subject
Has Abstractpub_date
1989-01-01 00:00:00pages
51-7issue
1-2eissn
0304-8608issn
1432-8798journal_volume
109pub_type
杂志文章abstract：:RNA was extracted from 'Hugh Dickson' rose leaves displaying virus-like symptoms in Maryland, USA. Using high-throughput sequencing, we identified a new virus, tentatively named "rose virus R". This virus has a negative-sense, single-stranded RNA genome and exhibits genomic features of a rhabdovirus, including a genom...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04927-6
更新日期：2021-01-04 00:00:00
abstract：:A xenotropic Moloney murine leukemia virus-derived recombinant retrovirus (MMuLVSVnlslacZ) has been utilized to study the mechanism of virus entry into endothelial and epithelial porcine cells. In the genome of this recombinant retrovirus, the nlslacZ reporter gene is under the transcriptional control of both LTR and ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314625
更新日期：1992-01-01 00:00:00
abstract：:A number of viruses and viral proteins interact with a dynamic sub-nuclear structure called the nucleolus. The nucleolus is present during interphase in mammalian cells and is the site of ribosome biogenesis, and has been implicated in controlling regulatory processes such as the cell cycle. Viruses interact with the ...
journal_title：Archives of virology
pub_type： 杂志文章,评审
doi：10.1007/s00705-001-0792-0
更新日期：2002-06-01 00:00:00
abstract：:The distribution of African swine fever virus (ASFV) in whole blood, plasma, red blood cells (RBC) and white blood cell (WbC) sub-populations was determined in pigs infected with virulent virus. Changes in the RBC and WBC populations were also examined. Total WBC counts decreased and RBC numbers remained unchanged dur...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315054
更新日期：1977-01-01 00:00:00
abstract：:Entry processes were compared between dengue-2 (DEN-2) virus and a DEN-2 neutralisation escape mutant virus in baby hamster kidney (BHK) cells. The mutant virus (mu6B2) was resistant to neutralisation by a monoclonal antibody, MAb 6B2. Infection of BHK cells by the wild-type DEN-2 virus resulted in direct penetration ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050561
更新日期：1999-01-01 00:00:00
abstract：:The sequence of prune dwarf ilarvirus (PDV) RNA-1 has been determined; it consists of 3,374 nucleotides and contains a single open reading frame of 3,168 nucleotides. The putative translation product is 1,055 amino acids in length with a calculated molecular mass of 118.9 kDa. Both the nucleic acid and the translated ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050210
更新日期：1997-01-01 00:00:00
abstract：:Cucumber green mottle mosaic virus (CGMMV) is an important pathogen of cucumber (Cucumis sativus). The molecular mechanisms mediating host-pathogen interactions are likely to be strongly influenced by microRNAs (miRNAs), which are known to regulate gene expression during the disease cycle. This study focused on 14 miR...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04152-w
更新日期：2019-04-01 00:00:00
abstract：:Interleukin-2 dependent feline T-lymphoblastoid cells designated as MYA-1 cells were established. The cells were free from exogenous retroviruses and sensitive for replication of feline immunodeficiency virus (FIV). FIV can grow more efficiently in MYA-1 cells than in feline primary peripheral blood mononuclear cells....
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313750
更新日期：1989-01-01 00:00:00
abstract：:At present, there are no effective antiviral treatments available for contagious ecthyma, and rapid diagnosis is therefore critical for effective control of the disease. Recently, the invention of a novel LAMP technique that can rapidly amplify nucleic acids with high specificity and sensitivity under isothermal condi...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1526-1
更新日期：2013-04-01 00:00:00
abstract：:Four epidemic seasons of rotaviruses were studied in Helsinki during 1986-1990. This is the first Scandinavian study, where both electropherotypes and serotypes are determined. Out of 5316 fecal specimens 769 (14.5%) rotavirus positive samples were detected by electron microscopy. Of these, 645 isolates (83.9%) gave a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314964
更新日期：1995-01-01 00:00:00
abstract：:The diagnosis of cytomegalovirus retinitis (CMV-R) is difficult and usually based on clinical criteria or invasive diagnostic procedures. The purpose of this study was to investigate a possible association between CMV-R and specific anti-CMV antibodies in tears. Paired tear and serum samples were obtained from 96 indi...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0813-0
更新日期：2006-12-01 00:00:00
abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) causes a variety of cancers, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman disease (MCD). Host cellular microRNAs (miRNAs) play important post-transcriptional regulatory roles in gene expression and can greatly influence viru...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-017-3478-y
更新日期：2017-11-01 00:00:00
abstract：:Classical swine fever (CSF), caused by the CSF virus (CSFV), is a highly contagious disease in pigs. In Korea, vaccination using a live-attenuated strain (LOM strain) has been used to control the disease. However, parenteral vaccination using a live-attenuated strain still faces a number of problems related to storage...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2182-4
更新日期：2014-12-01 00:00:00
abstract：:A rotavirus-like virus has been isolated from cases of neonatal diarrhoea in piglets. No antigenic relationship with known rotaviruses or with an American strain of a rotavirus-like virus has been demonstrated. Morphologically the virus is similar to known rotaviruses, but it differs in the ability to form syncytia of...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311220
更新日期：1984-01-01 00:00:00
abstract：:Genomic characterization of Norwalk-like human caliciviruses (NLVs) originating from outbreaks and sporadic cases of acute gastroenteritis has revealed surprisingly high levels of diversity, even in the RNA polymerase gene, which is anticipated to be highly conserved. Since information on antigenic relationship is lim...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050020
更新日期：2000-01-01 00:00:00
abstract：:The exact intracellular site of hepatitis A virus (HAV) production is unknown, possibly due to its usually slow and inefficient replication. Using immunocytochemistry and in-situ RT-PCR, we show that in cells infected with the rapidly replicating HAV strain HAS-15, viral proteins and RNA are scattered throughout the c...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050170003
更新日期：2001-12-01 00:00:00
abstract：:The global emergence of canine parvovirus type 2c (CPV-2c) has been well documented. In the present study, 139 rectal swab samples collected from diarrheic dogs living in Vientiane, Laos, in 2016 were tested for the presence of the canine parvovirus (CPV) VP2 gene by PCR. The results showed that 82.73% (115/139) of do...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3212-1
更新日期：2017-05-01 00:00:00
abstract：:The nonstructural rotavirus protein NSP1 binds specifically to viral mRNAs and to interferon regulatory factor 3 (IRF3), inducing IRF3 degradation through a proteasome-dependent pathway. By using a vaccinia virus expression system in mammalian cells, we found that the yield of NSP1 was 8- and 13-fold lower than the vi...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0850-8
更新日期：2007-02-01 00:00:00
abstract：:A coxsackievirus B3 (CVB3) cDNA clone, upon transfection of HeLa cells, produces CVB3 capable of induction of cardiac inflammation in C3H/He mice by day 8 post inoculation (p.i.). Liver and serum are cleared of CVB3 by day 8 p.i., but CVB3 persists in the heart through day 14. The nucleotide sequence and the predicted...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317202
更新日期：1992-01-01 00:00:00
abstract：:Salmonella phages SenALZ1 and SenASZ3, two novel phages infecting Salmonella enterica, were isolated and analyzed. The genomes of these two phages consist of 154,811 and 157,630 base pairs (bp), with G+C contents of 44.56% and 44.74%, respectively. Fifty-nine of 199 open reading frames (ORFs) in the SenALZ1 genome, an...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04183-3
更新日期：2019-05-01 00:00:00
abstract：:We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050056
更新日期：1997-01-01 00:00:00
abstract：:The revised International Code of Virus Classification and Nomenclature [7] followed by the Seventh Report of the International Committee on Taxonomy of Viruses (ICTV) [9] have generated a lot of criticism [2,4-6]. The main causes of criticism are (i) use of monomials instead of non-latinized binomials, as has been pr...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050200051
更新日期：2002-11-01 00:00:00
abstract：:A reversed passive hemagglutination (RPHA) method was developed for the detection of bovine coronavirus in fecal specimens. Sheep erythrocytes fixed with glutaraldehyde, and then treated with tannic acid were coated with anti-bovine coronavirus rabbit antibodies purified by affinity chromatography using bovine coronav...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315291
更新日期：1984-01-01 00:00:00
abstract：:R 61,837, a new antirhinovirus compound, was able to protect several susceptible rhinoviruses against inactivation by mild acidification or heat. This observation strengthens the hypothesis that the drug exerts antiviral activity by a direct interaction with the viral protein capsid to stabilize the particle. However,...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311037
更新日期：1989-01-01 00:00:00
abstract：:A flexuous virus was isolated from cultivated Phaius flavus Lindl. plants in Japan with a latent infection. The virus was assigned to the genus Potexvirus based on morphology and analysis of its complete nucleotide sequence. The genome is 5,816 nucleotides in length, excluding the 3'-terminal poly (A) tail, and contai...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-007-0010-9
更新日期：2008-01-01 00:00:00
abstract：:A full-length cDNA clone of olive latent virus 1 (OLV-1), a member of the genus Necrovirus, family Tombusviridae, was subjected to site-directed mutagenesis, and coat protein gene mutants were constructed. A mutant clone, denoted Delta3297, was obtained by deleting the nucleotide in position 3297, thus inducing a fram...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0767-2
更新日期：2006-10-01 00:00:00
abstract：:The competition between different types of aphthoviruses (foot-and-mouth disease virus [FMDV]) for receptor site utilization was determined. The Southern African Territories (SAT) types of FMDV absorbed poorly to BHK-21 cells as measured by a radioactivity binding assay but grew to relatively high titers on these cell...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01320782
更新日期：1982-01-01 00:00:00
abstract：:The complete genome sequences of isolates of two new bipartite begomoviruses (genus Begomovirus, family Geminiviridae) found infecting common bean in Venezuela are provided. The names proposed for each of these viruses are "bean yellow chlorosis virus" (BYCV) and "bean white chlorosis mosaic virus" (BWCMV). Phylogenet...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1545-y
更新日期：2013-03-01 00:00:00
abstract：:We investigated the potential of Nicotiana benthamiana to express the E7 protein of human papillomavirus 8 (HPV-8), a paradigm genotype among cutaneous HPVs. The protein, modified in its putative pRb-binding domain (E7(QGD)), was transiently expressed in leaves following infiltration with agrobacteria carrying either ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-010-0893-8
更新日期：2011-04-01 00:00:00
abstract：:The complete genome sequences of two grapevine virus L (GVL) isolates collected from the wine grape cultivar Blanc du Bois (Vitis spp.: 'Florida D 6-148'×'Cardinal') in Texas were determined. The two genome sequences (excluding the polyA tail) were each 7594 nucleotide long and 99.7% identical to each other, but they ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-020-04682-8
更新日期：2020-08-01 00:00:00
