Abstract：
:A number of viruses and viral proteins interact with a dynamic sub-nuclear structure called the nucleolus. The nucleolus is present during interphase in mammalian cells and is the site of ribosome biogenesis, and has been implicated in controlling regulatory processes such as the cell cycle. Viruses interact with the nucleolus and its antigens; viral proteins co-localise with factors such as nucleolin, B23 and fibrillarin, and can cause their redistribution during infection. Viruses can use these components as part of their replication process, and also use the nucleolus as a site of replication itself. Many of these properties are not restricted to any particular type of virus or replication mechanism, and examples of these processes can be found in DNA, RNA and retroviruses. Evidence suggests that viruses may target the nucleolus and its components to favour viral transcription, translation and perhaps alter the cell cycle in order to promote virus replication. Autoimmunity to nucleolin and fibrillarin have been associated with a number of diseases, and by targeting the nucleolus and displacing nucleolar antigens, virus infection might play a role in the initiation of these conditions.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Hiscox JAdoi
10.1007/s00705-001-0792-0keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
1077-89issue
6eissn
0304-8608issn
1432-8798journal_volume
147pub_type
杂志文章,评审abstract：:We analyzed retrospectively a relative risk of measles attacks in vaccinated vs. unvaccinated students using two independent outbreaks in Japan. The first involved 33/328 (10%) students where 64% students and 30% measles cases had been vaccinated. The second involved 27/241 (11%) students where 81% students and 48% me...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309868
更新日期：1995-01-01 00:00:00
abstract：:Porcine epidemic diarrhea virus (PEDV) causes acute diarrhea and dehydration with high mortality rates in swine. It has become increasingly problematic in China. Since the nucleocapsid (N) protein is highly conserved, it is a candidate protein for early diagnosis and vaccine development. In this study, the N genes of ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1592-4
更新日期：2013-06-01 00:00:00
abstract：:Human diploid BAMB cells with epitheloid morphology, which had been derived from amniotic fluid cells, were capable of supporting the replication of human cytomegalovirus (CMV), without prior treatment of the cells with halogenated pyrimidines. The growth of this virus in BAMB cells and in human diploid fibroblastoid ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315617
更新日期：1976-01-01 00:00:00
abstract：:Four epidemic seasons of rotaviruses were studied in Helsinki during 1986-1990. This is the first Scandinavian study, where both electropherotypes and serotypes are determined. Out of 5316 fecal specimens 769 (14.5%) rotavirus positive samples were detected by electron microscopy. Of these, 645 isolates (83.9%) gave a...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314964
更新日期：1995-01-01 00:00:00
abstract：:During the epidemic outbreak in the region of Greifswald in the winter 1974/75, we found influenza virus variants which showed differences in the electrophoretic mobility of HA. Among the 25 isolates 13 were of slower and 12 of higher mobility. HA1 of 6 isolates was studied by determining the number of the carbohydrat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01310484
更新日期：1991-01-01 00:00:00
abstract：:Infectivity of non-occluded particles of nuclear polyhedrosis virus infecting Galleria mellonella L. was determined with bioassay technique in vivo and with plaque assay method in vitro using SCLd 135 (Quiot) established cell culture. A plaque-forming virus unit corresponds to about 50 ID50 for Galleria larvae injecte...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01315023
更新日期：1979-01-01 00:00:00
abstract：:The acid-extractable leaf proteins of potato spindle tuber viroid (PSTV) infected tomato plants were analysed electrophoretically on polyacrylamide gels. The most prominent alteration found during disease development was the appearance of a "pathogenesis-related" protein with an apparent molecular weight of 14,000 (ca...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309998
更新日期：1984-01-01 00:00:00
abstract：:In this cross-sectional study, we evaluated the efficiency of the plasma of 38 antiretroviral-naïve HIV-1-infected children from northern India against a standard panel of pseudoviruses (3 clade C and 3 clade B) by TZM-bl assay. Neutralization potential was observed to a variable extent, with a potency ranging up to r...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-012-1357-0
更新日期：2012-09-01 00:00:00
abstract：:A polymerase chain reaction (PCR) based assay capable of detecting and differentiating seven strains of equine arteritis virus (EAV) from around the world was developed. The primers for the PCR were chosen from the ORF6 gene encoding the unglycosylated membrane protein (M). Viral RNA from cell culture fluids infected ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322675
更新日期：1995-01-01 00:00:00
abstract：:In guinea-pig infected with foot-and-mouth disease virus (FMDV), Langerhans cells in the foot pads increase in number and show viral antigens 24 hours post-inoculation, preceding appearance of virus in epithelial cells and vesiculation. This observation suggests that Langerhans cells may be engaged in virus transport ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01309929
更新日期：1985-01-01 00:00:00
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journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04487-4
更新日期：2020-02-01 00:00:00
abstract：:Here, we report a novel virulent P2-like bacteriophage, R18C, isolated from rabbit faeces, which, in addition to Escherichia coli K-12 strains, was able to be propagated on Citrobacter rodentium strain ICC169 and a range of Shigella sonnei strains with high efficiency of plating (EOP). It represents the first lytic ba...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-019-04424-5
更新日期：2019-12-01 00:00:00
abstract：:Persistent infections with high-risk human papillomaviruses (HR-HPVs) are linked to the development of cervical cancer due to a deregulation of the productive viral cycle in the host cell, leading to cell transformation. The E2 viral protein is expressed early during an HPV infection and regulates viral replication an...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-018-04124-6
更新日期：2019-07-01 00:00:00
abstract：:We focused on the role of membrane bound sugar residues in the infection of fibroblasts and monocyte-like cells with human cytomegalovirus (HCMV). Treatment of phorbol 12-myristate 13-acetate (PMA) differentiated monocyte-like cells THP-1 or human fibroblasts MRC-5 with lectins specific for N-acetylneuraminic acid (Ne...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01322663
更新日期：1995-01-01 00:00:00
abstract：:Styrian oil pumpkin seedlings (Cucurbita pepo L. subsp. pepo var. styriaca GREB: .) were treated for 48 h with 1 mM OTC (L-2-oxothiazolidine-4-carboxylic acid) in order to artificially increase cellular glutathione content. They were inoculated with zucchini yellow mosaic virus (ZYMV) 10 days later. The effects of OTC...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-006-0880-2
更新日期：2007-01-01 00:00:00
abstract：:Influenza virus A/WSN/33 forms large plaques (> 3 mm diameter) on MDCK cells whereas A/Aichi/2/68 forms only small plaques (< 1 mm diameter). Fast growing reassortants (AWM), isolated by mixed infection of MDCK cells with these two virus strains in the presence of anti-WSN antibodies, all carried the M gene from WSN. ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01313769
更新日期：1993-01-01 00:00:00
abstract：:We have compared the RNA synthesis of alfalfa mosaic virus in complete (by RNAs 1, 2 and 3) and incomplete infections (by RNAs 1 and 2) of cowpea protoplasts. Both viral RNA polymerase activity and accumulation of viral RNA were measured. By annealing RNA in solution with 32P-labelled probes of plus and minus polarity...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050305
更新日期：1998-01-01 00:00:00
abstract：:Rabbit convalescent and hyperimmune sera, human patient and blood donor sera, as well as cerebrospinal fluids of humans with herpes simplex virus encephalitis all recognize similar major antigenic components in herpes simplex virus infected rabbit or human cells as shown by electrophoretic analysis of immunoprecipitat...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314855
更新日期：1977-01-01 00:00:00
abstract：:Foot-and-mouth disease (FMD) is a highly contagious viral disease of transboundary importance. In India, since the launch of the FMD control programme, there has been a substantial increase in the vaccinated bovine population. In this scenario, there is a need for additional locally developed non-structural protein (N...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-013-1973-3
更新日期：2014-07-01 00:00:00
abstract：:The complete genome sequence of an isolate of euphorbia ringspot virus (EuRSV) was determined by deep sequencing and rapid amplification of cDNA ends (RACE) RT-PCR. It has an RNA genome of 10,154 nucleotides in size, excluding the poly(A) tail, and encodes a polyprotein of 3265 amino acids. Phylogenetic analysis from ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-016-3087-1
更新日期：2017-01-01 00:00:00
abstract：:Lymphocytic chorimeningitis virus (LCMV), the prototype arenavirus, and Lassa virus (LASV), causative agent of Lassa hemorrhagic fever (LHF), belong to the Old World group of the family Arenaviridae. Both viruses have extensive strain diversity and significant variations in lethality and pathogenicity for man and expe...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-004-0385-9
更新日期：2004-12-01 00:00:00
abstract：:The ability of human fibroblast interferon to suppress colony formation and papovavirus T-antigen expression in six human tumor cell lines did not appear to correlate with their content of chromosomes 16 and 21. Additional factors or chromosomes may be involved in the manifestation of interferon action in aneuploid ce...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01317505
更新日期：1979-01-01 00:00:00
abstract：:Dengue and chikungunya viruses co-circulate and cause infections that start with similar symptoms but progress to radically different outcomes. Therefore, an early diagnostic test that can differentiate between the two is needed. A single-step multiplex real-time RT-PCR assay was developed that can simultaneously dete...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-014-2217-x
更新日期：2015-01-01 00:00:00
abstract：:In order to prepare H5N1 influenza virus vaccine, the hemagglutinins (HAs) of 14 H5 virus isolates from water birds in Asia were antigenically and genetically analyzed. Phylogenetic analysis of the H5 HA genes revealed that 13 isolates belong to Eurasian and the other one to North American lineages. Each of the deduce...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-008-0226-3
更新日期：2008-01-01 00:00:00
abstract：:Exposure of human lung fibroblasts to human cytomegalovirus (HCMV) stimulated a rapid increase in the release of [3H] from cells prelabelled with radiolabelled arachidonic acid ([3H]AA). Maximum stimulation of [3H] release was observed at 20 min postinfection and was quantitatively similar to that induced by the tumor...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01316678
更新日期：1990-01-01 00:00:00
abstract：:Rice transitory yellowing virus (RTYV), a member of the genus Nucleorhabdovirus, is closely related to or synonymous with rice yellow stunt virus (RYSV). To clarify the relationship between RTYV and RYSV, we determined the nucleotide sequence of the RTYV genome. The RTYV genome consists of 14,029 nucleotides. The over...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-009-0557-8
更新日期：2010-02-01 00:00:00
abstract：:Using a one-step model for cell-to-cell transmission of HIV infection we have identified two distinct phases of HIV RNA synthesis. The first phase (4 h-12 h p.i.) was marked by an increase in only the full-length 9 kb RNA, while the second phase (24 h p.i. onwards) comprised a significant increase in the levels of all...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s007050050429
更新日期：1998-01-01 00:00:00
abstract：:The genomes of a large number of highly diverse novel circular DNA viruses from a wide range of sources have been characterised in recent years, including circular single-stranded DNA (ssDNA) viruses that share similarities with plant-infecting ssDNA viruses of the family Geminiviridae. Here, we describe six novel cir...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/s00705-015-2358-6
更新日期：2015-05-01 00:00:00
abstract：:A xenotropic Moloney murine leukemia virus-derived recombinant retrovirus (MMuLVSVnlslacZ) has been utilized to study the mechanism of virus entry into endothelial and epithelial porcine cells. In the genome of this recombinant retrovirus, the nlslacZ reporter gene is under the transcriptional control of both LTR and ...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01314625
更新日期：1992-01-01 00:00:00
abstract：:R 61,837, a new antirhinovirus compound, was able to protect several susceptible rhinoviruses against inactivation by mild acidification or heat. This observation strengthens the hypothesis that the drug exerts antiviral activity by a direct interaction with the viral protein capsid to stabilize the particle. However,...
journal_title：Archives of virology
pub_type： 杂志文章
doi：10.1007/BF01311037
更新日期：1989-01-01 00:00:00
