Abstract:
:Various properties have been evaluated for the binding to tissue culture substrata of proteolytic fragments of human plasma or cellular fibronectins containing complementary sequences from the individual and alternatively spliced chains, since related fragments are known to yield differing adhesive responses from cells. These studies utilize ELISA methods and a polyclonal antiserum directed to human pFN for direct measurement or an occupancy test utilizing anti-albumin. Very related fragments (with or without an extra type III homology unit or extra domaina or b) have significantly different properties in substratum binding and such differences provide a partial explanation for alteration of cellular adhesive responses on such fragments.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Lewandowska K,Kaetzel CS,Zardi L,Culp LAdoi
10.1016/0014-5793(88)80166-2subject
Has Abstractpub_date
1988-09-12 00:00:00pages
35-9issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(88)80166-2journal_volume
237pub_type
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