Abstract:
:The substrate specificity of purified PKC-alpha, -beta and -gamma has been investigated. A series of synthetic peptides based upon the sequence surrounding serine-7 in glycogen synthase were generated and used to determine the basic residue requirements of these PKC isotypes. While PKC-alpha and -beta are indistinguishable in their phosphorylation of these peptides, PKC-gamma shows a distinct specificity profile for these synthetic substrates.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Marais RM,Nguyen O,Woodgett JR,Parker PJdoi
10.1016/0014-5793(90)80831-3subject
Has Abstractpub_date
1990-12-17 00:00:00pages
151-5issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(90)80831-3journal_volume
277pub_type
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