Abstract:
:Hypohalous acids are poor one-electron oxidizing agents, such that reactions with hydrogen peroxide to yield radical species are not feasible. However, the oxidation of superoxide by hypohalous acids can be a source of hydroxyl or haline radicals. The oxidation of nitrogen monoxide by hypochlorous acid is favourable, but in all likelihood cannot compete with the diffusion-controlled reaction with superoxide to yield peroxynitrite. The reaction of the latter with hypochlorous acid may lead to nitrosyl chloride, a strongly oxidizing agent [Eo'(NOCl/NO., Cl) = 1.0 V] that is capable of nitrosylating organic compounds and thereby generating mutagens or promutagens.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Koppenol WHdoi
10.1016/0014-5793(94)00494-3subject
Has Abstractpub_date
1994-06-20 00:00:00pages
5-8issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(94)00494-3journal_volume
347pub_type
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