Abstract:
:1,2-Didecanoylglycerol (diC10) is taken up by human platelets and sequentially converted to 1,2-didecanoylphosphatidic acid (PA10) and 1,2-didecanoylphosphatidylinositol (PI10). Agents that increase cyclic AMP in platelets, such as prostacyclin and forskolin, sequentially convert diC10 to PA10 and PI10. They decrease formation of PA10 with a parallel accumulation of PI10. This might reflect an inhibition of phosphatidylinositol kinase.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Lapetina EGdoi
10.1016/0014-5793(86)80141-7subject
Has Abstractpub_date
1986-01-20 00:00:00pages
111-4issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(86)80141-7journal_volume
195pub_type
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