The constituents of storage granules in the dermal glands of Xenopus laevis. Structure of a basic polypeptide deduced from cloned cDNA.

Abstract:

:Mature dermal glands of Xenopus laevis contain storage granules with a characteristic ellipsoid shape. A few major proteins are present in these granules, including two with the same amino-terminal sequence and apparent molecular masses of 26 and 28 kDa. Using antibodies against these proteins, positive clones were isolated from a cDNA expression library prepared from skin of X. laevis. One cDNA encodes a preprotein with a typical signal sequence and a mature part of 187 amino acids. The protein shows internal homology at both the amino and carboxyl end. The latter part has a very high content of basic amino acids.

journal_name

FEBS Lett

journal_title

FEBS letters

authors

Berger H,Kreil G

doi

10.1016/0014-5793(89)80644-1

subject

Has Abstract

pub_date

1989-06-05 00:00:00

pages

293-6

issue

2

eissn

0014-5793

issn

1873-3468

pii

0014-5793(89)80644-1

journal_volume

249

pub_type

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