Abstract:
:Photon correlation spectroscopy demonstrated for the first time that co-purified meningococcal TbpA+B form a complex in solution. This structure bound hTf and the resultant species underwent partial dissociation after exposure to additional hTf or following prolonged incubation. Purified TbpA and TbpB had similar apparent sizes but showed distinctive size profiles suggesting that TbpA forms a largely homogeneous population while TbpB may produce more variable particle sizes under these conditions.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Boulton IC,Gorringe AR,Carr RJ,Gorinsky B,Joannou CL,Evans RWdoi
10.1016/s0014-5793(97)01025-9subject
Has Abstractpub_date
1997-09-08 00:00:00pages
409-13issue
2eissn
0014-5793issn
1873-3468pii
S0014-5793(97)01025-9journal_volume
414pub_type
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