Abstract:
:Holocytochrome c synthase (HCCS) attaches heme covalently to mitochondrial respiratory cytochromes c. Little is known about the reaction of heme attachment to apocytochromes c by HCCS, although recently it has been established that the CXXCH motif and the N-terminus of the apocytochrome polypeptide are important protein-protein recognition motifs. Here, we explore further the important features of the N-terminal sequence and investigate what variations in the CXXCH residues are productively recognised by HCCS in its substrate.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Zhang Y,Stevens JM,Ferguson SJdoi
10.1016/j.febslet.2014.07.026subject
Has Abstractpub_date
2014-09-17 00:00:00pages
3367-74issue
18eissn
0014-5793issn
1873-3468pii
S0014-5793(14)00575-4journal_volume
588pub_type
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