Abstract:
:Several of the recently described leucocyte surface (glyco)-proteins with significant amino acid sequence similarity (human CD9, CD37, CD53, CD63, TAPA-1, CO-029 and R2 and several homologues of other species) are distinguished by the polypeptide chain apparently four times crossing the membrane. Although the biological role of none of these molecules is known, their structure, associations with other membrane components and the effects of specific monoclonal antibodies suggest that they may constitute a family of ion channels or other transport molecules.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Horejsí V,Vlcek Cdoi
10.1016/0014-5793(91)80988-fsubject
Has Abstractpub_date
1991-08-19 00:00:00pages
1-4issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(91)80988-Fjournal_volume
288pub_type
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