Grass pollen counts, air pollution levels and allergic rhinitis severity.

abstract：:Recent data suggest that stem cell factor (SCF or c-kit ligand, KL) is a major regulator of human mast cells (MCs). In the present study, MCs derived from the lung (n = 8), uterus (n = 14) and heart (n = 4) were analyzed for expression of c-kit receptor and for responses to recombinant SCF. MCs of all organs tested we...

journal_title：International archives of allergy and immunology

authors： Sperr WR,Czerwenka K,Mundigler G,Müller MR,Semper H,Klappacher G,Glogar HD,Lechner K,Valent P

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The aetiology of chronic urticaria is heterogeneous. Physical urticaria (PU) is estimated at around 35%, autoimmune urticaria (AIU) at 25% and chronic idiopathic urticaria (CIU) at 35% of all chronic urticaria cases. METHODS:Differences in clinical and laboratory parameters among AIU, PU and CIU groups were...

journal_title：International archives of allergy and immunology

authors： Irinyi B,Széles G,Gyimesi E,Tumpek J,Herédi E,Dimitrios G,Adány R,Hunyadi J,Szegedi A

更新日期：2007-01-01 00:00:00

abstract：:A previous study described clinical and pathological manifestations observed in 49 chimeras produced by replacing a small fragment of the neural tube of a chicken embryo by a similar fragment from a Japanese quail embryo. Predominant antibodies in sera of these birds were directed against xenogeneic antigens which are...

journal_title：International archives of allergy and immunology

authors： Yang G,Albini B,Milgrom F

更新日期：1992-01-01 00:00:00

abstract：:Preferential eosinophil accumulation is characteristic of airway inflammation in asthma. Although little is known about its mechanism, the effect of a sialyl Lewis X analog on airway eosinophilia was examined in a guinea-pig model of asthma. Guinea-pigs were sensitized by repeated inhalation of ovalbumin. After a sing...

journal_title：International archives of allergy and immunology

authors： Sagara H,Ra C,Okada T,Shinohara S,Fukuda T,Okumura K,Makino S

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Lactation is associated with an inhibited hypothalamic-pituitary-adrenal axis response to physical and psychological stress in women and female rats. However, suckling also improved mood and calmness in nonatopic lactating women. Relaxation by humor reduced allergen-induced skin wheal responses, while variou...

journal_title：International archives of allergy and immunology

authors： Kimata H

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Several studies have examined the relationship of asthma with serum dyslipidemia and reported positive, negative or no association. Most studies were limited by their cross-sectional design and the wide age range of the participants. In a cohort of children in Cyprus, we explored the association of asthma wi...

journal_title：International archives of allergy and immunology

authors： Yiallouros PK,Savva SC,Kolokotroni O,Dima K,Zerva A,Kouis P,Bousquet J,Middleton N

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species (ROS) and eosinophilic granule proteins such as eosinophil-derived neurotoxin (EDN) are known to damage bronchial tissue and cause airway hyperresponsiveness (AHR) in asthma. Hepatocyte growth factor (HGF) regulates various biological activities and is known to be a multifunctional fa...

journal_title：International archives of allergy and immunology

authors： Ito W,Takeda M,Fujita M,Kamada Y,Kato H,Chiba T,Yamaguchi K,Ueki S,Kayaba H,Kanehiro A,Chihara J

更新日期：2008-01-01 00:00:00

abstract：:Superoxide (O2-) and nitric oxide (NO) production by polymorphonuclear leukocyte (PMNs) and monocytes in patients with liver cirrhosis were evaluated. PMNs obtained from cirrhotic patients were less effective than those from controls in producing O2- after stimulation with opsonized zymosan, while they were more effec...

journal_title：International archives of allergy and immunology

authors： Masini E,Mugnai L,Foschi M,Laffi G,Gentilini P,Mannaioni PF

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The European tick, Argas reflexus, is an urban pest parasitizing urban pigeons and may cause a wide range of allergic reactions. METHODS:Specific IgE to A. reflexus, SDS-PAGE and IgE immunoblotting, performed with tick extract, were carried out in the sera of 6 patients who reported allergic reactions after...

journal_title：International archives of allergy and immunology

authors： Rolla G,Nebiolo F,Marsico P,Guida G,Bigo P,Riva G,Zanotta S

更新日期：2004-12-01 00:00:00

abstract：:The primary acquired lactase deficiency of the adult is known to cause various disturbances in the gastrointestinal tract while extraintestinal symptoms are unusual. Here we report on a histologically proven chronic eczema requiring corticosteroid treatment for several months. It was obviously induced by a concomitant...

journal_title：International archives of allergy and immunology

authors： Grimbacher B,Peters T,Peter HH

更新日期：1997-08-01 00:00:00

abstract：:The clear recognition that asthma has an inflammatory basis has led to a search for genetic and environmental causes. Genetic linkage studies provide evidence for allelic association between polymorphic markers of interleukin-9 on chromosome 5 and a principal component of the allergic phenotype, log IgE. Further studi...

journal_title：International archives of allergy and immunology

authors： Holgate ST,Church MK,Howarth PH,Morton EN,Frew AJ,Djukanović R

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Subcutaneous immunotherapy for respiratory allergy has shown a long lasting efficacy after its discontinuation, whereas evidence in the case of sublingual immunotherapy (SLIT) is weak. This retrospective study evaluates whether SLIT exerts a long-lasting effect and whether it relates to its duration. METHOD...

journal_title：International archives of allergy and immunology

authors： Marogna M,Bruno M,Massolo A,Falagiani P

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Mountain cedar (Juniperus ashei) pollen commonly causes a winter time allergic rhinitis in the central USA. Jun a 1 is the dominant allergenic protein, but biologically active recombinant Jun a 1 has not been successfully expressed, despite numerous attempts with several expression systems. METHOD:Jun a 1 c...

journal_title：International archives of allergy and immunology

authors： Liu Z,Bhattacharyya S,Ning B,Midoro-Horiuti T,Czerwinski EW,Goldblum RM,Mort A,Kearney CM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Nasal polyps are a common health problem that can significantly impact the quality of life. OBJECTIVE:To analyze the impact of allergy and peripheral eosinophils (EOS) on the morbidity of chronic rhinosinusitis with nasal polyps (CRSwNP) in Northwest China. METHODS:A retrospective cohort of 323 patients wh...

journal_title：International archives of allergy and immunology

authors： Chen F,Wen L,Qiao L,Shi Z,Xue T,Chen X,Li X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:To understand how the high-affinity IgE receptor (FcepsilonRI) communicates with downstream effectors, we focused on exploring the functional importance of the FcepsilonRI-mediated formation and localization of a signaling complex that contains the hematopoietic cell-specific scaffolding protein linker for a...

journal_title：International archives of allergy and immunology

authors： Rivera J,Arudchandran R,Gonzalez-Espinosa C,Manetz TS,Xirasagar S

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Basophils and mast cells are important initiator/effector cells capable of rapidly responding to IgE-mediated stimulation, but the precise mechanisms regulating their functions in vivo have not been fully identified. In this study, we assessed whether low levels of antigen can modulate activation of basophil...

journal_title：International archives of allergy and immunology

authors： Koketsu R,Yamaguchi M,Suzukawa M,Tanaka Y,Tashimo H,Arai H,Nagase H,Matsumoto K,Saito H,Ra C,Yamamoto K,Ohta K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Clinically it is recognized that tree nut allergies such as hazelnut allergy are not usually outgrown. Specific mechanisms underlying the persistence of such food allergies are incompletely understood. Here we studied the natural history and the long-term immune and clinical characteristics of hazelnut aller...

journal_title：International archives of allergy and immunology

authors： Gonipeta B,Parvataneni S,Paruchuri P,Gangur V

更新日期：2010-01-01 00:00:00

abstract：:Interaction between vascular cell adhesion molecule-1 (VCAM-1) on endothelial cells and CD49d molecules on eosinophils is thought to mediate the selective infiltration of eosinophils into inflamed tissues in allergic disease. IL-4 and TNF-alpha are associated with allergic conditions, and they have been shown to selec...

journal_title：International archives of allergy and immunology

authors： Saito H,Shimizu H,Mita H,Maeda Y,Akiyama K

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:High antibiotic prescribing rates for adults with an asthma exacerbation have been reported in developed countries, but few studies have assessed the variation of antibiotic and adjunctive treatment in the routine care of children. OBJECTIVE:We evaluated the trends in health resource utilization for childre...

journal_title：International archives of allergy and immunology

authors： Okubo Y,Horimukai K,Michihata N,Morita K,Matsui H,Fushimi K,Yasunaga H

更新日期：2020-01-01 00:00:00

abstract：:Bed bugs may cause mild to severe cutaneous reactions. We studied the ability of bed bug salivary extract (SGE) to induce inflammatory reactions responsible for cutaneous manifestations and found that SGE stimulated the production of several potent chemokines and cytokines from macrophages. Chemokines induced by SGE i...

journal_title：International archives of allergy and immunology

authors： Goddard J,Hasenkampf N,Edwards KT,de Shazo R,Embers ME

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cry j 1 and Cry j 2 are thought to be the major allergens of Japanese cedar pollen. HLA class II types capable of presenting T-cell epitopes in both allergens and their role in induction of T-cell subsets are not well known. METHODS:CD4+ T (Th)-cell clones (TCCs) specific to either Cry j 1 or Cry j 2 were g...

journal_title：International archives of allergy and immunology

authors： Sone T,Morikubo K,Shimizu K,Komiyama N,Tsunoo H,Kino K

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa phospholipase C (PLC) is a critical component in the pathogenesis of severe P. aeruginosa infections. However, P. aeruginosa can produce a hemolytic (PLC-H) as well as a nonhemolytic (PLC-N) variant, both having a MW of about 77 kD. In the past, studies did not distinguish between both...

journal_title：International archives of allergy and immunology

authors： König B,Vasil ML,König W

更新日期：1997-02-01 00:00:00

abstract：:Der f2 protein in a highly antigenic form was directly expressed in bacteria. Plasmid pFLU11 derived from pKK233-2 was designed to express methionyl-Der f2 under the control of the trc promoter and it has the replication origin of pUC118 instead of its original to increase the copy number. This expression plasmid dire...

journal_title：International archives of allergy and immunology

authors： Iwamoto N,Nishiyama C,Yasuhara T,Saito A,Yuuki T,Okumura Y,Okudaira H

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that administration of probiotics in vitro can stimulate regulatory and Th1 immune responses. We studied both the in vitro immunological effects of probiotics and the ex vivo immunological effects after oral administration of probiotics in children with food allergy, a Th2-mediated d...

journal_title：International archives of allergy and immunology

authors： Flinterman AE,Knol EF,van Ieperen-van Dijk AG,Timmerman HM,Knulst AC,Bruijnzeel-Koomen CA,Pasmans SG,van Hoffen E

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:In developed countries, increasing food allergy prevalence and concern regarding food allergies have been reported. Although the use of complementary and alternative medicine (CAM) for the treatment of allergic diseases has increased in some Western countries, the actual proportion and patterns of CAM use fo...

journal_title：International archives of allergy and immunology

authors： Nakano T,Shimojo N,Okamoto Y,Ebisawa M,Kurihara K,Hoshioka A,Yamaguchi K,Ito K,Fujisawa T,Kameda M,Suehiro Y,Ogura H,Shibata R,Suzuki S,Takahashi Y,Ikeda M,Kohno Y

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Measurement of fractional exhaled nitric oxide (FENO) is useful in assessing eosinophilic airway inflammation. Smoking may modify airway inflammation and reduce FENO levels, compromising the diagnostic value of FENO in smokers. How smoking influences FENO in atopic versus nonatopic asthmatics is unknown. The...

journal_title：International archives of allergy and immunology

authors： Rouhos A,Ekroos H,Karjalainen J,Sarna S,Haahtela T,Sovijärvi AR

更新日期：2010-01-01 00:00:00

abstract：:IL-3-dependent, murine mast cell lines derived from embryonic yolk sac precursors display a tumoricidal activity that is blocked by antibodies against tumor necrosis factor-alpha, indicating that this cytokine is the major mediator involved in the cytotoxic activity of the cultured mast cell lines. Further, cholera to...

journal_title：International archives of allergy and immunology

authors： Manning JK,Malkovsky M,Meager A

更新日期：1992-01-01 00:00:00

abstract：:We studied the binding activities of IgE, IgG and IgA antibodies in patients with allergy to hen's egg white against two different ovalbumin (OVA) preparations, which were physically or chemically denatured OVA and enzyme-digested OVA fragments. The binding activities of IgE antibodies to these OVA preparations with t...

journal_title：International archives of allergy and immunology

authors： Honma K,Kohno Y,Saito K,Shimojo N,Tsunoo H,Niimi H

更新日期：1994-01-01 00:00:00

abstract：:Two cDNA clones named P9* and P1* of 794 and 631 bp, respectively, were isolated from a lambda ZAP cDNA expression library using Parietaria judaica (Pj) pollen-specific IgE antibodies from a pool of sera (n = 23) of patients allergic to Pj. Sequence analysis showed open reading frames of 176 and 138 amino acids. Both ...

journal_title：International archives of allergy and immunology

authors： Duro G,Colombo P,Assunta Costa M,Izzo V,Porcasi R,Di Fiore R,Locorotondo G,Cocchiara R,Geraci D

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is increasing among the elderly. Staphylococcus aureus colonization is one of the most important aggravating factors in AD. OBJECTIVE:This study analyses the clinical features of AD in elderly patients and determines the pathogenic roles of staphylococcal superantigens in AD with low ...

journal_title：International archives of allergy and immunology

authors： Bozek A,Fisher A,Filipowska B,Mazur B,Jarzab J

更新日期：2012-01-01 00:00:00