Hepatocyte growth factor suppresses production of reactive oxygen species and release of eosinophil-derived neurotoxin from human eosinophils.

abstract：:Accumulation and activation of eosinophils in tissue are critical events in the allergic inflammatory response and adhesion molecules play important roles in this process. We previously demonstrated that human eosinophils expressed a nuclear receptor, peroxisome proliferator-activated receptor gamma (PPARgamma), and t...

journal_title：International archives of allergy and immunology

authors： Hirasawa H,Chiba T,Ueki S,Kamada Y,Ito W,Takeda M,Fujita M,Kato H,Kayaba H,Chihara J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that administration of probiotics in vitro can stimulate regulatory and Th1 immune responses. We studied both the in vitro immunological effects of probiotics and the ex vivo immunological effects after oral administration of probiotics in children with food allergy, a Th2-mediated d...

journal_title：International archives of allergy and immunology

authors： Flinterman AE,Knol EF,van Ieperen-van Dijk AG,Timmerman HM,Knulst AC,Bruijnzeel-Koomen CA,Pasmans SG,van Hoffen E

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Venom immunotherapy (VIT) is considered to be the gold-standard treatment for patients with Hymenoptera venom allergy. Data regarding VIT in bee venom (BV) allergic patients are scarce. AIM:The aim of this study was to evaluate the outcome of VIT in patients with exclusive BV allergy and to try to define ...

journal_title：International archives of allergy and immunology

authors： Rosman Y,Nashef F,Cohen-Engler A,Meir-Shafrir K,Lachover-Roth I,Confino-Cohen R

更新日期：2019-01-01 00:00:00

abstract：:Recent data suggest that stem cell factor (SCF or c-kit ligand, KL) is a major regulator of human mast cells (MCs). In the present study, MCs derived from the lung (n = 8), uterus (n = 14) and heart (n = 4) were analyzed for expression of c-kit receptor and for responses to recombinant SCF. MCs of all organs tested we...

journal_title：International archives of allergy and immunology

authors： Sperr WR,Czerwenka K,Mundigler G,Müller MR,Semper H,Klappacher G,Glogar HD,Lechner K,Valent P

更新日期：1993-01-01 00:00:00

abstract：:Peritoneal mast cells of Syrian hamsters release histamine to the action of concanavalin A (Con A) in dose-dependent fashion. The rate of release was very rapid in the first seconds of cell activation and completed in 60 s after the challenge. Morphological changes concomitant to the lectin treatment, followed by elec...

journal_title：International archives of allergy and immunology

authors： Wyczolkowska J,Rydzynski K,Prouvost-Danon A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) can trigger immediate-type hypersensitivity reactions (HSRs). Three main patterns of cross-reactivity have been identified: reactions to a single PPI, selective cross-reactions, and cross-reactions with all PPIs. Several hypotheses have been advanced, but no consensus has been r...

journal_title：International archives of allergy and immunology

authors： Tourillon C,Mahe J,Baron A,Lambert A,Yélehé-Okouma M,Veyrac G,Jolliet P

更新日期：2019-01-01 00:00:00

abstract：:A high-dose, accelerated escalation schedule during subcutaneous allergen-specific immunotherapy (AIT) is safe and well-tolerated in adults. However, there are no data in children and adolescents. The aim of the present trial was to assess safety and tolerability of an accelerated dose escalation schedule of an AIT wi...

journal_title：International archives of allergy and immunology

authors： Bovermann X,Ricklefs I,Vogelberg C,Klimek L,Kopp MV

更新日期：2021-01-27 00:00:00

abstract：BACKGROUND:Most patients with chronic spontaneous urticaria (CSU) exhibit recurrent angioedema. As of yet, the pathogenesis of angioedema in CSU is largely unclear, especially when angioedema occurs in patients who do not develop wheals. Over the past years, we and others have repeatedly observed that patients with rec...

journal_title：International archives of allergy and immunology

authors： Rogala B,Bozek A,Glück J,Rymarczyk B,Jarzab J,Maurer M

更新日期：2014-01-01 00:00:00

abstract：:Long-term birth cohort studies are essential to understanding the life course and childhood predictors of allergy and the complex interplay between genes and the environment (including lifestyle and socioeconomic determinants). Over 100 cohorts focusing on asthma and allergy have been initiated in the world over the p...

journal_title：International archives of allergy and immunology

authors： Bousquet J,Anto J,Sunyer J,Nieuwenhuijsen M,Vrijheid M,Keil T,MeDALL Study Group.,CHICOS Study Group.,ENRIECO Study Group.,GA²LEN Study Group.

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:We previously showed that immunization of mice with plasmid DNA (pDNA) encoding the Escherichia coli beta-galactosidase gene (pCMV-LacZ) induces a Th1 response, whereas beta-galactosidase (beta-gal) in saline or alum induces a Th2 response. Furthermore, the Th1 response dominates over the Th2 response and do...

journal_title：International archives of allergy and immunology

authors： Lee DJ,Tighe H,Corr M,Roman M,Carson DA,Spiegelberg HL,Raz E

更新日期：1997-05-01 00:00:00

abstract：:Allergic granulomatosis and angiitis was first reported as a disease entity separate from polyarteritis nodosa in 1951 by Churg and Strauss. It is characterized by bronchial asthma, eosinophilia, and vasculitis and is especially rare in women of reproductive age, though, when present, may be associated with fetal mort...

journal_title：International archives of allergy and immunology

authors： Ogasawara M,Kajiura S,Inagaki H,Sasa H,Aoki K,Yagami Y

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Intravenous immunoglobulin (IVIG) is the mainstay therapy in human immune deficiency states characterized by qualitative and quantitative reductions in B cells. In addition, however, there is widespread use of IVIG in a number of other areas, including neuroimmunologic, infectious, dermatologic, hematologic,...

journal_title：International archives of allergy and immunology

authors： Kumar A,Teuber SS,Gershwin ME

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Several studies have examined the relationship of asthma with serum dyslipidemia and reported positive, negative or no association. Most studies were limited by their cross-sectional design and the wide age range of the participants. In a cohort of children in Cyprus, we explored the association of asthma wi...

journal_title：International archives of allergy and immunology

authors： Yiallouros PK,Savva SC,Kolokotroni O,Dima K,Zerva A,Kouis P,Bousquet J,Middleton N

更新日期：2014-01-01 00:00:00

abstract：:In contrast to mast cells and basophils, the high affinity IgE receptor (FcepsilonRI) on antigen-presenting cells (APC) shows structural and functional differences. It consists only of a minimal structure of one alpha- and two gamma-chains and enables APC to efficiently take up and present antigen in IgE-mediated dela...

journal_title：International archives of allergy and immunology

authors： Kraft S,Katoh N,Novak N,Koch S,Bieber T

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Human leukocyte antigen G (HLA-G) is a nonclassical major histocompatibility complex class I gene. HLA-G stimulates Th2 cytokine secretion by peripheral blood mononuclear cells. The role of soluble HLA-G (sHLA-G) in bronchial asthma is incompletely understood and the plasma level of sHLA-G in asthmatic child...

journal_title：International archives of allergy and immunology

authors： Tahan F,Patiroglu T

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Allergic reactions occur rarely in patients with chronic helminth infections, although FcepsilonRI-bearing cells are sensitized with anti-parasite IgE and are exposed to antigen. The inhibition of allergic reactivity is due to 'blocking antibodies', predominantly IgG4. IgG4 antibodies represent 50-95% of ant...

journal_title：International archives of allergy and immunology

authors： Agresti A,Vercelli D

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Epidemiological data on food allergy are scarce in African countries. We studied the prevalence of food sensitization in Ghanaian schoolchildren. METHODS:Children (5-16 years; n = 1,714) from 9 Ghanaian schools were given parental consent to participate in the study. Adverse reactions and food consumption w...

journal_title：International archives of allergy and immunology

authors： Obeng BB,Amoah AS,Larbi IA,Yazdanbakhsh M,van Ree R,Boakye DA,Hartgers FC

更新日期：2011-01-01 00:00:00

abstract：:Chlorhexidine is a commonly used antiseptic and disinfectant in the health-care setting. Its usage has increased in recent years with intensive campaigns and infection control guidelines to combat hospital-acquired infections. As a result, patients and health-care workers (HCW) are exposed to increasing chlorhexidine ...

journal_title：International archives of allergy and immunology

authors： Hong CC,Wang SM,Nather A,Tan JH,Tay SH,Poon KH

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Pollen are monitored in Europe by a network of about 400 pollen traps, all operated manually. To date, automated pollen monitoring has only been feasible in areas with limited variability in pollen species. There is a need for rapid reporting of airborne pollen as well as for alleviating the workload of manu...

journal_title：International archives of allergy and immunology

authors： Oteros J,Pusch G,Weichenmeier I,Heimann U,Möller R,Röseler S,Traidl-Hoffmann C,Schmidt-Weber C,Buters JT

更新日期：2015-01-01 00:00:00

abstract：:Eosinophils used to be thought of as regulators of allergic inflammation, but there is now evidence to the contrary; eosinophils have been found to be the major effector cells responsible for the late asthmatic response (LAR), airway hyperresponsiveness (AHR) and, at least in part, airway remodeling by releasing leuko...

journal_title：International archives of allergy and immunology

authors： Matsumoto K,Saito H

更新日期：2001-08-01 00:00:00

abstract：:Most subjects without IgE to Dermatophagoides pteronyssinus do not have IgG to Der p 1 or Der p 2 (as measured by RIA). However, by immunoblot or ELISA, IgG reactivity (mostly IgG1) to mite components is easily detectable. This discrepancy is caused largely by immune reactivity to mite components with a high molecular...

journal_title：International archives of allergy and immunology

authors： Aalberse RC,Vermeulen E

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Airway closure is frequently observed in human asthma. However, limited information exists on the factors that cause this condition. In this study, an allergic cynomolgus monkey model was used to characterize the condition of airway closure and assess the contribution of histamine H1 receptors to this respon...

journal_title：International archives of allergy and immunology

authors： Skeans S,Lamca JE,House A,Celly CS,Hey JA,Chapman RW

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:We reported on the constitutive interferon-gamma receptor (IFN-gammaR) expression on eosinophils. But signal transduction through IFN-gammaR on eosinophils remains to be elucidated. In this study, we examined the involvement of the Jak/Stat pathway in the signaling of eosinophils after IFN-gammaR conjugation...

journal_title：International archives of allergy and immunology

authors： Ochiai K,Ishihara C,Tomioka H

更新日期：1999-02-01 00:00:00

abstract：:Volumetric air sampling was performed at Corpus Christi, Tex., September 1987 to August 1989. Grass aeropollen during all of 1988 accounted for 15.3% of total pollen captured during two major peaks, one in May and another during September and October. The remaining grass pollen, about one-quarter of the total, was fou...

journal_title：International archives of allergy and immunology

authors： Lewis WH,Dixit AB,Wedner HJ

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Exposure and sensitization to pet allergens are associated with allergic asthma in children. Conflicting data have emerged regarding the potential benefit of air cleaners with respect to a reduction of indoor pet allergens and bronchial hyperresponsiveness (BHR). METHODS:In a randomized controlled trial 36 ...

journal_title：International archives of allergy and immunology

authors： Sulser C,Schulz G,Wagner P,Sommerfeld C,Keil T,Reich A,Wahn U,Lau S

更新日期：2009-01-01 00:00:00

abstract：:Superoxide (O2-) and nitric oxide (NO) production by polymorphonuclear leukocyte (PMNs) and monocytes in patients with liver cirrhosis were evaluated. PMNs obtained from cirrhotic patients were less effective than those from controls in producing O2- after stimulation with opsonized zymosan, while they were more effec...

journal_title：International archives of allergy and immunology

authors： Masini E,Mugnai L,Foschi M,Laffi G,Gentilini P,Mannaioni PF

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Ultra-rush regimens for administering sublingual immunotherapy to patients with allergies are becoming more widespread. We aimed to assess treatment safety for patients with allergic rhinitis with or without asthma caused by Dermatophagoides house dust mites. METHODS:This observational study at 5 Spanish ce...

journal_title：International archives of allergy and immunology

authors： Roger A,Justicia JL,Navarro LÁ,Eseverri JL,Ferrès J,Malet A,Alvà V

更新日期：2011-01-01 00:00:00

abstract：:Allergens from the pollen of Parthenium hysterophorus (American feverfew), responsible for high incidence of allergic rhinitis, were found by immunoprint analysis to be localized on the surface of the pollen grains. The allergens were released very rapidly when extracted in vitro. The allergenic activity of the rapid ...

journal_title：International archives of allergy and immunology

authors： Gupta N,Sriramarao P,Kori R,Rao PV

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The 2S albumins are a group of storage proteins that occur widely in seeds of dicotyledonous plants. The widespread distribution and stability to digestion of allergenic 2S albumins raise the question of why some members of this family present in important food sources, such as soybean, are not regarded as m...

journal_title：International archives of allergy and immunology

authors： Lin J,Shewry PR,Archer DB,Beyer K,Niggemann B,Haas H,Wilson P,Alcocer MJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The human IgE response is associated with allergy and with host defence against parasitic worms. A response to Sm22.6, the dominant IgE antigen in adult Schistosoma mansoni worms, correlates with resistance to re-infection after treatment. Sm22.6 is one of a family of EF-hand containing parasite proteins wit...

journal_title：International archives of allergy and immunology

authors： Fitzsimmons CM,McBeath R,Joseph S,Jones FM,Walter K,Hoffmann KF,Kariuki HC,Mwatha JK,Kimani G,Kabatereine NB,Vennervald BJ,Ouma JH,Dunne DW

更新日期：2007-01-01 00:00:00